Which treatments help women with reduced libido?

Several treatments produce modest, but statistically significant, clinical increases in sexual desire and function in women. The testosterone transdermal patch improves hypoactive sexual desire disorder (HSDD) in postmenopausal women (strength of recommendation [SOR]: A, 2 randomized controlled trials [RCTs]). Bupropion may be effective for HSDD in premenopausal women (SOR: B, 2 RCTs). Sildenafil improves HSDD associated with selective serotonin reuptake inhibitors (SSRIs) (SOR: B, 1 RCT)

Does niacin decrease cardiovascular morbidity and mortality in CVD patients?

Q: Does niacin decrease cardiovascular morbidity and mortality in CVD patients? A: No. Niacin doesn't reduce cardio- vascular disease (CVD) morbidity or mortality in patients with established disease (strength of recommendation [SOR]: A, meta-analyses of randomized controlled trials [RCTs] and subsequent large RCTs). Niacin may be considered as mono-therapy for patients intolerant of statins (SOR: B, one well-done RCT).Authors: Peter Lazzopina, MD; Anne Mounsey, MD University of North Carolina Family Medicine Residency, Chapel Hill; Lara Handler, MSLS University of North Carolina, Chapel Hil

Live and Online: Using Multiple Formats to Teach Users

Objective: To orient a large number of people to the new PubMed format, the Health Sciences Library needed creative approaches to traditional classroom instruction. The Library’s new approach was the use of offering three simultaneous class formats to help on and off campus users navigate the PubMed changes. Methods: The Health Sciences Library serves users from the Schools of Medicine, Nursing, Pharmacy, Dentistry, and Public Health, other university programs, and the general public. The increasing number of distance students as well as the growing preference for online formats prompted the Library to try offering multiple instructional formats. Classes were offered in three formats: dedicated online sessions in Adobe Connect, traditional in-person classes in the Library, and live streaming versions during the classes held in the Library. A post-class survey was used to determine the users’ evaluations of the instruction and the format via which it was offered, and registration statistics were gathered for class preference. This poster will examine the user response and satisfaction

Patron Satisfaction with Departmental Science Libraries at the University of North Carolina, Chapel Hill

This study focuses on the specialized needs of the graduate students served by departmental science libraries at The University of North Carolina at Chapel Hill. The aims were to learn how libraries can better meet the needs of graduate students served by the specialized science libraries, improve existing services, and determine what changes ought to be made in the future. An electronic survey was distributed to the entire graduate student population that is served by the science libraries. Results reveal the unmet needs of the students, the amount of interdisciplinary work and multi-library use by students, and the instructional services requested by the respondents. Recommendations for improvements and additions to existing library resources and services are given, as well as suggestions for future research on this topic

Can yoga reduce symptoms of anxiety and depression?

Q. Can yoga reduce symptoms of anxiety and depression? A. Yes, yoga can reduce symptoms of anxiety and depression (strength of recommendation [SOR]: B, systematic reviews of randomized controlled trials [RCTs] with significant heterogeneity). Across multiple RCTs using varied yoga interventions and diverse study populations, yoga typically improves overall symptom scores for anxiety and depression by about 40%, both by itself and as an adjunctive treatment. It produces no reported harmful side effects

Systematic review of mobile health behavioural interventions to improve uptake of HIV testing for vulnerable and key populations

This systematic narrative review examined the empirical evidence on the effectiveness of mobile health (mHealth) behavioral interventions designed to increase uptake of HIV testing among vulnerable and key populations

Capitalizing on Our Strengths to Improve the Public's Understanding of Health Information Through the Radio

Background: Health Sciences librarians at UNC Chapel Hill partner with producers of the YOUR HEALTH blog and radio show hosted by clinicians in the UNC Family Medicine Department. We helped develop the show’s interactive blog and continue to work with the show’s hosts and producer to improve website usability. Currently, HSL librarians are also improving and adding to consumer health information on the show’s blog

Non-publication of large randomized clinical trials: cross sectional analysis

Objective To estimate the frequency with which results of large randomized clinical trials registered with ClinicalTrials.gov are not available to the public.Design Cross sectional analysisSetting Trials with at least 500 participants that were prospectively registered with ClinicalTrials.gov and completed prior to January 2009.Data sources PubMed, Google Scholar, and Embase were searched to identify published manuscripts containing trial results. The final literature search occurred in November 2012. Registry entries for unpublished trials were reviewed to determine whether results for these studies were available in the ClinicalTrials.gov results database.Main outcome measures The frequency of non-publication of trial results and, among unpublished studies, the frequency with which results are unavailable in the ClinicalTrials.gov database.Results Of 585 registered trials, 171 (29%) remained unpublished. These 171 unpublished trials had an estimated total enrollment of 299 763 study participants. The median time between study completion and the final literature search was 60 months for unpublished trials. Non-publication was more common among trials that received industry funding (150/468, 32%) than those that did not (21/117, 18%), P=0.003. Of the 171 unpublished trials, 133 (78%) had no results available in ClinicalTrials.gov.Conclusions Among this group of large clinical trials, non-publication of results was common and the availability of results in the ClinicalTrials.gov database was limited. A substantial number of study participants were exposed to the risks of trial participation without the societal benefits that accompany the dissemination of trial results

Screening for convergence insufficiency using the CISS is not indicated in young adults

Aim This paper presents Convergence Insufficiency Symptom Survey (CISS) and orthoptic findings in a sample of typical young adults who considered themselves to have normal eyesight apart from weak spectacles. Methods The CISS questionnaire was administered,followed by a full orthoptic evaluation, to 167 university undergraduate and postgraduate students during the recruitment phase of another study. The primary criterion for recruitment to this study was that participants‘feltthey had normal eyesight'. A CISS score of ≥21 was used to define‘significant’symptoms, and convergence insufficiency (CI) was defined as convergence≥8cm from the nose with a fusion range <15Δ base-out with small or no exophoria. Results The group mean CISS score was 15.4. In all, 17(10%) of the participants were diagnosed with CI, but 11(65%) of these did not have significant symptoms. 41(25%) participants returned a‘high’CISS score of ≥21 but only 6 (15%) of these had genuine CI. Sensitivity of the CISS to detect CI in this asymptomatic sample was 38%; specificity 77%; positive predictive value 15%; and negative predictive value 92%. The area under a receiver operating characteristic curve was 0.596 (95% CI 0.46 to 0.73). Conclusions‘Visual symptoms’are common in young adults, but often not related to any clinical defect, while true CI may be asymptomatic. This study suggests that screening for CI is not indicate

Patient-Reported Outcome Instruments for Physical Symptoms Among Patients Receiving Maintenance Dialysis: A Systematic Review

Patients with end-stage renal disease (ESRD) receiving dialysis have poor health-related quality of life (HRQoL). Physical symptoms are highly prevalent among dialysis-dependent patients and play important roles in HRQoL. A range of symptom assessment tools have been used in dialysis-dependent patients, but there has been no previous systematic assessment of the existing symptom measures’ content, validity, and reliability