Co‐operative cross‐platform courseware development

The UKMCC (UK Mathematics Courseware Consortium) is a Consortium funded under TLTP (Training and Learning Technology Programme) to produce courseware for service mathematics teaching, using the SEFI (Société Européenne pour la Formation des Ingénieurs) syllabus. There are agreed courseware design guidelines and a simple courseware management system which allows cross‐referencing. Courseware is divided into modules, with an author as implementer for each. On any one hardware platform, a variety of authoring languages is possible. Across hardware platforms, the design guidelines ensure that conversion is possible, and will preserve look and feel. We argue here that these arrangements provide a basis for continued co‐operation between authors and future development as the technology changes

Sites of Biosynthesis of Outer and Inner Membrane Proteins of Neurospora crassa Mitochondria

Outer and inner membranes of Neurospora crassa mitochondria were separated by the combined swelling, shrinking, sonication procedure. Membranes were characterized by electron microscopy and by marker enzyme activities. A red carotenoid pigment was found to be concentrated in the outer membrane. The inner mitochondrial membrane was resolved into about 20 protein bands on polyacrylamide gel electrophoresis, whereas the outer membrane shows essentially one single protein band. Only negligible incorporation of radioactive amino acids occurs into outer membrane when isolated mitochondria are synthesizing polypeptide chains. In agreement with this observation labeling of outer membrane protein is almost entirely blocked, when whole Neurospora cells are incubated with radioactive amino acids in the presence of cycloheximide, an inhibitor of cytoplasmic protein synthesis. Finally, the essential electrophoretic protein band from outer membrane does not become labeled when mitochondria are incubated with radioactive amino acids either in vitro or in vivo in the presence of cycloheximide. It is concluded that the vast majority, if not all, of the outer membrane protein is synthesized by the cytoplasmic system and that polypeptide chains formed by the mitochondrial ribosomes are integrated into the inner mitochondrial membrane

Comment on ``Cosmological Gamma Ray Bursts and the Highest Energy Cosmic Rays''

In a letter with the above title, published some time ago in PRL, Waxman made the interesting suggestion that cosmological gamma ray bursts (GRBs) are the source of the ultra high energy cosmic rays (UHECR). This has also been proposed independently by Milgrom and Usov and by Vietri. However, recent observations of GRBs and their afterglows and in particular recent data from the Akeno Great Air Shwoer Array (AGASA) on UHECR rule out extragalactic GRBs as the source of UHECR.Comment: Comment on a letter with the above title published by E. Waxman in PRL 75, 386 (1995). Submitted for publication in PRL/Comment

Full polar cap cascade scenario: γ\gamma-ray and X-ray luminosities from spin-powered pulsars

We modify polar cap cascade picture to include the ICS of the higher generation pairs. In such a ``full-cascade'' scenario, not only the perpendicular portion of the energy of the pairs goes to high energy radiation via SR, but the parallel portion of the energy of the pairs can also contribute to high energy emission via ICS with the soft thermal photons from either the full neutron star surface or the hot polar cap. An important output of such a scenario is that the soft tail of the ICS spectrum can naturally result in a non-thermal X-ray component which can contribute to the luminosities observed by ROSAT and ASCA. Here we present an analytic description of such a full polar cap cascade scenario within the framework of Harding & Muslimov acceleration model. We present the theoretical predictions of the $\gamma$-ray luminosities, the thermal and non-thermal X-ray luminosities for the known spin-powered X-ray pulsars. Our results show that the observed different dependences of the high energy luminosities on the pulsar spin-down luminosities, i.e., $L_\gamma \propto (L_{\rm sd})^{1/2}$ and $L_x \sim 10^{-3} L_{\rm sd}$, are well reproduced. Our model predicts that the {\em pulsed} soft X-rays in the ROSAT band from most of the millisecond pulsars might be of thermal origin if there is no strong multipole field components near the surfaces of these pulsars.Comment: 23 pages, emulateapj style, final version to appear in the Astrophysical Journa

On the Origin of X-ray Emission From Millisecond Pulsars in 47 Tuc

The observed spectra and X-ray luminosities of millisecond pulsars in 47 Tuc can be interpreted in the context of theoretical models based on strong, small scale multipole fields on the neutron star surface. For multipole fields that are relatively strong as compared to the large scale dipole field, the emitted X-rays are thermal and likely result from polar cap heating associated with the return current from the polar gap. On the other hand, for weak multipole fields, the emission is nonthermal and results from synchrotron radiation of $e^{\pm}$ pairs created by curvature radiation. The X-ray luminosity, $L_x$, is related to the spin down power, $L_{sd}$, expressed in the form $L_x \propto L^{\beta}_{sd}$ with $\beta \sim 0.5$ and $\sim 1$ for strong and weak multipole fields respectively. If the polar cap size is of the order of the length scale of the multipole field, $s$ and $\beta \sim 0.5$, the polar cap temperature is $\sim 3 \times 10^6 K (\frac{L_{sd}}{10^{34}erg s^{-1}})^{1/8} (\frac{s}{3\times 10^4 cm})^{-1/2}$. A comparison of the X-ray properties of millisecond pulsars in globular clusters and in the Galactic field suggests that the emergence of relatively strong small scale multipole fields from the neutron star interior may be correlated with the age and evolutionary history of the underlying neutron star.Comment: 25 pages, 2 figures, accepted for publication in Ap

A Neurospora crassa mutant which overaccumulates carotenoid pigments

A Neurospora crassa mutant which overaccumulates carotenoid pigment

Source population synthesis and the Galactic diffuse gamma-ray emission

Population synthesis is used to study the contribution from undetected sources to the Galactic ridge emission measured by EGRET. Synthesized source counts are compared with the 3rd EGRET catalogue at low and high latitudes. For pulsar-like populations, 5-10% of the emission >100 MeV comes from sources below the EGRET threshold. A steeper luminosity function can increase this to 20% without violating EGRET source statistics. Less luminous populations can produce much higher values without being detected. Since the unresolved source spectrum is different from the interstellar spectrum, it could provide an explanation of the observed MeV and GeV excesses above the predictions, and we give an explicit example of how this could work.Comment: Astrophysics and Space Science, in press. (Proceedings of Conference 'The multi-messenger approach to high-energy gamma-ray sources', Barcelona, 2006). Minor changes for accepted version, updated reference