173 research outputs found
Analysing the contagion effect and governance strategy of corporate financialisation based on a SIRS model
Recently, the phenomenon of economic ‘moving from reality to
virtual’ has attracted widespread attention. Based on the principle
of infectious disease dynamics, this study constructs a SIRS model
to examine the contagion effect of corporate financialisation.
Using Chinese manufacturing companies as samples, we verify
the contagion of corporate financialisation before performing a
simulation analysis and proposing strategies to address financial
contagion risks. The results shows that corporate financialisation
is contagious in the sample companies. This feature depends on
the initial contagion conditions and threshold. When the degree
of corporate financialisation does not meet the initial contagion
conditions and is within the contagion threshold, contagion will
not occur. Otherwise, financialisation behaviour will cause mutual
contagion and produce a contagious effect. Meanwhile, the
higher the contagion and the second conversion rates of financialisation, the stronger the contagion effect. The larger the financial reversal and self-recovery rates, the weaker the contagion
effect. Finally, we propose Multi-dimensional governance strategies of financial contagion risk. This study explores the formation
mechanism of corporate financialisation from a new perspective
to provide ideas for the financial governance of enterprises and
promote benign interaction between entities and finance
The Application of Three-Dimensional Collagen-Scaffolds Seeded with Myoblasts to Repair Skeletal Muscle Defects
Three-dimensional (3D) engineered tissue constructs are a novel and promising approach to tissue repair and regeneration. 3D tissue constructs have the ability to restore form and function to damaged soft tissue unlike previous methods, such as plastic surgery, which are able to restore only form, leaving the function of the soft tissue often compromised. In this study, we seeded murine myoblasts (C2C12) into a collagen composite scaffold and cultured the scaffold in a roller bottle cell culture system in order to create a 3D tissue graft in vitro. The 3D graft created in vitro was then utilized to investigate muscle tissue repair in vivo. The 3D muscle grafts were implanted into defect sites created in the skeletal muscles in mice. We detected that the scaffolds degraded slowly over time, and muscle healing was improved which was shown by an increased quantity of innervated and vascularized regenerated muscle fibers. Our results suggest that the collagen composite scaffold seeded with myoblasts can create a 3D muscle graft in vitro that can be employed for defect muscle tissue repair in vivo
Geometric, electronic properties and the thermodynamics of pure and Al--doped Li clusters
The first--principles density functional molecular dynamics simulations have
been carried out to investigate the geometric, the electronic, and the finite
temperature properties of pure Li clusters (Li, Li) and Al--doped
Li clusters (LiAl, LiAl). We find that addition of two Al
impurities in Li results in a substantial structural change, while the
addition of one Al impurity causes a rearrangement of atoms. Introduction of
Al--impurities in Li establishes a polar bond between Li and nearby Al
atom(s), leading to a multicentered bonding, which weakens the Li--Li metallic
bonds in the system. These weakened Li--Li bonds lead to a premelting feature
to occur at lower temperatures in Al--doped clusters. In LiAl, Al
atoms also form a weak covalent bond, resulting into their dimer like behavior.
This causes Al atoms not to `melt' till 800 K, in contrast to the Li atoms
which show a complete diffusive behavior above 400 K. Thus, although one Al
impurity in Li cluster does not change its melting characteristics
significantly, two impurities results in `surface melting' of Li atoms whose
motions are confined around Al dimer.Comment: 9 pages, 7 figure
Emerging Theranostic Nanomaterials in Diabetes and Its Complications
Diabetes mellitus (DM) refers to a group of metabolic disorders that are characterized by hyperglycemia. Oral subcutaneously administered antidiabetic drugs such as insulin, glipalamide, and metformin can temporarily balance blood sugar levels, however, long-term administration of these therapies is associated with undesirable side effects on the kidney and liver. In addition, due to overproduction of reactive oxygen species and hyperglycemia-induced macrovascular system damage, diabetics have an increased risk of complications. Fortunately, recent advances in nanomaterials have provided new opportunities for diabetes therapy and diagnosis. This review provides a panoramic overview of the current nanomaterials for the detection of diabetic biomarkers and diabetes treatment. Apart from diabetic sensing mechanisms and antidiabetic activities, the applications of these bioengineered nanoparticles for preventing several diabetic complications are elucidated. This review provides an overall perspective in this field, including current challenges and future trends, which may be helpful in informing the development of novel nanomaterials with new functions and properties for diabetes diagnosis and therapy.Peer reviewe
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