The Puzzle of the Antebellum Fertility Decline in the United States: New Evidence and Reconsideration

All nations that can be characterized as developed have undergone the demographic transition from high to low levels of fertility and mortality. Most presently developed nations began their fertility transitions in the late nineteenth or early twentieth centuries. The United States was an exception. Evidence using census-based child-woman ratios suggests that the fertility of the white population of the United States was declining from at least the year 1800. By the end of the antebellum period in 1860, child-woman ratios had declined 33 percent. There is also indication that the free black population was experiencing a fertility transition. This transition was well in advance of significant urbanization, industrialization, and mortality decline and well in advance of every other presently developed nation with the exception of France. This paper uses census data on county-level child-woman ratios to test a variety of explanations on the antebellum American fertility transition. It also uses micro data from the IPUMS files for 1850 and 1860. A number of the explanations, including the land availability hypothesis, the local labor market-child default hypothesis, and the life cycle saving hypothesis, are consistent with the data, but nuptiality, not one of the usual explanations, emerges as likely very important.

American Indian Mortality in the Late Nineteenth Century: The Impact of Federal Assimilation Policies on a Vulnerable Population

Under the urging of late nineteenth-century humanitarian reformers, U.S. policy toward American Indians shifted from removal and relocation efforts to state-sponsored attempts to "civilize" Indians through allotment of tribal lands, citizenship, and forced education. There is little consensus, however, whether and to what extent federal assimilation efforts played a role in the stabilization and recovery of the American Indian population in the twentieth century. In this paper, we rely on a new IPUMS sample of the 1900 census of American Indians and census-based estimation methods to investigate the impact of federal assimilation policies on childhood mortality. We use children ever born and children surviving data included in the censuses to estimate childhood mortality and [responses to] several questions unique to the Indian enumeration [including tribal affiliation, degree of "white blood", type of dwelling, ability to speak English, and whether a citizen by allotment] to construct multivariate models of child mortality. The results suggest that mortality among American Indians in the late nineteenth century was very high - approximately 62% [standardize as % or percent throughout] higher than that for the white population. The impact of assimilation policies was mixed. Increased ability to speak English was associated with lower child mortality, while allotment of land in severalty was associated with higher mortality. The combined effect was a very modest four percent [as above] decline in mortality. As of 1900, the government campaign to assimilate Indians had yet to result in a significant decline in Indian mortality while incurring substantial economic and cultural costs.

The Construction of Life Tables for the American Indian Population at the Turn of the Twentieth Century

This paper constructs new life tables for the American Indian population in the late nineteenth and early nineteenth centuries, thus pushing back the availability of age-specific mortality and life expectancy estimates nearly half a century. Because of the lack of reliable vital registration data for the American Indian population in this period, the life tables are constructed using indirect census-based estimation methods. Infant and child mortality rates are estimated from the number of children ever born and children surviving reported by women in the 1900 and 1910 Indian censuses. Adult mortality rates are inferred from the infant and child mortality estimates using model life tables. Adult mortality rates are also estimated by applying the Preston-Bennett two-census method (1983) to the 1900-1910 intercensal period.

Serving GODAE Data and Products to the Ocean Community

The Global Ocean Data Assimilation Experiment (GODAE [http:// www.godae.org]) has spanned a decade of rapid technological development. The ever-increasing volume and diversity of oceanographic data produced by in situ instruments, remote-sensing platforms, and computer simulations have driven the development of a number of innovative technologies that are essential for connecting scientists with the data that they need. This paper gives an overview of the technologies that have been developed and applied in the course of GODAE, which now provide users of oceanographic data with the capability to discover, evaluate, visualize, download, and analyze data from all over the world. The key to this capability is the ability to reduce the inherent complexity of oceanographic data by providing a consistent, harmonized view of the various data products. The challenges of data serving have been addressed over the last 10 years through the cooperative skills and energies of many individuals

Directed differentiation of pluripotent cells to neural lineages: homogeneous formation and differentiation of a neurectoderm population

During embryogenesis the central and peripheral nervous systems arise from a neural precursor population, neurectoderm, formed during gastrulation. We demonstrate the differentiation of mouse embryonic stem cells to neurectoderm in culture, in a manner which recapitulates embryogenesis, with the sequential and homogeneous formation of primitive ectoderm, neural plate and neural tube. Formation of neurectoderm occurs in the absence of extraembryonic endoderm or mesoderm and results in a stratified epithelium of cells with morphology, gene expression and differentiation potential consistent with positionally unspecified neural tube. Differentiation of this population to homogeneous populations of neural crest or glia was also achieved. Neurectoderm formation in culture allows elucidation of signals involved in neural specification and generation of implantable cell populations for therapeutic use

Global health learning outcomes in pharmacy students completing international advanced pharmacy practice experiences

© 2020, American Association of Colleges of Pharmacy. All rights reserved. Objective. To examine the global health learning outcomes of Doctor of Pharmacy (PharmD) students from three US schools who participated in international advanced pharmacy practice experiences (APPEs). Methods. A mixed-methods, prospective study was used to assess fourth-year PharmD students at three US pharmacy schools who participated in an international APPE during the 2017-2018 academic year and a matched cohort (control group) of PharmD students who did not participate in an international APPE. To evaluate students’ self-perceived growth in the Consortium of Universities for Global Health (CUGH) competencies, all students completed a 13-item retrospective pre-post instrument using a five-point Likert scale. The students who had completed an international APPE were invited to participate in a focus group (N522). Paired and independent t tests and multiple linear regression were used to analyze data. Qualitative open-ended questions and focus group data were mapped to knowledge, skills, and attitudes themes. Results. The students who completed an international APPE (N581) showed significantly more growth in CUGH competencies than students who did not (mean improvement in total score of 10.3 [7.0] vs 2.4 [6.0]). International APPE participation was the only significant predictor of growth in CUGH competencies. The international APPE students reported improvements in cultural awareness and appreciation, communication skills, problem-solving skills, adaptability, self-awareness, personal and professional outlook, and global health perspective. Conclusion. Pharmacy students’ participation in international APPEs led to significant improvement in all CUGH competencies. The CUGH competency framework appears to be a suitable instrument to assess pharmacy students’ global health learning outcomes

Global health learning outcomes by country location and duration for international experiences

© 2020 American Association of Colleges of Pharmacy. Objective. To determine the impact of country income classification and experience duration on learning outcomes for student pharmacists participating in international advanced pharmacy practice experiences (APPEs). Methods. A mixed-methods, longitudinal study evaluated 81 fourth-year student pharmacists participating in an international APPE through one of three US universities. A pre-post survey was administered to evaluate students’ self-perceived growth across 13 competencies established by the Consortium of Universities for Global Health (CUGH). The survey included four additional open-ended questions. Student pharmacists were also invited to participate in a focus group. Paired and independent t tests and multiple linear regression were conducted. Qualitative survey and focus group data underwent a two-cycle, open-coding process using conventional content analysis. Results. Students who completed their APPE in a low-to middle-income country had greater growth in all CUGH competency statements compared to those who completed their APPE in a high-income country. Completing the APPE in a low-to middle-income country and prior travel for non-vacation purposes were significant predictors of student growth. Students who went to a low-to middle-income country demonstrated increased cultural sensitivity, more patient-centered care, and skill development, while students who went to a high-income country displayed increased knowledge regarding differ-ences in health care system components, pharmacy practice, pharmacy education, and an appreciation for alternative patient care approaches. Conclusion. Learning outcomes differed between students who completed an APPE in a high-income rather than a low-to middle-income country, with both types of locations providing valuable educational opportunities and professional and personal development