Level of awareness, attitude and perception about human papilloma virus vaccine among University of Mauritius students

The rising number of HPV infections is of global concern. Hence, this study helps to assess awareness, attitude, and perception regarding the HPV vaccine among young people of various fields and both genders as they are equally susceptible to the infection. These are essential to prevent complications like cervical cancer. A cross- sectional quantitative study was carried out, involving online questionnaires in English, French and Kreol Morisien languages distributed on various student platforms. There was randomization of data. Participation was entirely voluntary. 58% of respondents have heard of HPV infection. Female gender and Health Sciences students were more aware of HPV infection. 68.5% of respondents reported that they think the vaccine is safe and 77 % of participants are willing to be vaccinated against HPV post the survey. Awareness about HPV infection and vaccines is relatively high among girls and Health Sciences students. Public health efforts to educate students on HPV and cervical cancer should be strengthened to help curb the rising incidence in Mauritius. Therefore, stakeholders should be proactive to address vaccine hesitancy and increase awareness of vaccine safety. Boys should also be included in the National Immunization Programme to enhance the primary prevention of HPV infection. (Afr J Reprod Health 2022; 26[12]: 41-48). Le nombre croissant d'infections au VPH est une préoccupation mondiale. Par conséquent, cette étude aide à évaluer la sensibilisation, l'attitude et la perception concernant le vaccin contre le VPH chez les jeunes de divers domaines et des deux sexes, car ils sont également sensibles à l'infection. Ceux-ci sont essentiels pour prévenir les complications comme le cancer du col de l'utérus. Une étude quantitative transversale a été réalisée, impliquant des questionnaires en ligne en langues anglaise, française et créole morisienne distribués sur différentes plateformes étudiantes. Il y a eu une randomisation des données. La participation était entièrement volontaire. 58% des répondants ont entendu parler de l'infection au VPH. Les étudiantes et étudiants en sciences de la santé étaient plus conscients de l'infection au VPH. 68,5 % des répondants ont déclaré qu'ils pensaient que le vaccin était sûr et 77 % des participants étaient disposés à se faire vacciner contre le VPH après l'enquête. La sensibilisation à l'infection au VPH et aux vaccins est relativement élevée chez les filles et les étudiants en sciences de la santé. Les efforts de santé publique pour éduquer les étudiants sur le VPH et le cancer du col de l'utérus devraient être renforcés pour aider à freiner l'augmentation de l'incidence à Maurice. Par conséquent, les parties prenantes doivent être proactives pour lutter contre la réticence à la vaccination et accroître la sensibilisation à la sécurité des vaccins. Les garçons devraient également être inclus dans le programme national de vaccination afin d'améliorer la prévention primaire de l'infection par le VPH. (Afr J Reprod Health 2022; 26[12]: 41-48)

20 Years Of Progress In Dengue Hemorrhagic Fever And Other Arboviral Diseases Research

Throughout the 20 year history of U.S. Naval Medical Research Unit No. 2 Detachment (NAMRU), many viruses and viral diseases have been studied. The greatest emphasis has been in the field of arboviruses, specifically dengue virus, chikungunya virus, and Japanese B encephalitis virus. The initial focus of the work was to define the extent of the threat posed by these viruses. Studies were conducted to determine antibody prevalence, and to determine the etiologies of infectious febrile disease in hospitalized patients. Later the work advanced into more specific areas, especially the entomologic and clinical components of these viruses. Little was known of the incidence or kind of arbovirus infections in Indonesia when NAMRU was established. Previous serological studies had used the cross reactive haemagglutination assay. Green et al. in 1973 provided convincing serological evidence of infections with chikungunya virus and group B arboviruses by using the specific virus neutralization assay. These results demonstrated the need for further studies to isolate the causative agent, to describe the epidemiology, and to investigate the clinical features of the associated disease

'Always between two cultures': young British Bangladeshis and their mothers' views on sex and relationships.

This paper presents data on the sexual health perspectives of young British Bangladeshis and their mothers. It discusses the implications of these data for the development of appropriate sexual health education. Between April and September 2006, 36 young people and 25 mothers of Bangladeshi young people were interviewed through seven focus group discussions. Groups were gender and age specific (16-18 years, 19-20 years and mothers). Recruitment took place in community-based organisations in an inner city London borough. Mothers expressed concern about pre-marital sex but felt unable to control out-of-home activity. Feelings of isolation, lack of control and communication difficulties were key issues for them. Young people had varied perspectives on pre-marital sex. Some experienced emotional conflict between what was expected of them in terms of their faith and their engagement in intimate relationships. Both the young people and mothers highlighted the need for sex and relationship education to take account of cultural perspectives and the involvement of parents and the wider community. However, parents and community representatives require information and communication support to enable this involvement. Sex and relationships education content needs to be inclusive, have both secular and faith perspectives and engage where relevant with local communities

Synthesis of 3,5-Bis(trifluoromethyl)phenyl-Substituted Pyrazole Derivatives as Potent Growth Inhibitors of Drug-Resistant Bacteria

Enterococci and methicillin-resistant S. aureus (MRSA) are among the menacing bacterial pathogens. Novel antibiotics are urgently needed to tackle these antibiotic-resistant bacterial infections. This article reports the design, synthesis, and antimicrobial studies of 30 novel pyrazole derivatives. Most of the synthesized compounds are potent growth inhibitors of planktonic Gram-positive bacteria with minimum inhibitory concertation (MIC) values as low as 0.25 µg/mL. Further studies led to the discovery of several lead compounds, which are bactericidal and potent against MRSA persisters. Compounds 11, 28, and 29 are potent against S. aureus biofilms with minimum biofilm eradication concentration (MBEC) values as low as 1 µg/mL

The natural history of portal hypertensive gastropathy: influence of variceal eradication

Objective: The natural history and likelihood of bleeding from portal hypertensive gastropathy (PHG) present in patients with portal hypertension before endoscopic variceal obliteration may differ from that in patients who develop PHG during or after variceal eradication. Methods: A total of 967 variceal bleeders who had achieved variceal eradication by endoscopic sclerotherapy in the recent past were prospectively studied. In all, 88 (9.1%) patients (cirrhosis in 54, noncirrhotic portal fibrosis in 18, and extrahepatic portal vein obstruction in 16) had distinct mucosal lesions. PHG alone was present in 78, PHG with gastric antral vascular ectasia (GAVE) in eight, and GAVE alone in two patients. PHG was graded as mild or severe and according to whether present before (group A) or after endoscopic intervention (group B). Patients underwent regular endoscopy at follow-up to see if the PHG was transitory (disappearing within 3 months), persistent (no change), or progressive. Bleeding from PHG lesions was defined as acute or chronic. Results: Twenty-two (26%) patients had PHG before (group A) and 64 (74%) developed PHG after variceal eradication (group B). During a mean follow-up of 25.1 ± 14.2 months, PHG lesions disappeared in group A in only two patients (9%), but in group B in 28 (44%) patients (p < 0.05). PHG lesions more often progressed in the former as compared to the latter (18% vs 9.4%), p = NS). The incidence of bleeding was higher in group A than group B (32% vs 4.7%, p < 0.02). Bleeding from PHG occurred in 10 patients (11.6%); seven of them were from group A, and all had either progressive (n = 3) or persistent (n = 4) lesions. Conclusions: PHG developing after variceal eradication is often transitory and less severe. If PHG is pre-existing, endoscopic therapy for varices could worsen the PHG, with a likelihood of bleeding. Such patients may be benefited by concomitant beta-blocker therapy