1,328 research outputs found
Muonium avoided level crossing measurement of electron spin relaxation rate in a series of substituted anthradithiophene based molecules
Muon spin spectroscopy and in particular the avoided level crossing technique is introduced, with the aim of showing it as a very sensitive local probe for electron spin relaxation in organic semiconductors. Avoided level crossing data on tert-butyl-ethynyl anthradithiophene, tri-methyl-silyl-ethynyl anthradithiophene and tri-ethygermyl-ethynyl anthradithiophene at different temperatures are presented. This series of molecules have an identical anthradithiophene backbone, but we have performed a targeted substitution on the central atom of the two side groups, of C, Si and Ge. We extracted the electron spin relaxation for the three molecules of this series and discuss them in the context of previously published results
The Hubble Space Telescope Extragalactic Distance Scale Key Project. X. The Cepheid Distance to NGC 7331
The distance to NGC 7331 has been derived from Cepheid variables observed
with HST/WFPC2, as part of the Extragalactic Distance Scale Key Project.
Multi-epoch exposures in F555W (V) and F814W (I), with photometry derived
independently from DoPHOT and DAOPHOT/ALLFRAME programs, were used to detect a
total of 13 reliable Cepheids, with periods between 11 and 42 days. The
relative distance moduli between NGC 7331 and the LMC, imply an extinction to
NGC 7331 of A_V = 0.47+-0.15 mag, and an extinction-corrected distance modulus
to NGC 7331 of 30.89+-0.14(random) mag, equivalent to a distance of 15.1 Mpc.
There are additional systematic uncertainties in the distance modulus of +-0.12
mag due to the calibration of the Cepheid Period-Luminosity relation, and a
systematic offset of +0.05+-0.04 mag if we applied the metallicity correction
inferred from the M101 results of Kennicutt et al 1998.Comment: To be published in The Astrophysical Journal, 1998 July 1, v501 note:
Figs 1 and 2 (JPEG files) and Fig 7 (multipage .eps file) need to be
viewed/printed separatel
The HST Key Project on the Extragalactic Distance Scale. XV. A Cepheid Distance to the Fornax Cluster and Its Implications
Using the Hubble Space Telescope (HST) 37 long-period Cepheid variables have
been discovered in the Fornax Cluster spiral galaxy NGC 1365. The resulting V
and I period-luminosity relations yield a true distance modulus of 31.35 +/-
0.07 mag, which corresponds to a distance of 18.6 +/- 0.6 Mpc. This measurement
provides several routes for estimating the Hubble Constant. (1) Assuming this
distance for the Fornax Cluster as a whole yields a local Hubble Constant of 70
+/-18_{random} [+/-7]_{systematic} km/s/Mpc. (2) Nine Cepheid-based distances
to groups of galaxies out to and including the Fornax and Virgo clusters yield
Ho = 73 (+/-16)_r [+/-7]_s km/s/Mpc. (3) Recalibrating the I-band Tully-Fisher
relation using NGC 1365 and six nearby spiral galaxies, and applying it to 15
galaxy clusters out to 100 Mpc gives Ho = 76 (+/-3)_r [+/-8]_s km/s/Mpc. (4)
Using a broad-based set of differential cluster distance moduli ranging from
Fornax to Abell 2147 gives Ho = 72 (+/-)_r [+/-6]_s km/s/Mpc. And finally, (5)
Assuming the NGC 1365 distance for the two additional Type Ia supernovae in
Fornax and adding them to the SnIa calibration (correcting for light curve
shape) gives Ho = 67 (+/-6)_r [+/-7]_s km/s/Mpc out to a distance in excess of
500 Mpc. All five of these Ho determinations agree to within their statistical
errors. The resulting estimate of the Hubble Constant combining all these
determinations is Ho = 72 (+/-5)_r [+/-12]_s km/s/Mpc.Comment: Accepted for publication in the Astrophysical Journal, Apr. 10 issue
28 pages, 3 tables, 12 figures (Correct figures and abstract
The HST Key Project on the Extragalactic Distance Scale XXVI. The Calibration of Population II Secondary Distance Indicators and the Value of the Hubble Constant
A Cepheid-based calibration is derived for four distance indicators that
utilize stars in the old stellar populations: the tip of the red giant branch
(TRGB), the planetary nebula luminosity function (PNLF), the globular cluster
luminosity function (GCLF) and the surface brightness fluctuation method (SBF).
The calibration is largely based on the Cepheid distances to 18 spiral galaxies
within cz =1500 km/s obtained as part of the HST Key Project on the
Extragalactic Distance Scale, but relies also on Cepheid distances from
separate HST and ground-based efforts. The newly derived calibration of the SBF
method is applied to obtain distances to four Abell clusters in the velocity
range between 3800 and 5000 km/s, observed by Lauer et al. (1998) using the
HST/WFPC2. Combined with cluster velocities corrected for a cosmological flow
model, these distances imply a value of the Hubble constant of H0 = 69 +/- 4
(random) +/- 6 (systematic) km/s/Mpc. This result assumes that the Cepheid PL
relation is independent of the metallicity of the variable stars; adopting a
metallicity correction as in Kennicutt et al. (1998), would produce a (5 +/-
3)% decrease in H0. Finally, the newly derived calibration allows us to
investigate systematics in the Cepheid, PNLF, SBF, GCLF and TRGB distance
scales.Comment: Accepted for publication in the Astrophysical Journal. 48 pages
(including 13 figures and 4 tables), plus two additional tables in landscape
format. Also available at http://astro.caltech.edu/~lff/pub.htm K' SBF
magnitudes have been update
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Design of the Subpopulations and Intermediate Outcome Measures in COPD (SPIROMICS) AIR Study.
IntroductionPopulation-based epidemiological evidence suggests that exposure to ambient air pollutants increases hospitalisations and mortality from chronic obstructive pulmonary disease (COPD), but less is known about the impact of exposure to air pollutants on patient-reported outcomes, morbidity and progression of COPD.Methods and analysisThe Subpopulations and Intermediate Outcome Measures in COPD (SPIROMICS) Air Pollution Study (SPIROMICS AIR) was initiated in 2013 to investigate the relation between individual-level estimates of short-term and long-term air pollution exposures, day-to-day symptom variability and disease progression in individuals with COPD. SPIROMICS AIR builds on a multicentre study of smokers with COPD, supplementing it with state-of-the-art air pollution exposure assessments of fine particulate matter, oxides of nitrogen, ozone, sulfur dioxide and black carbon. In the parent study, approximately 3000 smokers with and without airflow obstruction are being followed for up to 3 years for the identification of intermediate biomarkers which predict disease progression. Subcohorts undergo daily symptom monitoring using comprehensive daily diaries. The air monitoring and modelling methods employed in SPIROMICS AIR will provide estimates of individual exposure that incorporate residence-specific infiltration characteristics and participant-specific time-activity patterns. The overarching study aim is to understand the health effects of short-term and long-term exposures to air pollution on COPD morbidity, including exacerbation risk, patient-reported outcomes and disease progression.Ethics and disseminationThe institutional review boards of all the participating institutions approved the study protocols. The results of the trial will be presented at national and international meetings and published in peer-reviewed journals
Contributing factors to advanced brain aging in depression and anxiety disorders
Depression and anxiety are common and often comorbid mental health disorders that represent risk factors for aging-related conditions. Brain aging has shown to be more advanced in patients with major depressive disorder (MDD). Here, we extend prior work by investigating multivariate brain aging in patients with MDD, anxiety disorders, or both, and examine which factors contribute to older-appearing brains. Adults aged 18â57 years from the Netherlands Study of Depression and Anxiety underwent structural MRI. A pretrained brain-age prediction model based on >2000 samples from the ENIGMA consortium was applied to obtain brain-predicted age differences (brain PAD, predicted brain age minus chronological age) in 65 controls and 220 patients with current MDD and/or anxiety. Brain-PAD estimates were associated with clinical, somatic, lifestyle, and biological factors. After correcting for antidepressant use, brain PAD was significantly higher in MDD (+2.78 years, Cohenâs d = 0.25, 95% CI â0.10-0.60) and anxiety patients (+2.91 years, Cohenâs d = 0.27, 95% CI â0.08-0.61), compared with controls. There were no significant associations with lifestyle or biological stress systems. A multivariable model indicated unique contributions of higher severity of somatic depression symptoms (b = 4.21 years per unit increase on average sum score) and antidepressant use (â2.53 years) to brain PAD. Advanced brain aging in patients with MDD and anxiety was most strongly associated with somatic depressive symptomatology. We also present clinically relevant evidence for a potential neuroprotective antidepressant effect on the brain-PAD metric that requires follow-up in future research
The Hubble Space Telescope Key Project on the Extragalactic Distance Scale XXIV: The Calibration of Tully-Fisher Relations and the Value of the Hubble Constant
This paper presents the calibration of BVRIH$ Tully-Fisher relations based on
Cepheid distances to 21 galaxies within 25 Mpc, and 23 clusters within 10,000
km/s. These relations have been applied to several distant cluster surveys in
order to derive a value for the Hubble constant, H0, mainly concentrating on an
I-band all-sky survey by Giovanelli and collaborators which consisted of total
I magnitudes and 50% linewidth data for ~550 galaxies in 16 clusters. For
comparison, we also derive the values of H0 using surveys in B-band and V-band
by Bothun and collaborators, and in H-band by Aaronson and collaborators.
Careful comparisons with various other databases from literature suggest that
the H-band data, whose magnitudes are isophotal magnitudes extrapolated from
aperture magnitudes rather than total magnitudes, are subject to systematic
uncertainties. Taking a weighted average of the estimates of Hubble constants
from four surveys, we obtain H0 = 71 +- 4 (random) +- 7 (systematic) km/s/Mpc.
We have also investigated how various systematic uncertainties affect the value
of H0 such as the internal extinction correction method used, Tully-Fisher
slopes and shapes, a possible metallicity dependence of the Cepheid
period-luminosity relation and cluster population incompleteness bias.Comment: 34 pages, 13 figure
The Hubble Space Telescope Extragalactic Distance Scale Key Project XXIII. The Discovery of Cepheids In NGC 3319
The distance to NGC 3319 has been determined from Cepheid variable stars as
part of the Hubble Space Telescope Key Project on the Extragalactic Distance
Scale. Thirteen and four epochs of observations, using filters F555W (V) and
F814W (I) respectively, were made with the Wide Field Planetary Camera 2.
Thirty-three Cepheid variables between periods of 8 and 47 days were
discovered. Adopting a Large Magellanic Cloud distance modulus of 18.50 +- 0.10
mag and extinction of E(V-I)=0.13 mag, a true reddening-corrected distance
modulus (based on an analysis employing the ALLFRAME software package) of 30.78
+- 0.14 (random) +- 0.10 (systematic) mag and the extinction of E(V-I) = 0.06
mag were determined for NGC 3319. This galaxy is the last galaxy observed for
the HST H0 Key Project.Comment: 22 pages. A gzipped tar file containing 16 figures can be obtained
from http://www.ipac.caltech.edu/H0kp/n3319/n3319.htm
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