Contribution of rock glacier discharge to late summer and fall streamflow in the Uinta Mountains, Utah, USA

Water draining from rock glaciers in the Uinta Mountains of Utah (USA) was analyzed and compared with samples of groundwater and water from the primary stream in a representative 5000 ha drainage. Rock glacier water resembles snowmelt in the early summer but evolves to higher values of d-excess and greatly elevated Ca and Mg content as the melt season progresses. This pattern is consistent with models describing a transition from snowmelt to melting of seasonal ice to melting of perennial ice in the rock glacier interior in late summer and fall. Water derived from this internal ice appears to have been the source of ∼25 % of the streamflow in this study area during September of 2021. This result emphasizes the significant role that rock glaciers can play in the hydrology of high-elevation watersheds, particularly in summers following a winter with below-average snowpack.</p

Examining the variability of rock glacier meltwater in space and time in high-elevation environments of Utah, United States

Rock glaciers are common geomorphic features in alpine landscapes and comprise a potentially significant but poorly quantified water resource. This project focused on three complementary questions germane to rock glacier hydrology: 1) Does the composition of rock glacier meltwater vary from year to year? 2) How dependent is the composition of rock glacier meltwater on lithology? And 3) How does the presence of rock glaciers in a catchment change stream water chemistry? To address these questions, we deployed automated samplers to collect water from late June through mid-October 2022 in two rock-glacierized mountain ranges in Utah, United States characterized by different lithologies. In the Uinta Mountains of northern Utah, where bedrock is predominantly quartzite, water was collected at springs discharging from two rock glaciers previously shown to release water in late summer sourced from internal ice. In the La Sal Mountains of southeastern Utah, where trachyte bedrock is widespread, water was collected at a rock glacier spring, along the main stream in a watershed containing multiple rock glaciers, and from a stream in a watershed where rock glaciers are absent. Precipitation was also collected, and data loggers for water temperature and electric conductivity were deployed. Water samples were analyzed for stable isotopes with cavity ring-down spectroscopy and hydrochemistry with ICP-MS. Our data show that water discharging from rock glaciers in the Uinta Mountains exhibits a shift from a snowmelt source to an internal ice source over the course of the melt season that is consistent from year to year. We also found that the chemistry of rock glacier water in the two study areas is notably different in ways that can be linked back to their contrasting bedrock types. Finally, in the La Sal Mountains, the properties of water along the main stream in a rock-glacierized basin resemble the properties of water discharging from rock glaciers, and strongly contrast with the water in a catchment lacking rock glaciers. Collectively these results underscore the role of rock glaciers as an agent influencing the hydrochemistry of water in high-elevation stream systems

Borehole breakout analysis: results from the AND-2A Well

To define the present-day stress field in the upper crust and to understand the recent tectonic activity in Antarctica, a study of breakout measurements along AND-2A well was performed. The borehole breakout is an important indicator of horizontal stress orientation and occurs when the stresses around the borehole exceed that required to cause compressive failure of the borehole wall (Bell and Gough, 1979; Zoback et al., 1985, Bell, 1990). The enlargement of the wellbore is caused by the development of intersecting conjugate shear planes that cause pieces of the borehole wall to spall off. Around a vertical borehole, stress concentration is greatest in the direction of the minimum horizontal stress (Shmin), hence, the long axes of borehole breakouts are oriented approximately perpendicular to the maximum horizontal stress orientation (SHmax). The orientation of breakouts along the AND-2A well was measured using acoustic (BHTV) and mechanical (Four-Arm Caliper) tools. Borehole televiewer (BHTV) provides an acoustic "image" of the borehole wall (360 degree coverage) and gives detailed information for investigation of fractures and stress analysis. The four-arm caliper is the oldest technique for borehole breakout identification and it is included in routine dipmeter logs. A quality value has been assigned to the well results in agreement with the World Stress Map quality ranking scheme (Zoback, 1992; Heidback et al., 2010) based mainly on the number, accuracy, and length of breakout measurements. The result is presented as rose diagram of the breakout directions where the length of each peak is proportional to the frequency and the width to the variance of its gaussian curve. We have analyzed the following curves to recognize the breakout: the azimuth of Pad 1 (P1az), the drift azimuth (HAZI), the two calipers with respect to the bit size (BZ) curve and the curve relative to the deviation of the well. The AND-2A Four-Arm Caliper data cover a depth interval between 637 down to 997 mbsl, that corresponds to 360 m of logged interval. We have distinguished breakouts and some washouts only in the interval from 753 to 825 mbsl. From borehole televiewer images, we have data from 398 mbsl down to 1136 mbsl. The BHTV worked well showing a lot of interesting features such as many bedding, lamination and fractures (natural and induced) but poor breakouts. The rare breakouts have also a small size (called protobreakouts) but they are consistent with induced features. Considering the breakout result from caliper and BHTV, the AND-2A borehole is unfortunately classified as D quality. This means that to obtain a reliable active stress field of the area it is necessary to compare this result with other available data

Mechanics and dynamics of X-chromosome pairing at X inactivation

At the onset of X-chromosome inactivation, the vital process whereby female mammalian cells equalize X products with respect to males, the X chromosomes are colocalized along their Xic (X-inactivation center) regions. The mechanism inducing recognition and pairing of the X’s remains, though, elusive. Starting from recent discoveries on the molecular factors and on the DNA sequences (the so-called "pairing sites") involved, we dissect the mechanical basis of Xic colocalization by using a statistical physics model. We show that soluble DNA-specific binding molecules, such as those experimentally identified, can be indeed sufficient to induce the spontaneous colocalization of the homologous chromosomes but only when their concentration, or chemical affinity, rises above a threshold value as a consequence of a thermodynamic phase transition. We derive the likelihood of pairing and its probability distribution. Chromosome dynamics has two stages: an initial independent Brownian diffusion followed, after a characteristic time scale, by recognition and pairing. Finally, we investigate the effects of DNA deletion/insertions in the region of pairing sites and compare model predictions to available experimental data

Synthetic amphipathic peptides resembling apolipoproteins stimulate the release of human placental lactogen

Previous studies from our laboratory demonstrated native high density lipoproteins and apolipoproteins AI, AII, and CI, stimulate the release of human placental lactogen (hPL) from trophoblast cells in culture. To examine the mechanisms by which these apolipoproteins stimulate hPL release, we have studied hPL secretion in response to several synthetic peptide analogs of the amphipathic helical structure of the apolipoproteins. The magnitude of the stimulation of hPL release in response to the analog peptides correlated with the ability to displace apolipoproteins from high density lipoprotein and with other measures of phospholipid binding affinity such as the increase in alpha-helicity and the size of complexes formed between the peptide and phospholipid. The correlation of stimulatory ability and lipid affinity suggests that the action of the apolipoproteins on hPL release may be mediated through an interaction with plasma membrane phospholipids

Downhole Measurements in the AND-2A Borehole, ANDRILL Southern McMurdo Sound Project, Antarctica

Under the framework of the ANDRILL Southern McMurdo Sound (SMS) Project successful downhole experiments were conducted in the 1138.54 metre (m)-deep AND-2A borehole. Wireline logs successfully recorded were: magnetic susceptibility, spectral gamma ray, sonic velocity, borehole televiewer, neutron porosity, density, calliper, geochemistry, temperature and dipmeter. A resistivity tool and its backup both failed to operate, thus resistivity data were not collected. Due to hole conditions, logs were collected in several passes from the total depth at ~1138 metres below sea floor (mbsf) to ~230 mbsf, except for some intervals that were either inaccessible due to bridging or were shielded by the drill string. Furthermore, a Vertical Seismic Profile (VSP) was created from ~1000 mbsf up to the sea floor. The first hydraulic fracturing stress measurements in Antarctica were conducted in the interval 1000-1138 mbsf. This extensive data set will allow the SMS Science Team to reach some of the ambitious objectives of the SMS Project. Valuable contributions can be expected for the following topics: cyclicity and climate change, heat flux and fluid flow, seismic stratigraphy in the Victoria Land Basin, and structure and state of the modern crustal stress field.Published57-683.2. Tettonica attivaN/A or not JCRrestricte

An influenza virus-inspired polymer system for the timed release of siRNA

Small interfering RNA silences specific genes by interfering with mRNA translation, and acts to modulate or inhibit specific biological pathways; a therapy that holds great promise in the cure of many diseases. However, the naked small interfering RNA is susceptible to degradation by plasma and tissue nucleases and due to its negative charge unable to cross the cell membrane. Here we report a new polymer carrier designed to mimic the influenza virus escape mechanism from the endosome, followed by a timed release of the small interfering RNA in the cytosol through a self-catalyzed polymer degradation process. Our polymer changes to a negatively charged and non-toxic polymer after the release of small interfering RNA, presenting potential for multiple repeat doses and long-term treatment of diseases