Probing Transverse Momentum Broadening via Dihadron and Hadron-jet Angular Correlations in Relativistic Heavy-ion Collisions

Dijet, dihadron, hadron-jet angular correlations have been reckoned as important probes of the transverse momentum broadening effects in relativistic nuclear collisions. When a pair of high-energy jets created in hard collisions traverse the quark-gluon plasma produced in heavy-ion collisions, they become de-correlated due to the vacuum soft gluon radiation associated with the Sudakov logarithms and the medium-induced transverse momentum broadening. For the first time, we employ the systematical resummation formalism and establish a baseline calculation to describe the dihadron and hadron-jet angular correlation data in $pp$ and peripheral $AA$ collisions where the medium effect is negligible. We demonstrate that the medium-induced broadening $\langle p_\perp^2\rangle$ and the so-called jet quenching parameter $\hat q$ can be extracted from the angular de-correlations observed in $AA$ collisions. A global $\chi^2$ analysis of dihadron and hadron-jet angular correlation data renders the best fit $\langle p_\perp^2 \rangle \sim 13~\textrm{GeV}^2$ for a quark jet at RHIC top energy. Further experimental and theoretical efforts along the direction of this work shall significantly advance the quantitative understanding of transverse momentum broadening and help us acquire unprecedented knowledge of jet quenching parameter in relativistic heavy-ion collisions.Comment: 6 pages, 3 figure

Expanding CRISPR/Cas9 Genome Editing Capacity in Zebrafish Using SaCas9.

The type II CRISPR/Cas9 system has been used widely for genome editing in zebrafish. However, the requirement for the 5'-NGG-3' protospacer-adjacent motif (PAM) of Cas9 from Streptococcus pyogenes (SpCas9) limits its targeting sequences. Here, we report that a Cas9 ortholog from Staphylococcus aureus (SaCas9), and its KKH variant, successfully induced targeted mutagenesis with high frequency in zebrafish. Confirming previous findings, the SpCas9 variant, VQR, can also induce targeted mutations in zebrafish. Bioinformatics analysis of these new Cas targets suggests that the number of available target sites in the zebrafish genome can be greatly expanded. Collectively, the expanded target repertoire of Cas9 in zebrafish should further facilitate the utility of this organism for genetic studies of vertebrate biology

Fermentation and Redox Potential

Redox potential, known as oxidation–reduction or oxidoreduction potential (ORP), not only indicates the reduction and oxidation capacity of the environment but also reflects the metabolic activity of microorganisms. Redox potential can be monitored online and controlled in time for more efficient fermentation operation. This chapter reviews the enzymes that modulate intracellular redox potential, the genetically engineered strains that harbor specific redox potential–regulated genes, the approaches that were used to manipulate and control redox potential toward the production of desired metabolites, the role of redox potential in metabolic pathway, and the impact of redox potential on microbial physiology and metabolism. The application of redox potential–controlled ethanol fermentation and the development of three redox potential–controlled fermentation processes are illustrated. In the end, the future perspective of redox potential control is provided

Investigations on Performance of an Auto-Cascade Absorption Refrigeration System Operating with Mixed Refrigerants

Waste heat can be well utilized in absorption refrigeration systems. The auto-cascade absorption refrigeration system couldreach a lower temperature than traditional one because the non-azeotropic mixed refrigerants were used. In this paper, performances of an auto-cascade absorption refrigeration with R23/R134a/DMF (Dimethylformamide) as the working substance was analysed. Theoretical analysing results showed that, to some extent, the COP couldbe increased when the low pressure of the system decreased or the high pressure increased. The reasonable high pressure was the high turning point pressure, and reasonable low pressure was the low turning point pressure. The COP of the system monotonously increased with the increase of the mole fraction of R23. The lowest R23 mole fraction one should be the most promising