Natural Categorization: Electrophysiological Responses to Viewing Natural Versus Built Environments

Environments are unique in terms of structural composition and evoked human experience. Previous studies suggest that natural compared to built environments may increase positive emotions. Humans in natural environments also demonstrate greater performance on attention-based tasks. Few studies have investigated cortical mechanisms underlying these phenomena or probed these differences from a neural perspective. Using a temporally sensitive electrophysiological approach, we employ an event-related, implicit passive viewing task to demonstrate that in humans, a greater late positive potential (LPP) occurs with exposure to built than natural environments, resulting in a faster return of activation to pre-stimulus baseline levels when viewing natural environments. Our research thus provides new evidence suggesting natural environments are perceived differently from built environments, converging with previous behavioral findings and theoretical assumptions from environmental psychology

Short-acting β2-agonist prescription patterns for asthma management in the SABINA III primary care cohort

CKNOWLEDGEMENTS AstraZeneca funded all the SABINA studies and was involved in designing the study, developing the study protocol, conducting the study and performing the analyses. AstraZeneca was given the opportunity to review the manuscript before submission and funded medical writing support. Writing and editorial support was provided in accordance with Good Publication Practice (GPP3) guidelines (http://www.ismpp.org/gpp3) and fully funded by AstraZeneca.Peer reviewedPublisher PD

Caverns: Kentucky Middle School Poetry (Volume 1, 2018)

The editors of CAVERNS: Kentucky Middle School Poetry, volume 1, 2018, are extremely grateful to the talented students, dedicated teachers, and proud parents who made this first volume possible. Poems were solicited from classroom teachers during National Poetry Month, April 2017. The poems were selected for publication after extensive editorial board review, using a rubric adapted from Christine Lewy (2001). Only poems with signed parental/guardian permission letters were published. Students or parents decided whether to publish the poet’s full name or first name and last initial only. The poems were divided roughly into sections by topic: start-and-stop poems, homage, haiku, reflections, and ruminations. Future editions may have different sections. Support for the 2018 edition of CAVERNS: Kentucky Middle School Poetry was provided by the Kentucky Reading Association (KRA) and the Western Kentucky Reading Council of KRA

Ending the reign of short-acting β2-agonists in Australia?

Acknowledgements We would like to acknowledge and thank Steph James, Kiran Dhillon, Sophie Jones, Rob Campbell, Ying Liu, Marion Magee, Ondrej Rejda, Lisa Sugg, and Nicole O'Sullivan for their valuable contributions.Peer reviewe

Asthma exacerbation and steroid burden in Australian primary care

Peer reviewedPostprin

The association between short-acting β2-agonist over-prescription, and patient-reported acquisition and use on asthma control and exacerbations : data from Australia

Acknowledgements Author Contribution The authors meet criteria for authorship as recommended by the International Committee of Medical Journal Editors. All authors made a significant contribution to the work reported, whether that is in the conception, study design, execution, acquisition of data, analysis, and interpretation, or in all these areas. The first draft of the manuscript was written by Dr. Rebecca Vella and all authors took part in drafting, revising or critically reviewing the article. All authors gave final approval of the version to be published. All authors have agreed on the journal to which the article has been submitted and agree to be accountable for all aspects of the work. All authors have given approval for the submission of this article. The authors received no direct compensation related to the development of the manuscript. Funding This study was conducted by Optimum Patient Care Australia (OPCA) and was partially funded by AstraZeneca and Optimum Patient Care Australia (OPCA). The cost of the Open Access Fees were provided by AstraZeneca. No funding was received by the Observational & Pragmatic Research Institute Pte Ltd (OPRI) for its contribution.Peer reviewedPostprin

Corrigendum: Clinical Protocol for a Longitudinal Cohort Study Employing Systems Biology to Identify Markers of Vaccine Immunogenicity in Newborn Infants in The Gambia and Papua New Guinea.

[This corrects the article DOI: 10.3389/fped.2020.00197.]

Finishing the euchromatic sequence of the human genome

The sequence of the human genome encodes the genetic instructions for human physiology, as well as rich information about human evolution. In 2001, the International Human Genome Sequencing Consortium reported a draft sequence of the euchromatic portion of the human genome. Since then, the international collaboration has worked to convert this draft into a genome sequence with high accuracy and nearly complete coverage. Here, we report the result of this finishing process. The current genome sequence (Build 35) contains 2.85 billion nucleotides interrupted by only 341 gaps. It covers ∼99% of the euchromatic genome and is accurate to an error rate of ∼1 event per 100,000 bases. Many of the remaining euchromatic gaps are associated with segmental duplications and will require focused work with new methods. The near-complete sequence, the first for a vertebrate, greatly improves the precision of biological analyses of the human genome including studies of gene number, birth and death. Notably, the human enome seems to encode only 20,000-25,000 protein-coding genes. The genome sequence reported here should serve as a firm foundation for biomedical research in the decades ahead