Quantifying immediate price impact of trades based on the kk-shell decomposition of stock trading networks

Traders in a stock market exchange stock shares and form a stock trading network. Trades at different positions of the stock trading network may contain different information. We construct stock trading networks based on the limit order book data and classify traders into $k$ classes using the $k$-shell decomposition method. We investigate the influences of trading behaviors on the price impact by comparing a closed national market (A-shares) with an international market (B-shares), individuals and institutions, partially filled and filled trades, buyer-initiated and seller-initiated trades, and trades at different positions of a trading network. Institutional traders professionally use some trading strategies to reduce the price impact and individuals at the same positions in the trading network have a higher price impact than institutions. We also find that trades in the core have higher price impacts than those in the peripheral shell.Comment: 6 pages including 3 figures and 1 tabl

Peratic Phase Transition by Bulk-to-Surface Response

The study of dynamical phase transitions has been attracting considerable research efforts in the last decade. One theme of present interest is to search for exotic scenarios beyond the framework of equilibrium phase transitions. Here, we establish a duality between many-body dynamics and static Hamiltonian ground states for both classical and quantum systems. We construct frustration free Hamiltonians whose ground state phase transitions have rigorous duality to chaotic transitions in dynamical systems. By this duality, we show the corresponding ground state phase transitions are characterized by bulk-to-surface response, which are then dubbed "peratic" meaning defined by response to the boundary. For the classical system, we show how the time-like dimension emerges in the static ground states. For the quantum system, the ground state is a superposition of geometrical lines on a two dimensional array, which encode the dynamical Floquet evolution history of one dimensional disordered spin chains. Our prediction of peratic phase transition has direct consequences in quantum simulation platforms such as Rydberg atoms and superconducting qubits, as well as anisotropic spin glass materials. The discovery would shed light on the unification of dynamical phase transitions with equilibrium systems.Comment: 6+8 pages; 3+4 figure

Studies on some active components and antimicrobial activities of the fermentation broth of endophytic fungi DZY16 Isolated from Eucommia ulmoides Oliv.

Research into plant-derived endophytic fungi has grown in recent decades. Endophytic fungi still have enormous potential to inspire and influence modern agriculture. In this study, the endophytic fungi DZY16 isolated from Eucommia ulmoides Oliv. was tested for its bioactive components and antimicrobial activities using phenol-sulfuric acid method, high performance liquid chromatography method and growth inhibition measurements. The results show that variation trend of extracellular polysaccharide content at different growth stages of the strain DZY16 and the maximum content of extracellular polysaccharide was 2.02 g/L at the sixth day. Moreover, the fermentation broth of the DZY16 contained guanosine, uridine and adenosine; the contents were 1.54 mg/g, 1.07 mg/g and 1.36 mg/g respectively. On the other hand, the strongest antimicrobial activity was exhibited by the acetylacetate extract of strain DZY16 against Rhizoctonia solani and Gibberella zeae, showing 59.84 and 70.86% respectively. The strain DZY16 was identified by internal transcribed spacer (ITS) sequence as belonging to Nigrospora. The results indicate that the endophytic fungi DZY16 of the plant E. ulmoides Oliv. is a promising source of novel bioactive compounds.Keywords: Eucommia ulmoides Oliv., endophytic fungi, extracellular polysaccharide, nucleotides, antimicrobial activityAfrican Journal of Biotechnology Vol. 12(15), pp. 1862-186

Dexmedetomidine post-treatment attenuates cardiac ischaemia/reperfusion injury by inhibiting apoptosis through HIF-1α signalling.

Hypoxia-inducible factor 1α (HIF-1α) plays a critical role in the apoptotic process during cardiac ischaemia/reperfusion (I/R) injury. This study aimed to investigate whether post-treatment with dexmedetomidine (DEX) could protect against I/R-induced cardiac apoptosis in vivo and in vitro via regulating HIF-1α signalling pathway. Rat myocardial I/R was induced by occluding the left anterior descending artery for 30 minutes followed by 6-hours reperfusion, and cardiomyocyte hypoxia/reoxygenation (H/R) was induced by oxygen-glucose deprivation for 6 hours followed by 3-hours reoxygenation. Dexmedetomidine administration at the beginning of reperfusion or reoxygenation attenuated I/R-induced myocardial injury or H/R-induced cell death, alleviated mitochondrial dysfunction, reduced the number of apoptotic cardiomyocytes, inhibited the activation of HIF-1α and modulated the expressions of apoptosis-related proteins including BCL-2, BAX, BNIP3, cleaved caspase-3 and cleaved PARP. Conversely, the HIF-1α prolyl hydroxylase-2 inhibitor IOX2 partly blocked DEX-mediated cardioprotection both in vivo and in vitro. Mechanistically, DEX down-regulated HIF-1α expression at the post-transcriptional level and inhibited the transcriptional activation of the target gene BNIP3. Post-treatment with DEX protects against cardiac I/R injury in vivo and H/R injury in vitro. These effects are, at least in part, mediated via the inhibition of cell apoptosis by targeting HIF-1α signalling

All-pay Auction Based Profit Maximization in End-to-End Computation Offloading System

Pricing is an important issue in mobile edge computing. How to appropriately determine the bid of end user (EU) is an incentive factor for edge cloud (EC) to offer service. In this letter, we propose an equilibrium pricing scheme based on the all-pay auction model in end-to-end collaboration environment, wherein all EUs can acquire the service at a lower price than the own value of the required resource. In addition, we propose a set allocation algorithm to divide all the bidders into different sets according to the price, and the EUs in each set get the service, which averts the case of getting no service due to the low price. Extensive simulation results demonstrate that the proposed scheme can effectively maximize the total profit of the edge offloading system, and guarantee all EUs can access the service

Poly[[diaqua-μ6-succinato-di-μ5-succinato-didysprosium(III)] mono­hydrate]

The title compound, {[Dy2(C4H4O4)3(H2O)2]·H2O}n, is isostructural with other lanthanide succinates of the same formula. The DyIII atom is nine-coordinated in a tricapped trigonal–prismatic environment by eight O atoms, derived from six carboxyl­ate groups and a water mol­ecule. One of the independent succinate anions is located about a crystallographic inversion center and the uncoordinated water mol­ecule lies on a twofold axis. The crystal structure comprises edge-shared DyO9 polyhedra linked by succinate bridges, forming a three-dimensional network architecture. Intra- and inter­molecular O—H⋯O hydrogen bonds are present in the crystal structure

Increased serum myeloid-related protein 8/14 level is associated with atherosclerosis in type 2 diabetic patients

<p>Abstract</p> <p>Background</p> <p>Myeloid-related protein 8/14 (MRP8/14) is a stable heterodimer formed by two different calcium-binding proteins (MRP8 and MRP14). Studies have identified that MRP8/14 regulates vascular inflammation and serves as a novel marker of acute coronary syndrome. In this study, we evaluated the correlation between serum levels of MRP8/14, hsCRP, endogenous secretory receptor for advanced glycation end-products (esRAGE) and the occurrence of coronary artery disease (CAD), or carotid intima-media thickness (IMT) when CAD was not yet developed in diabetic patients.</p> <p>Methods</p> <p>Serum levels of MRP8/14, esRAGE and hsCRP were measured in 375 diabetic patients. Then the results of those who had CAD were compared against who had not. Also, we investigated the associations between above-mentioned indicators and IMT of subjects without CAD in both diabetic group and non-diabetic one.</p> <p>Results</p> <p>Serum MRP8/14 was significantly higher in CAD than in non-CAD group (9.7 ± 3.6 ug/ml vs. 8.2 ± 3.0 ug/ml, <it>P </it>< 0.001). It was associated with severity of CAD (<it>r </it>= 0.16, <it>P </it>= 0.026). In non-CAD group, MRP8/14 was associated with IMT in patients with (<it>r </it>= 0.30, <it>P </it>< 0.001) or without diabetes (<it>r </it>= 0.26, <it>P </it>= 0.015). The areas under the curves of receiver operating characteristic for CAD were 0.63 (95% CI 0.57-0.68) for MRP8/14, 0.76 (95% CI 0.71-0.81) for hsCRP and 0.62 (95% CI 0.56 -0.67) for esRAGE.</p> <p>Conclusion</p> <p>In summary, we report that diabetic patients with CAD had elevated plasma MRP8/14 levels which were also positively correlated with the severity of CAD and carotid IMT in patients without clinically overt CAD.</p