Assessment of Groundnut Elite Lines under Drought Conditions and Selection of Tolerance Associated Traits

Investigation of groundnut genotypes response to drought stress could contribute to improving drought tolerance and productivity. The objective of this study was to investigate new improved groundnut varieties response to drought stress under controlled conditions to identify tolerant materials and drought tolerance related traits.Thus, three experiments were conducted during offseasons: two experiments in lysimetric system in 2017 and 2018 and one experiment in pots in 2017, to assess twelve varieties in a randomized complete block design with 2 water regimes and 4 replications.The water regimes were a full irrigation (WW) and an intermittent drought imposed at flowering times (WS). The investigated morphophysiological traits like transpiration, specific leaf area, root dry matter, root length density, and yield components decreased underWS. Significant year effect and genotypic variation were observed on most of investigated traits. Genotypes ICGV 92206 and ICGV 06319 showed low transpiration and revealed high pod yielding and early maturing genotypes under both water regimes, while genotypes ICGV 92035, ICGV 92195, ICGV 02038, ICGV 07211, and ICGV 07210 were drought-sensitive for pods production but produced high haulm under both water regimes. ICGV 92206, ICGV 02005, ICGV 02125, and ICGV 06319 showed higher yielding than 55-437 and Fleur 11. In this study, low total transpiration to control water loss, chlorophyll content, and root length density revealed drought tolerance associated traits for pod production, while TTW, TE, RDW, and RV revealed drought tolerance associated traits for fodder production

Sphingolipid paracrine signaling impairs keratinocyte adhesion to promote melanoma invasion.

Melanoma is the deadliest form of skin cancer due to its propensity to metastasize. It arises from melanocytes, which are attached to keratinocytes within the basal epidermis. Here, we hypothesize that, in addition to melanocyte-intrinsic modifications, dysregulation of keratinocyte functions could initiate early-stage melanoma cell invasion. We identified the lysolipid sphingosine 1-phosphate (S1P) as a tumor paracrine signal from melanoma cells that modifies the keratinocyte transcriptome and reduces their adhesive properties, leading to tumor invasion. Mechanistically, tumor cell-derived S1P reduced E-cadherin expression in keratinocytes via S1P receptor dependent Snail and Slug activation. All of these effects were blocked by S1P2/3 antagonists. Importantly, we showed that epidermal E-cadherin expression was inversely correlated with the expression of the S1P-producing enzyme in neighboring tumors and the Breslow thickness in patients with early-stage melanoma. These findings support the notion that E-cadherin loss in the epidermis initiates the metastatic cascade in melanoma

The Fukushima Daiichi Accident

The Fukushima Daiichi Accident consists of a Report by the IAEA Director General and five technical volumes. It is the result of an extensive international collaborative effort involving five working groups with about 180 experts from 42 Member States with and without nuclear power programmes and several international bodies. It provides a description of the accident and its causes, evolution and consequences, based on the evaluation of data and information from a large number of sources available at the time of writing. The set contains six printed parts and five supplementary CD-ROMs. Contents: Report by the Director General; Technical Volume 1/5, Description and Context of the Accident; Technical Volume 2/5, Safety Assessment; Technical Volume 3/5, Emergency Preparedness and Response; Technical Volume 4/5, Radiological Consequences; Technical Volume 5/5, Post-accident Recovery; Annexes. The JRC contributed to volumes 1,2 and 3, which are attached.JRC.F.5-Nuclear Reactor Safety Assessmen

Protecting environmental flows through enhanced water licensing and water markets

To enable economically efficient future adaptation to water scarcity some countries are revising water management institutions such as water rights or licensing systems to more effectively protect ecosystems and their services. However, allocating more flow to the environment can mean less abstraction for economic production, or the inability to accommodate new entrants (diverters). Modern licensing arrangements should simultaneously enhance environmental flows and protect water abstractors who depend on water. Making new licensing regimes compatible with tradable water rights is an important component of water allocation reform. Regulated water markets can help decrease the societal cost of water scarcity whilst enforcing environmental and/or social protections. In this article we simulate water markets under a regime of fixed volumetric water abstraction licenses with fixed minimum flows or under a scalable water license regime (using water "shares") with dynamic environmental minimum flows. Shares allow adapting allocations to available water and dynamic environmental minimum flows vary as a function of ecological requirements. We investigate how a short-term spot market manifests within each licensing regime. We use a river-basin-scale hydroeconomic agent model that represents individual abstractors and can simulate a spot market under both licensing regimes. We apply this model to the Great Ouse River basin in eastern England with public water supply, agricultural, energy and industrial water-using agents. Results show the proposed shares with dynamic environmental flow licensing system protects river flows more effectively than the current static minimum flow requirements during a dry historical year, but that the total opportunity cost to water abstractors of the environmental gains is a 10–15% loss in economic benefits

Protecting environmental flows through enhanced water licensing and water markets

To enable economically efficient future adaptation to water scarcity some countries are revising water management institutions such as water rights or licensing systems to more effectively protect ecosystems and their services. Allocating more flow to the environment though can mean less abstraction for economic production, or the inability to accommodate new entrants (diverters). Modern licensing arrangements should simultaneously enhance environmental flows and protect water abstractors who depend on water. Making new licensing regimes compatible with tradable water rights is an important component of water allocation reform. Regulated water markets can help decrease the societal cost of water scarcity whilst enforcing environmental and/or social protections. In this article we simulate water markets under a regime of fixed volumetric water abstraction licenses with fixed minimum flows or under a scalable water license regime (using water "shares") with dynamic environmental minimum flows. Shares allow adapting allocations to available water and dynamic environmental minimum flows can vary as a function of ecological requirements. We investigate how a short-term spot market manifests within each licensing regime. We use a river-basin-scale hydro-economic agent model that represents individual abstractors and can simulate a spot market under both licensing regimes. We apply this model to the Great Ouse river basin in Eastern England with public water supply, agricultural, energy and industrial water using agents. Results show the proposed shares with dynamic environmental flow licensing system protects river flows more effectively than the current static minimum flow requirements during a dry historical year, but that the total opportunity cost to water abstractors of the environmental gains is a 10 to 15% loss in economic benefits

Many-Objective Optimization of Sustainable Drainage Systems in Urban Areas with Different Surface Slopes

Sustainable urban drainage systems are multi-functional nature-based solutions that can facilitate flood management in urban catchments while improving stormwater runoff quality. Traditionally, the evaluation of the performance of sustainable drainage infrastructure has been limited to a narrow set of design objectives to simplify their implementation and decision-making process. In this study, the spatial design of sustainable urban drainage systems is optimized considering five objective functions, including minimization of flood volume, flood duration, average peak runoff, total suspended solids, and capital cost. This allows selecting an ensemble of admissible portfolios that best trade-off capital costs and the other important urban drainage services. The impact of the average surface slope of the urban catchment on the optimal design solutions is discussed in terms of spatial distribution of sustainable drainage types. Results show that different subcatchment slopes result in non-uniform distributional designs of sustainable urban drainage systems, with higher capital costs and larger surface areas of green assets associated with steeper slopes. This has two implications. First, urban areas with different surface slopes should not have a one-size-fits-all design policy. Second, spatial equality must be taken into account when applying optimization models to urban subcatchments with different surface slopes to avoid unequal distribution of environmental and human health co-benefits associated with green drainage infrastructure