The burden of neglected tropical diseases in Ethiopia, and opportunities for integrated control and elimination

Background: Neglected tropical diseases (NTDs) are a group of chronic parasitic diseases and related conditions that are the most common diseases among the 2·7 billion people globally living on less than US$2 per day. In response to the growing challenge of NTDs, Ethiopia is preparing to launch a NTD Master Plan. The purpose of this review is to underscore the burden of NTDs in Ethiopia, highlight the state of current interventions, and suggest ways forward. Results: This review indicates that NTDs are significant public health problems in Ethiopia. From the analysis reported here, Ethiopia stands out for having the largest number of NTD cases following Nigeria and the Democratic Republic of Congo. Ethiopia is estimated to have the highest burden of trachoma, podoconiosis and cutaneous leishmaniasis in sub-Saharan Africa (SSA), the second highest burden in terms of ascariasis, leprosy and visceral leishmaniasis, and the third highest burden of hookworm. Infections such as schistosomiasis, trichuriasis, lymphatic filariasis and rabies are also common. A third of Ethiopians are infected with ascariasis, one quarter is infected with trichuriasis and one in eight Ethiopians lives with hookworm or is infected with trachoma. However, despite these high burdens of infection, the control of most NTDs in Ethiopia is in its infancy. In terms of NTD control achievements, Ethiopia reached the leprosy elimination target of 1 case/10,000 population in 1999. No cases of human African trypanosomiasis have been reported since 1984. Guinea worm eradication is in its final phase. The Onchocerciasis Control Program has been making steady progress since 2001. A national blindness survey was conducted in 2006 and the trachoma program has kicked off in some regions. Lymphatic Filariasis, podoconiosis and rabies mapping are underway. Conclusion: Ethiopia bears a significant burden of NTDs compared to other SSA countries. To achieve success in integrated control of NTDs, integrated mapping, rapid scale up of interventions and operational research into co implementation of intervention packages will be crucial

Assessing the impacts of land use/land cover changes on hydrological processes in Southern Ethiopia: The SWAT model approach

AbstractThe change in land use and land cover (LULC) due to human activities is a major cause of hydrological process changes in watersheds. This study assesses the effects of LULC changes on the hydrological processes in the Bilate catchment, located in southern Ethiopia. Landsat images of 1986, 2002, and 2018 were used to classify LULC through supervised classification. The Soil and Water Assessment Tool (SWAT) evaluated the hydrological responses to LULC changes. Results indicate an increase in built-up areas (0.70%), water bodies (0.19%), cultivated land (10.54%), and barren land (1.265%) from 1986 to 2018. Conversely, the forest (8.52%) and grazing (3.18%) areas declined. An increase in water leaving the root zone (962.02 mm/year), potential evapotranspiration (593.85 mm/year), actual evapotranspiration (201.71 mm/year), and surface runoff (514.86 mm/year) was observed, while soil water content (1423.25 mm/year) decreased at the catchment level. The declining soil water content and increasing actual and potential evapotranspiration could result in a water shortage for crop production. The impact of LULC changes on hydrology provides vital knowledge for integrated LULC and water resource management. Water resource development planning must consider LULC changes to achieve sustainable development in the catchment

Post COVID-19 vaccination side effects and associated factors among vaccinated health care providers in Oromia region, Ethiopia in 2021

Background Severe Acute Respiratory Syndrome (SARS COV-2) known as COVID-19 since its outbreak in 2019, more than 375 and 5.6 million were infected and dead, respectively. Its influence in all disciplines stimulated different industries to work day to night relentlessly to develop safe and effective vaccines to reduce the catastrophic effect of the disease. With the increasing number of people globally who have been vaccinated, the reports on possible adverse events have grown and gained great public attention. This study aims to determine post-COVID-19 vaccination adverse effects and associated factors among vaccinated Health care providers in the Oromia region, Ethiopia in 2021. Methods A cross-sectional study was conducted among 912 health care workers working in government hospitals in the central Oromia region from November 20 to December 15/2021. Respondents absent from work due to different reasons were excluded during the interview. The outcome variable was COVID-19 side effects (response as Yes/No). A descriptive analysis displayed findings in the form of the frequencies and percentages, and logistic regression was employed to see the association of different variables with side effects experienced. Result Overall, 92.1% of the participants experienced side effects either in 1st or 2nd doses of post-COVID-19 vaccination; 84.0% and (71.5%) of participants experienced at least one side effect in the 1st and 2nd dose of the vaccines, respectively. COVID-19 infection preventive protocols like keeping distance, hand wash using soap, wearing mask and using sanitizer were decreased post vaccination. About 74.3% of the respondents were worried about the adverse effects of the COVID-19 vaccine they received. The majority (80.2%) of the respondent felt fear while receiving the vaccine and 22.5% of the respondents suspect the effectiveness of the vaccine they took. About 14.8% of the vaccinated Health workers were infected by COVID-19 post-vaccination. Engaging in moderate physical activity and feeling fear when vaccinated were the independent factors associated with reported side effects of post-COVID-19 vaccination using multiple logistic regression. Respondents who did not engage in physical activity were 7.54 fold more likely to develop post-COVID-19 vaccination side effects compared to those who involved at least moderate-intensity physical activity[AOR = 7.54, 95% CI;2.46,23.12]. The odds of experiencing side effects among the respondents who felt fear when vaccinated were 10.73 times compared not felt fear (AOR = 10.73, 95% CI; 2.47,46.64), and similarly, those who felt little fear were 4.28 times more likely to experience side effects(AOR = 4.28, 95% CI; 1.28, 14.39). Conclusion Significant numbers of the respondents experienced side effects post COVID-19 vaccination. It is recommended to provide pre-awareness about the side effects to reduce observed anxiety related to the vaccine. It is also important to plan monitoring and evaluation of the post-vaccine effect using standard longitudinal study designs to measure the effects directly

Participants knowledge about COVID-19 Vaccine for the study of post COVID-19 vaccine evaluations in Oromia region, Ethiopia, 2021.

Participants knowledge about COVID-19 Vaccine for the study of post COVID-19 vaccine evaluations in Oromia region, Ethiopia, 2021.</p

Reasons not willing to take the 2nd dose of COVID-19 vaccine among health professionals for the study of post COVID-19 vaccine complication evaluations in central Oromia region, Ethiopia, 2021.

Reasons not willing to take the 2nd dose of COVID-19 vaccine among health professionals for the study of post COVID-19 vaccine complication evaluations in central Oromia region, Ethiopia, 2021.</p

Respondents practice to protect COVID-19 infections pre and post COVID-19 vaccination for the study of post COVID-19 vaccine evaluations in Oromia region, Ethiopia, 2021.

Respondents practice to protect COVID-19 infections pre and post COVID-19 vaccination for the study of post COVID-19 vaccine evaluations in Oromia region, Ethiopia, 2021.</p

Participants self-reported COVID-19 vaccine side effects for the study of post COVID-19 vaccine evaluations in Oromia region, Ethiopia, 2021.

Participants self-reported COVID-19 vaccine side effects for the study of post COVID-19 vaccine evaluations in Oromia region, Ethiopia, 2021.</p

Respondents COVID-19 infection status before the vaccination for the study of post COVID-19 vaccine evaluations in Oromia region, Ethiopia, 2021.

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Perceptions related to COVID-19 vaccine and Re-infection among participants for the study of COVID-19 Vaccine complication evaluations in central Oromia region, Ethiopia, 2021.

Perceptions related to COVID-19 vaccine and Re-infection among participants for the study of COVID-19 Vaccine complication evaluations in central Oromia region, Ethiopia, 2021.</p

Respondents behavioral factors for the study of post COVID-19 vaccine evaluations in Oromia region, Ethiopia, 2021.

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