Use of hydrophilic polymer coatings for control of electroosmosis and protein adsorption

The purpose of this project was to examine the utility of polyethylene glycol (PEG) and dextran coatings for control of electroosmosis and protein adsorption; electroosmosis is an important, deleterious process affecting electrophoretic separations, and protein adsorption is a factor which needs to be controlled during protein crystal growth to avoid multiple nucleation sites. Performance of the project required use of X-ray photoelectron spectroscopy to refine previously developed synthetic methods. The results of this spectroscopic examination are reported. Measurements of electroosmotic mobility of charged particles in appropriately coated capillaries reveals that a new, one-step route to coating capillaries gives a surface in which electroosmosis is dramatically reduced. Similarly, both PEG and dextran coatings were shown by protein adsorption measurements to be highly effective at reducing protein adsorption on solid surfaces. These results should have impact on future low-g electrophoretic and protein crystal growth experiments

Highly Non-Linear Optical (NLO) organic crystals

This research project involves the synthesis and characterization of organic materials having powerful nonlinear optical (NLO) properties and the growth of highly ordered crystals and monomolecular films of these materials. Research in four areas is discussed: theoretical design of new materials, characterization of NLO materials, synthesis of new materials and development of coupling procedures for forming layered films, and improvement of the techniques for vapor phase and solution phase growth of high quality organic crystals. Knowledge gained from these experiments will form the basis for experiments in the growth of these crystals

Physical properties of immiscible polymers

The demixing of immiscible polymers in low gravity is discussed. Applications of knowledge gained in this research will provide a better understanding of the role of phase segregation in determining the properties of polymer blends made from immiscible polymers. Knowledge will also be gained regarding the purification of biological materials by partitioning between the two liquid phases formed by solution of the polymers polyethylene glycol and dextran in water. Testing of new apparatus for space flight, extension of affinity phase partitioning, refinement of polymer chemistry, and demixing of isopycnic polymer phases in a one gravity environment are discussed

Rating Agencies in the Face of Regulation

This paper develops a theoretical framework to shed light on variation in credit rating standards over time and across asset classes. Ratings issued by credit rating agencies serve a dual role: they provide information to investors and are used to regulate institutional investors. We show that introducing rating-contingent regulation that favors highly rated securities may increase or decrease rating informativeness, but unambiguously increases the volume of highly rated securities. If the regulatory advantage of highly rated securities is sufficiently large, delegated information acquisition is unsustainable, since the rating agency prefers to facilitate regulatory arbitrage by inflating ratings. Our model relates rating informativeness to the quality distribution of issuers, the complexity of assets, and issuers\u27 outside options. We reconcile our results with the existing empirical literature and highlight new, testable implications, such as repercussions of the Dodd-Frank Act

Blame it on the Two Black Crows / music by Harry Harris; words by Haven Gillespie

Cover: drawing of two crows dressed in tuxedos; Publisher: Milton Weil Music Co. (Chicago)https://egrove.olemiss.edu/sharris_d/1079/thumbnail.jp

Casimir effect for the scalar field under Robin boundary conditions: A functional integral approach

In this work we show how to define the action of a scalar field in a such a way that Robin boundary condition is implemented dynamically, i.e., as a consequence of the stationary action principle. We discuss the quantization of that system via functional integration. Using this formalism, we derive an expression for the Casimir energy of a massless scalar field under Robin boundary conditions on a pair of parallel plates, characterized by constants $c_1$ and $c_2$. Some special cases are discussed; in particular, we show that for some values of $c_1$ and $c_2$ the Casimir energy as a function of the distance between the plates presents a minimum. We also discuss the renormalization at one-loop order of the two-point Green function in the $\lambda\phi^4$ theory submitted to Robin boundary condition on a plate.Comment: 16 pages, 2 figures. Version 2: contains a new section on the renormalization of the two-point Green function in the presence of a flat boundary. Accepted for publication in J. Phys.

Casimir Force on a Micrometer Sphere in a Dip: Proposal of an Experiment

The attractive Casimir force acting on a micrometer-sphere suspended in a spherical dip, close to the wall, is discussed. This setup is in principle directly accessible to experiment. The sphere and the substrate are assumed to be made of the same perfectly conducting material.Comment: 11 pages, 1 figure; to appear in J. Phys. A: Math. Ge