Application of weight-height ratios and body indices to juvenile populations--the national health examination survey data

Properties of four weight-height ratios were studed in data from the U.S. Health Examination Survey (Cycles II and III) of a national probability sample of youths aged 6-17 yr (N = 13,867). These ratios (weight/height, weight/height2, weight/height3, weight/body surface area) were examined for their correlation with adiposity (infrascapular skinfold thickness) and muscle mass (estimated muscle circumference) and for their relationship to selected physiologic and biochemical measurements. Weight/height2 (Quetelet's index) correlates best with skinfold thickness for all age-race-sex groups. However, weight-height ratios may be a better indicator of muscle mass than of adiposity because the ratios generally show higher correlations with muscle circumference than with skinfold thickness. Weight/body surface area (BSA index) is the ratio which shows the highest overall correlation with muscle circumference. The relationships of the ratios are different for various biochemical and physiologic parameters, and these data can be used for selection of an index appropriate to the investigative aims of the study.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/22752/1/0000307.pd

The ionization produced in nuclear emulsion by very relativistic particles

In order to determine the shape of the ionization curve in nuclear emulsions at values of ϒ˃100, we have measured the blob density of relativistic electron tracks. The pv of the pair produced electrons used was determined by multiple scattering. A total of 84.45 centimeters of electron track was blob taunted and scattered. From ϒ = 100 to ϒ = 5400 the data were combined into 14 points each with a statistical uncertainty on blob density of less than 1%. These points indicate a level "plateau" and show no deviation from this plateau within our statistical accuracy. Pions were used to estimate the minimum of the ionization curve 5 and ratio of blob density plateau to blob density minimum is estimated to be 1.140 ± .020.http://www.archive.org/details/ionizationproduc00hansLieutenant, United States Coast GuardLieutenant, United States NavyLieutenant, United States Nav

Highly Plasma Etch-Resistant Photoresist Composition Containing a Photosensitive Polymeric Titania Precursor

A composition is derived from an addition polymerizable organotitanium polymer which upon exposure to an oxygen plasma or baking in air, is converted to titanium dioxide (titania) or is converted to a mixed, titanium-containing metal oxide. The metal oxide formed in situ imparts etch- resistant action to a patterned photoresist layer. The composition may also be directly deposited and patterned into permanent metal oxide device features by a photolithographic process

Structural and Magnetic Properties of La Mn₁₋ₓFeₓO₃ (0 \u3c x \u3c 1.0)

Electronic, structural, and magnetic properties of Mn-doped lanthanum ferrites were studied by neutron diffraction, superconducting quantum interference device, and impedance spectroscopy. Neutron diffraction refinements were performed with the constraint of full La occupancy, which showed the presence of excess oxygen when x \u3c 0.4. Mixed valent Mn cations and cation vacancies, therefore, exist in all the samples. The samples with x \u3e 0.7 are magnetically ordered at room temperature with orthorhombic symmetry (Pbnm). When x \u3c 0.3 the structure is rhombohedral and magnetically disordered above 16 K. The majority carriers, electron holes, correspond to high oxidation states of Mn. The carrier concentration is determined from the Seebeck coefficients, and is a function of temperature and Fe concentration. The measurements of conductivity and Seebeck coefficients show polaron hopping at elevated temperatures

67/12/12 Oral Arguments before the US Supreme Court

Tuesday, December 12, 1967 oral arguments before the United States Supreme Court

Variation and disparities in awareness of myocardial infarction symptoms among adults in the United States

Importance: Prompt recognition of myocardial infarction symptoms is critical for timely access to lifesaving emergency cardiac care. However, patients with myocardial infarction continue to have a delayed presentation to the hospital.Objective: To understand the variation and disparities in awareness of myocardial infarction symptoms among adults in the United States.Design, setting, and participants: This cross-sectional study used data from the 2017 National Health Interview Survey among adult residents of the United States, assessing awareness of the 5 following common myocardial infarction symptoms among different sociodemographic subgroups: (1) chest pain or discomfort, (2) shortness of breath, (3) pain or discomfort in arms or shoulders, (4) feeling weak, lightheaded, or faint, and (5) jaw, neck, or back pain. The response to a perceived myocardial infarction (ie, calling emergency medical services vs other) was also assessed.Main outcomes and measures: Prevalence and characteristics of individuals who were unaware of myocardial infarction symptoms and/or chose not to call emergency medical services in response to these symptoms.Results: Among 25 271 individuals (13 820 women [51.6%; 95% CI, 50.8%-52.4%]; 17 910 non-Hispanic white individuals [69.9%; 95% CI, 68.2%-71.6%]; and 21 826 individuals [82.7%; 95% CI, 81.5%-83.8%] born in the United States), 23 383 (91.8%; 95% CI, 91.0%-92.6%) considered chest pain or discomfort a symptom of myocardial infarction; 22 158 (87.0%; 95% CI, 86.1%-87.8%) considered shortness of breath a symptom; 22 064 (85.7%; 95% CI, 84.8%-86.5%) considered pain or discomfort in arm a symptom; 19 760 (77.0%; 95% CI, 76.1%-77.9%) considered feeling weak, lightheaded, or faint a symptom; and 16 567 (62.6%; 95% CI, 61.6%-63.7%) considered jaw, neck, or back pain a symptom. Overall, 14 075 adults (53.0%; 95% CI, 51.9%-54.1%) were aware of all 5 symptoms, whereas 4698 (20.3%; 95% CI, 19.4%-21.3%) were not aware of the 3 most common symptoms and 1295 (5.8%; 95% CI, 5.2%-6.4%) were not aware of any symptoms. Not being aware of any symptoms was associated with male sex (odds ratio [OR], 1.23; 95% CI, 1.05-1.44; P = .01), Hispanic ethnicity (OR, 1.89; 95% CI, 1.47-2.43; P \u3c .001), not having been born in the United States (OR, 1.85; 95% CI, 1.47-2.33; P \u3c .001), and having a lower education level (OR, 1.31; 95% CI, 1.09-1.58; P = .004). Among 294 non-Hispanic black or Hispanic individuals who were not born in the United States, belonged to the low-income or lowest-income subgroup, were uninsured, and had a lower education level, 61 (17.9%; 95% CI, 13.3%-23.6%) were not aware of any symptoms. This group had 6-fold higher odds of not being aware of any symptoms (OR, 6.34; 95% CI, 3.92-10.26; P \u3c .001) compared with individuals without these characteristics. Overall, 1130 individuals (4.5%; 95% CI, 4.0%-5.0%) chose a different response than calling emergency medical services in response to a myocardial infarction.Conclusions and relevance: Many adults in the United States remain unaware of the symptoms of and appropriate response to a myocardial infarction. In this study, several sociodemographic subgroups were associated with a higher risk of not being aware. They may benefit the most from targeted public health initiatives

Rheumatoid Factor as a Potentiator of Anti–Citrullinated Protein Antibody–Mediated Inflammation in Rheumatoid Arthritis

Objective. The co-occurrence of rheumatoid factor (RF) and anti–citrullinated protein antibody (ACPA) positivity in rheumatoid arthritis (RA) is well described. However, the mechanisms underlying the potential interaction between these 2 distinct autoantibodies have not been well defined. The aim of this study was to evaluate the epidemiologic and molecular interaction of ACPAs and RF and its association with both disease activity and measures of RA-associated inflammation. Methods. In a cohort of 1,488 US veterans with RA, measures of disease activity and serum levels of cytokines and multiplex ACPAs were compared between the following groups of patients: double-negative (anti–cyclic citrullinated peptide [anti-CCP]-/RF-), anti-CCP+/RF-, anti-CCP-/RF+, or double-positive (anti-CCP+/RF+). Additional studies were performed using an in vitro immune complex (IC) stimulation assay in which macrophages were incubated with ACPA ICs in the presence or absence of monoclonal IgM-RF, and tumor necrosis factor α production measured as a readout of macrophage activation. Results. Compared with the double-negative subgroup (as well as each single-positive subgroup), the double-positive subgroup exhibited higher disease activity as well as higher levels of C-reactive protein and inflammatory cytokines (all P \u3c 0.001). In vitro stimulation of macrophages by ACPA ICs increased cytokine production, and the addition of monoclonal IgM-RF significantly increased macrophage tumor necrosis factor α production (P = 0.003 versus ACPA ICs alone). Conclusion. The combined presence of ACPAs and IgM-RF mediates increased proinflammatory cytokine production in vitro and is associated with increased systemic inflammation and disease activity in RA. Our data suggest that IgM-RF enhances the capacity of ACPA ICs to stimulate macrophage cytokine production, thereby providing a mechanistic link by which RF enhances the pathogenicity of ACPA ICs in RA