Timber composite floor beams under 2 years lon-term load

The long-term behaviour of composite beams is characterised by the response of its component parts (flanges and webs) to load, moisture content, temperature and relative humidity of the environment. This paper reports the results of a two years long-term test on two 6 m span composite floor beams made of laminated veneer lumber (LVL) under service load performed in an indoor, semi-controlled, and unheated environment. The environmental conditions were characterized by artificially induced cyclic air humidity with quasi-constant temperature. These conditions can be characterized as reasonably severe and presumably close to service class 3 according to Eurocode 5. During the test, the mid-span deflection, moisture content and air humidity were monitored. The paper recommends a creep factor for design of timber composite beams in severe environmental conditions

Type IIB Flows with N=1 Supersymmetry

We write general and explicit equations which solve the supersymmetry transformations with two arbitrary complex-proportional Weyl spinors on $\mathcal{N}=1$ supersymmetric type IIB strings backgrounds with all R-R $F_1$, $F_3$, $F_5$ and NS-NS $H_3$ fluxes turned on using SU(3) structures. The equations are generalizations of the ones found for specific relations between the two spinors by Grana, Minasian, Petrini and Tomasiello in [1] and by Butti, Grana, Minasian, Petrini and Zaffaroni in [2]. The general equations allow to study systematically generic type IIB backgrounds with $\mathcal{N}=1$ supersymmetry. We then explore some specific classes of flows with constant axion, flows with constant dilaton, flows on conformally Calabi-Yau backgrounds, flows with imaginary self-dual 3-form flux, flows with constant ratio of the two spinors, the corresponding equations are written down and some of their features and relations are discussed.Comment: 28 page

Computational studies on heterogenization of homogeneous catalyst of iron(III), nickel(II) and copper(II) N,N′-disalicylidene-1,2-phenylenediamine complex

Density functional theory (DFT) calculations were carried out on iron(III), nickel(II) and copper(II) complexes of N,N′-ethylenebis(salicylimine) both at molecular level (isolated complexes) and encapsulated in a zeolite framework to investigate changes that occur in their geometrical and electronic parameters as well as in their reactivity and stability. The computational results showed that the zeolite encapsulated metal complexes have higher reactivity and less stability as compared to the isolated metal complexes.               KEY WORDS: Density functional theory, N,N′-ethylenebis(salicylimine), Computational studies, Heterogenization, Electronic parameters Bull. Chem. Soc. Ethiop. 2019, 33(1), 91-102DOI: https://dx.doi.org/10.4314/bcse.v33i1.

N=1* model superpotential revisited (IR behaviour of N=4 limit)

The one-loop contribution to the superpotential, in particular the Veneziano-Yankielowicz potential in N=1 supersymmetric Yang-Mills model is discussed from an elementary field theory method and the matrix model point of view. Both approaches are based on the Renormalization Group variation of the superconformal N=4 supersymmetric Yang-Mills model.Comment: 31 page

Visceral leishmaniasis patients display altered composition and maturity of neutrophils as well as impaired neutrophil effector functions

Immunologically, active visceral leishmaniasis (VL) is characterised by profound immunosuppression, severe systemic inflammatory responses and an impaired capacity to control parasite replication. Neutrophils are highly versatile cells, which play a crucial role in the induction as well as the resolution of inflammation, the control of pathogen replication and the regulation of immune responses. Neutrophil functions have been investigated in human cutaneous leishmaniasis, however, their role in human visceral leishmaniasis is poorly understood. In the present study we evaluated the activation status and effector functions of neutrophils in patients with active VL and after successful anti-leishmanial treatment. Our results show that neutrophils are highly activated and have degranulated; high levels of arginase, myeloperoxidase and elastase, all contained in neutrophils’ granules, were found in the plasma of VL patients. In addition, we show that a large proportion of these cells are immature. We also analysed effector functions of neutrophils that are essential for pathogen clearance and show that neutrophils have an impaired capacity to release neutrophil extracellular traps, produce reactive oxygen species and phagocytose bacterial particles, but not Leishmania parasites. Our results suggest that impaired effector functions, increased activation and immaturity of neutrophils play a key role in the pathogenesis of VL

Exact Superpotentials, Theories with Flavor and Confining Vacua

In this paper we study some interesting properties of the effective superpotential of N=1 supersymmetric gauge theories with fundamental matter, with the help of the Dijkgraaf--Vafa proposal connecting supersymmetric gauge theories with matrix models. We find that the effective superpotential for theories with N_f fundamental flavors can be calculated in terms of quantities computed in the pure (N_f=0) gauge theory. Using this property we compute in a remarkably simple way the exact effective superpotential of N=1 supersymmetric theories with fundamental matter and gauge group SU(N_c), at the point in the moduli space where a maximal number of monopoles become massless (confining vacua). We extend the analysis to a generic point of the moduli space, and show how to compute the effective superpotential in this general case.Comment: 16 pages, no figure

High utility of active tuberculosis case finding in an Ethiopian prison

SETTING: Hawassa Prison, Southern Region of Ethiopia. OBJECTIVE: To determine the burden of pulmonary tuberculosis (TB) using active case finding among prisoners. DESIGN: In this cross-sectional study, prisoners were screened for TB using a symptom screen. Those with cough of 2 weeks had spot and morning sputum samples collected for acid-fast bacilli (AFB) smear microscopy and molecular diagnostic testing (Xpert® MTB/RIF). RESULTS: Among 2068 prisoners, 372 (18%) had a positive cough screen. The median age of these 372 persons was 23 years, 97% were male and 63% were from urban areas. Among those with a positive symptom screen, 8 (2%) were AFB sputum smear-positive and 31 (8%) were Xpert-positive. The point prevalence of pulmonary TB at the prison was 1748 per 100 000 persons. In multivariate analysis, persons with cough >4 weeks were more likely to have TB (OR 3.34, 95%CI 1.54–7.23). CONCLUSION: A high prevalence of TB was detected among inmates at a large Ethiopian prison. Active case finding using a cough symptom screen in combination with Xpert had high utility, and has the potential to interrupt transmission of Mycobacterium tuberculosis in correctional facilities in low- and middle-income, high-burden countries

Molecular epidemiology of tuberculosis in the Somali region, eastern Ethiopia

Background: Tuberculosis (TB) is one of the leading causes of morbidity and mortality in low-income countries like Ethiopia. However, because of the limited laboratory infrastructure there is a shortage of comprehensive data on the genotypes of clinical isolates of Mycobacterium tuberculosis (M. tuberculosis) complex (MTBC) in peripheral regions of Ethiopia. The objective of this study was to characterize MTBC isolates in the Somali region of eastern Ethiopia. Methods: A cross-sectional study was conducted in three health institutions between October 2018 and December 2019 in the capital of Somali region. A total of 323 MTBC isolates (249 from pulmonary TB and 74 from extrapulmonary TB) were analyzed using regions of difference 9 (RD 9)-based polymerase chain reaction (PCR) and spoligotyping. Results: Of the 323 MTBC isolates, 99.7% (95% CI: 99.1-100%) were M. tuberculosis while the remaining one isolate was M. bovis based on RD 9-based PCR. Spoligotyping identified 71 spoligotype patterns; 61 shared types and 10 orphans. A majority of the isolates were grouped in shared types while the remaining grouped in orphans. The M. tuberculosis lineages identified in this study were lineage 1, 2, 3, 4, and 7 with the percentages of 7.4, 2.2, 28.2, 60.4, and 0.6%, respectively. Most (87.9%) of the isolates were classified in clustered spoligotypes while the remaining 12.1% isolates were singletons. The predominant clustered spoligotypes identified were SIT 149, SIT 21, SIT 26, SIT 53, and SIT 52, each consisting of 17.6, 13.3, 8.4, 7.4, and 5%, respectively. Lineage 3 and lineage 4, as well as the age group (15-24), were associated significantly with clustering. Conclusion: The MTBC isolated from TB patients in Somali region were highly diverse, with considerable spoligotype clustering which suggests active TB transmission. In addition, the Beijing spoligotype was isolated in relatively higher frequency than the frequencies of its isolation from the other regions of Ethiopia warranting the attention of the TB Control Program of the Somali region

Duality Cascade in Brane Inflation

We show that brane inflation is very sensitive to tiny sharp features in extra dimensions, including those in the potential and in the warp factor. This can show up as observational signatures in the power spectrum and/or non-Gaussianities of the cosmic microwave background radiation (CMBR). One general example of such sharp features is a succession of small steps in a warped throat, caused by Seiberg duality cascade using gauge/gravity duality. We study the cosmological observational consequences of these steps in brane inflation. Since the steps come in a series, the prediction of other steps and their properties can be tested by future data and analysis. It is also possible that the steps are too close to be resolved in the power spectrum, in which case they may show up only in the non-Gaussianity of the CMB temperature fluctuations and/or EE polarization. We study two cases. In the slow-roll scenario where steps appear in the inflaton potential, the sensitivity of brane inflation to the height and width of the steps is increased by several orders of magnitude comparing to that in previously studied large field models. In the IR DBI scenario where steps appear in the warp factor, we find that the glitches in the power spectrum caused by these sharp features are generally small or even unobservable, but associated distinctive non-Gaussianity can be large. Together with its large negative running of the power spectrum index, this scenario clearly illustrates how rich and different a brane inflationary scenario can be when compared to generic slow-roll inflation. Such distinctive stringy features may provide a powerful probe of superstring theory.Comment: Corrections in Eq.(5.47), Eq (5.48), Eq(5.49) and Fig

Rational three-spin string duals and non-anomalous finite size effects

We determine by a one line computation the one-loop conformal dimension and the associated non-anomalous finite size correction for all operators dual to spinning strings of rational type having three angular momenta (J_1,J_2,J_3) on S^5. Finite size corrections are conjectured to encode information about string sigma model loop corrections to the spectrum of type IIB superstrings on AdS_5xS^5. We compare our result to the zero-mode contribution to the leading quantum string correction derived for the stable three-spin string with two out of the three spin labels identical and observe agreement. As a side result we clarify the relation between the Bethe root description of three-spin strings of the type (J,J',J') with respectively J>J' and J<J'.Comment: 15 pages, v2: comparison to string theory changed, references added, v3: textual modifications and title change