5,751 research outputs found
Getting research findings into practice : when to act on the evidence.
There is increasing interest in providing evidence based health care—that is, care in which healthcare professionals, provider managers, those who commission health care, the public, and policymakers consistently consider research evidence when making decisions. Purchasers, for example, should be able to influence the organisation and delivery of care (such as for cancer and stroke services) and the type and content of services (such as using chiropractic for back pain or dilatation and curettage and drug treatment for menorrhagia). Policymakers should ensure that policies on treatment reflect and are consistent with research evidence, and that the incentive structure within the health system promotes cost effective practice. They must also ensure that there is an adequate infrastructure for monitoring changes in practice and for producing, gathering, summarising, and disseminating evidence. Clinicians determine the day to day care patients receive in healthcare systems, and user groups (for example, patients, their families, and their representatives) are also beginning to play an important role in influencing healthcare decisions
Numerical Modelling of Instantaneous Plate Tectonics
Assuming lithospheric plates to be rigid, we systematically invert 68 spreading rates, 62 fracture zones trends and 10^6 earthquake slip vectors simultaneously to obtain a self-consistent model of instantaneous relative motions for eleven major plates. The inverse problem is linearized and solved iteratively by a maximum likelihood procedure. Because the uncertainties in the data are small, Gaussian statistics are shown to be adequate. The use of a linear theory permits (1) the calculation of the uncertainties in the various angular velocity vectors caused by uncertainties in the data, and (2) quantitative examination of the distribution of information within the data set.
The existence of a self-consistent model satisfying all the data is strong justification of the rigid plate assumption. Slow movement between North and South America is shown to be resolvable.
We then invert the trends of 20 linear island chains and aseismic ridges under the assumptions that they represent the directions of plate motions over a set of hot spots fixed with respect to each other. We conclude that these hot spots have had no significant relative motions in the last 10 My
Knot homology via derived categories of coherent sheaves II, sl(m) case
Using derived categories of equivariant coherent sheaves we construct a knot
homology theory which categorifies the quantum sl(m) knot polynomial. Our knot
homology naturally satisfies the categorified MOY relations and is
conjecturally isomorphic to Khovanov-Rozansky homology. Our construction is
motivated by the geometric Satake correspondence and is related to Manolescu's
by homological mirror symmetry.Comment: 51 pages, 9 figure
Herbal Product Use Among Anticoagulation Patients
Warfarin interacts with many conventional drug products and herbal products,1-3 Given the incompleteness of information on drug-herbal product interactions and the potential for health care practitioners to be unaware of their patients\u27 utilization of herbal products, we surveyed the use of such products among patients receiving warfarin through an anticoagulation clinic. Patients at the University of Maryland Medical System Anticoagulation Clinic were asked to complete an anonymous written questionnaire during their regularly scheduled appointments over one month
An approach to computing downward closures
The downward closure of a word language is the set of all (not necessarily
contiguous) subwords of its members. It is well-known that the downward closure
of any language is regular. While the downward closure appears to be a powerful
abstraction, algorithms for computing a finite automaton for the downward
closure of a given language have been established only for few language
classes.
This work presents a simple general method for computing downward closures.
For language classes that are closed under rational transductions, it is shown
that the computation of downward closures can be reduced to checking a certain
unboundedness property.
This result is used to prove that downward closures are computable for (i)
every language class with effectively semilinear Parikh images that are closed
under rational transductions, (ii) matrix languages, and (iii) indexed
languages (equivalently, languages accepted by higher-order pushdown automata
of order 2).Comment: Full version of contribution to ICALP 2015. Comments welcom
Star formation in the massive cluster merger Abell 2744
We present a comprehensive study of star-forming (SF) galaxies in the HST
Frontier Field recent cluster merger A2744 (z=0.308). Wide-field,
ultraviolet-infrared (UV-IR) imaging enables a direct constraint of the total
star formation rate (SFR) for 53 cluster galaxies, with SFR{UV+IR}=343+/-10
Msun/yr. Within the central 4 arcmin (1.1 Mpc) radius, the integrated SFR is
complete, yielding a total SFR{UV+IR}=201+/-9 Msun/yr. Focussing on obscured
star formation, this core region exhibits a total SFR{IR}=138+/-8 Msun/yr, a
mass-normalised SFR{IR} of Sigma{SFR}=11.2+/-0.7 Msun/yr per 10^14 Msun and a
fraction of IR-detected SF galaxies f{SF}=0.080(+0.010,-0.037). Overall, the
cluster population at z~0.3 exhibits significant intrinsic scatter in IR
properties (total SFR{IR}, Tdust distribution) apparently unrelated to the
dynamical state: A2744 is noticeably different to the merging Bullet cluster,
but similar to several relaxed clusters. However, in A2744 we identify a trail
of SF sources including jellyfish galaxies with substantial unobscured SF due
to extreme stripping (SFR{UV}/SFR{IR} up to 3.3). The orientation of the trail,
and of material stripped from constituent galaxies, indicates that the passing
shock front of the cluster merger was the trigger. Constraints on star
formation from both IR and UV are crucial for understanding galaxy evolution
within the densest environments.Comment: Accepted by MNRAS. 12 pages, 7 figures (high resolution versions of
Figs. 1 & 2 are available in the published PDF
Analysis of Bidirectional Associative Memory using SCSNA and Statistical Neurodynamics
Bidirectional associative memory (BAM) is a kind of an artificial neural
network used to memorize and retrieve heterogeneous pattern pairs. Many efforts
have been made to improve BAM from the the viewpoint of computer application,
and few theoretical studies have been done. We investigated the theoretical
characteristics of BAM using a framework of statistical-mechanical analysis. To
investigate the equilibrium state of BAM, we applied self-consistent signal to
noise analysis (SCSNA) and obtained a macroscopic parameter equations and
relative capacity. Moreover, to investigate not only the equilibrium state but
also the retrieval process of reaching the equilibrium state, we applied
statistical neurodynamics to the update rule of BAM and obtained evolution
equations for the macroscopic parameters. These evolution equations are
consistent with the results of SCSNA in the equilibrium state.Comment: 13 pages, 4 figure
Auto-calibration of ultrasonic lubricant-film thickness measurements
The measurement of oil film thickness in a lubricated component is essential information for performance monitoring and design. It is well established that such measurements can be made ultrasonically if the lubricant film is modelled as a collection of small springs. The ultrasonic method requires that component faces are separated and a reference reflection recorded in order to obtain a reflection coefficient value from which film thickness is calculated. The novel and practically useful approach put forward in this paper and validated experimentally allows reflection coefficient measurement without the requirement for a reference. This involves simultaneously measuring the amplitude and phase of an ultrasonic pulse reflected from a layer. Provided that the acoustic properties of the substrate are known, the theoretical relationship between the two can be fitted to the data in order to yield reflection coefficient amplitude and phase for an infinitely thick layer. This is equivalent to measuring a reference signal directly, but importantly does not require the materials to be separated. The further valuable aspect of this approach, which is demonstrated experimentally, is its ability to be used as a self-calibrating routine, inherently compensating for temperature effects. This is due to the relationship between the amplitude and phase being unaffected by changes in temperature which cause unwanted changes to the incident pulse. Finally, error analysis is performed showing how the accuracy of the results can be optimized. A finding of particular significance is the strong dependence of the accuracy of the technique on the amplitude of reflection coefficient input data used. This places some limitations on the applicability of the technique. © 2008 IOP Publishing Ltd
Effective Viscosity of Dilute Bacterial Suspensions: A Two-Dimensional Model
Suspensions of self-propelled particles are studied in the framework of
two-dimensional (2D) Stokesean hydrodynamics. A formula is obtained for the
effective viscosity of such suspensions in the limit of small concentrations.
This formula includes the two terms that are found in the 2D version of
Einstein's classical result for passive suspensions. To this, the main result
of the paper is added, an additional term due to self-propulsion which depends
on the physical and geometric properties of the active suspension. This term
explains the experimental observation of a decrease in effective viscosity in
active suspensions.Comment: 15 pages, 3 figures, submitted to Physical Biolog
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