Partial Deconfinement

We argue that the confined and deconfined phases in gauge theories are connected by a partially deconfined phase (i.e. SU(M) in SU(N), where M<N, is deconfined), which can be stable or unstable depending on the details of the theory. When this phase is unstable, it is the gauge theory counterpart of the small black hole phase in the dual string theory. Partial deconfinement is closely related to the Gross-Witten-Wadia transition, and is likely to be relevant to the QCD phase transition. The mechanism of partial deconfinement is related to a generic property of a class of systems. As an instructive example, we demonstrate the similarity between the Yang-Mills theory/string theory and a mathematical model of the collective behavior of ants [Beekman et al., Proceedings of the National Academy of Sciences, 2001]. By identifying the D-brane, open string and black hole with the ant, pheromone and ant trail, the dynamics of two systems closely resemble with each other, and qualitatively the same phase structures are obtained.Comment: 27 pages, many figures. v2: reference updated, minor improvements. v3: comments added. v4: version published in JHEP. A few comments and references added. v5: Normalization error in eq.(14) has been corrected, descriptions in Appendix B and Sec.3 have been corrected accordingly. A few footnotes and references have been adde

Cholecystokinin receptor antagonist, loxiglumide, inhibits invasiveness of human pancreatic cancer cell lines

AbstractRecently, cholecystokinin has been reported to be important in regulating the growth of pancreatic cancer. We investigated the effect of loxiglumide (LXG), a cholecytskinin receptor antagonist, on the invasiveness of two human pancreatic cancer cell lines. Cells were treated with LXG for 24 h, and examined in the invasion assay. The expression and activity of MMP-9 in supernatants from cancer cells were analyzed by Western blotting and zymogram. Interestingly, the invasiveness of cancer cells and expression of MMP-9 were decreased by LXG in a dose-dependent manner. LXG may be a useful therapeutic agent against pancreatic cancer

Partial Deconfinement

We argue that the confined and deconfined phases in gauge theories are connected by a partially deconfined phase (i.e. SU(M) in SU(N), where M < N, is deconfined), which can be stable or unstable depending on the details of the theory. When this phase is unstable, it is the gauge theory counterpart of the small black hole phase in the dual string theory. Partial deconfinement is closely related to the Gross-Witten-Wadia transition, and is likely to be relevant to the QCD phase transition.The mechanism of partial deconfinement is related to a generic property of a class of systems. As an instructive example, we demonstrate the similarity between the Yang-Mills theory/string theory and a mathematical model of the collective behavior of ants [Beekman et al., Proceedings of the National Academy of Sciences, 2001]. By identifying the D-brane, open string and black hole with the ant, pheromone and ant trail, the dynamics of two systems closely resemble with each other, and qualitatively the same phase structures are obtained

Testing a novel large-N reduction for N=4 super Yang-Mills theory on RxS^3

Recently a novel large-N reduction has been proposed as a maximally supersymmetric regularization of N=4 super Yang-Mills theory on RxS^3 in the planar limit. This proposal, if it works, will enable us to study the theory non-perturbatively on a computer, and hence to test the AdS/CFT correspondence analogously to the recent works on the D0-brane system. We provide a nontrivial check of this proposal by performing explicit calculations in the large-N reduced model, which is nothing but the so-called plane wave matrix model, around a particular stable vacuum corresponding to RxS^3. At finite temperature and at weak coupling, we reproduce precisely the deconfinement phase transition in the N=4 super Yang-Mills theory on RxS^3. This phase transition is considered to continue to the strongly coupled regime, where it corresponds to the Hawking-Page transition on the AdS side. We also perform calculations around other stable vacua, and reproduce the phase transition in super Yang-Mills theory on the corresponding curved space-times such as RxS^3/Z_q and RxS^2.Comment: 24 pages, 4 figure