Word reading in monolingual and bilingual children with developmental language disorder

Many children with developmental language disorder (DLD) are reported to have word reading difficulties. However, previous research has focused mostly on monolingual children. The present study used two existing datasets to assess word reading outcomes of bilingual children with DLD. In Study 1, we compared word reading outcomes of monolingual and bilingual children with and without DLD (n = 93 monolingual DLD; n = 33 bilingual DLD, n = 42 monolingual TD; n = 74 bilingual TD). In Study 2, we compared those of monolingual (n = 91) and bilingual children with DLD (n = 51) on the basis of school record data. Findings from both studies show mean poor word reading outcomes and a high incidence of poor readers in the groups of children with DLD. Despite lower oral language outcomes of bilingual children in the mainstream language, reading outcomes of monolingual and bilingual children (with/without DLD) did not differ or outcomes were even better for the bilingual children. Overall, these findings indicate that DLD is a risk factor for word reading difficulties, while bilingualism is not

Disentangling the Grammar of 3-to 6-Year-Old Dutch Children With a Developmental Language Disorder

Purpose: Children with a developmental language disorder (DLD) are often delayed in their grammatical development. This is suggested to be the most important characteristic and clinical marker of DLD. However, it is unknown if this assumption is valid for young children, in the earliest stages of grammatical development. For this reason, this study investigates the complexity, diversity, and accuracy of the grammatical repertoires of 3-to 6-year-old Dutch children with DLD, in comparison to that of typically developing (TD) children matched on grammatical level. Method: Language samples of 59 children (29 children with DLD and 30 TD children) were analyzed using multiple measures of grammatical complexity, diversity, and accuracy. The TD children and children with DLD were language-matched on their grammatical development using the levels of the Dutch version of the Language Assessment, Remediation, and Screening Procedure, the Taal Analyse Remediëring en Screening Procedure (TARSP; Schlichting, 2017). Thus, the children with DLD were significantly older than the TD children (respectively DLD age range: 2;7–5;4 [years;months], Mage = 4;1; and TD age range: 2;0–3;9, Mage = 2;9). Results: The results show that children with DLD are comparable to language-matched TD children in their grammatical accuracy and diversity, but that they produce less complex utterances. Conclusions: The results indicate that children with DLD lag behind in their grammatical complexity as compared to language-matched TD children. The results also suggest that grammatical TARSP level is not sufficiently informative for selecting treatment goals. Instead, the results underline the importance of conducting language sample analyses, with special reference to the complexity of the utterances of a child with DLD

Predictors for grade 6 reading in children at familial risk of dyslexia

The present study investigates whether grade 6 reading outcomes, reading fluency, and reading comprehension can be predicted by grade 3 reading fluency, familial risk of dyslexia (FR), and grade 3 reading related skills: rapid automatized naming (RAN), phonological awareness (PA), and vocabulary. In a sample of 150 children, of whom 83 had a parent with dyslexia, correlation and regression analyses were performed. FR, measured on a continuous scale, was by itself related to all outcomes. However, FR did not explain any variance on top of grade 3 reading fluency. Grade 3 reading fluency strongly predicted grade 6 reading fluency and was also related to reading comprehension. RAN improved the prediction of grade 6 reading fluency, though the additional explained variance was small. Vocabulary and PA fully explained the variance that grade 3 reading fluency explained in grade 6 reading comprehension. Vocabulary explained a substantial amount of variance in grade 6 reading comprehension making it an interesting clinical target. As we used continuous measures of reading fluency and FR, our findings are not biased by distinct diagnostic criteria

Exploring relationships between teachers and students with diagnosed disabilities: A multi-informant approach

This study explored unique associations of student disabilities (ADHD, ASD, dyslexia) with teacher-, student- and peer-perceptions of student–teacher relationship quality. Sixty-three teachers, 510 students, and classmates from 24 Dutch mainstream elementary schools completed questionnaires about the student–teacher relationship quality. Teachers indicated whether students were diagnosed with disabilities. Multilevel models indicated that both teachers and classmates, but not students with ADHD themselves, reported higher levels of conflict in relationships. Additionally, teachers experienced less closeness and more conflict in relationships with children with ASD. The lower levels of closeness were also reported by classmates, but not by students with ASD themselves. Last, students with dyslexia experienced less closeness and conflict with their teacher, whereas their classmates and teachers reported more closeness and less conflict in relationships

Word reading in monolingual and bilingual children with Developmental Language Disorder Learning and Individual Differences

Many children with developmental language disorder (DLD) are reported to have word reading difficulties. However, previous research has focused mostly on monolingual children. The present study used two existing datasets to assess word reading outcomes of bilingual children with DLD. In Study 1, we compared word reading outcomes of monolingual and bilingual children with and without DLD (n = 93 monolingual DLD; n = 33 bilingual DLD, n = 42 monolingual TD; n = 74 bilingual TD). In Study 2, we compared those of monolingual (n = 91) and bilingual children with DLD (n = 51) on the basis of school record data. Findings from both studies show mean poor word reading outcomes and a high incidence of poor readers in the groups of children with DLD. Despite lower oral language outcomes of bilingual children in the mainstream language, reading outcomes of monolingual and bilingual children (with/without DLD) did not differ or outcomes were even better for the bilingual children. Overall, these findings indicate that DLD is a risk factor for word reading difficulties, while bilingualism is not

L1 and L2 reading skills in Dutch adolescents with a familial risk of dyslexia

Background. The present study investigated differences in reading and spelling outcomes in Dutch and English las a second language (ESL) in adolescents with a high familial risk of dyslexia, of whom some have developed dyslexia (HRDys) while others have not (HRnonDys), in comparison to a low familial risk control group without dyslexia (LRnonDys). This allowed us to investigate the persistence of dyslexia in the first language (L1) and the effect of dysleda on the second language (L2), which has, in this case, a lower orthographic transparency. Furthermore, the inclusion of the HRnonDys group allowed us to investigate the continuity of the familial risk of dyslexia, as previous studies observed that the HRnonDys group often scores in between the HRDys and LRnonDys group, and whether these readers without reading deficits in Dutch, have more reading difficulties in ESL. Methods. The data of three groups of adolescents were analyzed; 27 LRnonDys, 25 HRDys 25 HRnonDys. The mean age was 14;1 years; months, and 37 were male. All were native speakers lof Dutch, attended regular secondary education (grade 7 10), and were non-native speakers of English. Using MANOVA the groups were compared on Dutch and English word reading fluency (WRF), spelling and vocabulary, Dutch pseudoword and Iloanword reading fluency, phonological awareness (PA), rapid automatized naming (RAN), and verbal short term and working memory. A repeated measures ANOVA was used to compare English and Dutch WRF, spelling and vocabulary directly within the three groups. Results. The analyses revealed that the HRDys group had a deficit in both reading and spelling in Dutch and ESL. They also performed poorer than the LRnonDys group on all other measures. Effect sizes were especially large for pseudoword reading and the reaction times during the PA task. The HRnonDys group scored generally poorer than the LRnonDys group but this difference was only significant for Dutch pseudoword reading, PA reaction times and verbal short term memory. In general the HRDys and HRnonDys group scored similar in Dutch and English, except for English WRF where the HRDys group scored slightly better than expected based on their Dutch WRF. Discussion There was a high persistence of dyslexia. Adolescents with dyslexia ad large impairments in reading and spelling, and reading related measures, both in Dutch and ESL. Despite high inter-individual differences, an overall three-step pattern was observed. Adolescents in the HRnonDys group scored in between the HRDys and LRnonDys group, supporting the polygenetic origin of dyslexia and the continuity of the familial risk of dyslexia. The lower orthographic transparency did not have a negative effect on L2 reading, spelling and vocabulary, both in the HRnonDys and HRDys group. The latter group performed slightly better than expected in L2, which may be a result of the massive exposure to English and high motivation to use English by adolescents

Dichotic listening as an index of lateralization of speech perception in familial risk children with and without dyslexia

Atypical language lateralization has been marked as one of the factors that may contribute to the development of dyslexia. Indeed, atypical lateralization of linguistic functions such as speech processing in dyslexia has been demonstrated using neuroimaging studies, but also using the behavioral dichotic listening (DL) method. However, so far, DL results have been mixed. The current study assesses lateralization of speech processing by using DL in a sample of children at familial risk (FR) for dyslexia. In order to determine whether atypical lateralization of speech processing relates to reading ability, or is a correlate of being at familial risk, the current study compares the laterality index of FR children who did and did not become dyslexic, and a control group of readers without dyslexia. DL was tested in 3rd grade and in 5/6th grade. Results indicate that at both time points, all three groups have a right ear advantage, indicative of more pronounced left-hemispheric processing. However, the FR-dyslexic children are less good at reporting from the left ear than controls and FR-nondyslexic children. This impediment relates to reading fluency. (C) 2016 Elsevier Inc. All rights reserved

Paradoxical Benzodiazepine Response : A Rationale for Bumetanide in Neurodevelopmental Disorders?

The diuretic agent bumetanide has recently been put forward as a novel, promising treatment of behavioral symptoms in autism spectrum disorder (ASD) and related conditions. Bumetanide can decrease neuronal chloride concentrations and may thereby reinstate γ-aminobutyric acid (GABA)-ergic inhibition in patients with neurodevelopmental disorders. However, strategies to select appropriate candidates for bumetanide treatment are lacking. We hypothesized that a paradoxical response to GABA-enforcing agents such as benzodiazepines may predict the efficacy of bumetanide treatment in neurodevelopmental disorders. We describe a case of a 10-year-old girl with ASD, epilepsy, cortical dysplasia, and a 15q11.2 duplication who had exhibited marked behavioral arousal after previous treatment with clobazam, a benzodiazepine. We hypothesized that this response indicated the presence of depolarizing excitatory GABA and started bumetanide treatment with monitoring of behavior, cognition, and EEG. The treatment resulted in a marked clinical improvement in sensory behaviors, rigidity, and memory performance, which was substantiated by questionnaires and cognitive assessments. At baseline, the girl's EEG showed a depression in absolute α power, an electrographic sign previously related to ASD, which was normalized with bumetanide treatment. The effects of bumetanide on cognition and EEG seemed to mirror the "nonparadoxical" responses to benzodiazepines in healthy subjects. In addition, temporal lobe epilepsy and cortical dysplasia have both been linked to disturbed chloride homeostasis and seem to support our assumption that the observed paradoxical response was due to GABA-mediated excitation. This case highlights that a paradoxical behavioral response to GABA-enforcing drugs may constitute a framework for targeted treatment with bumetanide

Disentangling the Grammar of 3-to 6-Year-Old Dutch Children With a Developmental Language Disorder

Purpose: Children with a developmental language disorder (DLD) are often delayed in their grammatical development. This is suggested to be the most important characteristic and clinical marker of DLD. However, it is unknown if this assumption is valid for young children, in the earliest stages of grammatical development. For this reason, this study investigates the complexity, diversity, and accuracy of the grammatical repertoires of 3-to 6-year-old Dutch children with DLD, in comparison to that of typically developing (TD) children matched on grammatical level. Method: Language samples of 59 children (29 children with DLD and 30 TD children) were analyzed using multiple measures of grammatical complexity, diversity, and accuracy. The TD children and children with DLD were language-matched on their grammatical development using the levels of the Dutch version of the Language Assessment, Remediation, and Screening Procedure, the Taal Analyse Remediëring en Screening Procedure (TARSP; Schlichting, 2017). Thus, the children with DLD were significantly older than the TD children (respectively DLD age range: 2;7–5;4 [years;months], Mage = 4;1; and TD age range: 2;0–3;9, Mage = 2;9). Results: The results show that children with DLD are comparable to language-matched TD children in their grammatical accuracy and diversity, but that they produce less complex utterances. Conclusions: The results indicate that children with DLD lag behind in their grammatical complexity as compared to language-matched TD children. The results also suggest that grammatical TARSP level is not sufficiently informative for selecting treatment goals. Instead, the results underline the importance of conducting language sample analyses, with special reference to the complexity of the utterances of a child with DLD