A Novel Discipline in Embryology — Animal Embryo Breeding

The modern animal biotechnologies, such as animal cloning, transgenesis, sex determination, stem cells, designing new livestock, must be performed on animal gametes including sperm and oocytes, and embryos based on embryology theory. Currently, some key biotechnologies in embryology have become the most powerful tool for animal scientists and breeders to improve genetic construction of animal herds. Here, authors put forward a new concept of Animal Embryo Breeding Science to describe this discipline formation, development, and application in animal genetic improvement and breeding. The relationship of embryo breeding with other disciplines has been profiled. Thus, animal scientists and breeders can easily understand and apply embryo breeding theory and related key techniques to accelerate animal improvement speed, to modify genetic construction of animal population, and to design and create new animal individual or breed

Three-dimensional numerical study of flow characteristic and membrane fouling evolution in an enzymatic membrane reactor

In order to enhance the understanding of membrane fouling mechanism, the hydrodynamics of granular flow in a stirred enzymatic membrane reactor was numerically investigated in the present study. A three-dimensional Euler-Euler model, coupled with k-e mixture turbulence model and drag function for interphase momentum exchange, was applied to simulate the two-phase (fluid-solid) turbulent flow. Numerical simulations of single- or two-phase turbulent flow under various stirring speed were implemented. The numerical results coincide very well with some published experimental data. Results for the distributions of velocity, shear stress and turbulent kinetic energy were provided. Our results show that the increase of stirring speed could not only enlarge the circulation loops in the reactor, but it can also increase the shear stress on the membrane surface and accelerate the mixing process of granular materials. The time evolution of volumetric function of granular materials on the membrane surface has qualitatively explained the evolution of membrane fouling.Comment: 10 panges, 8 figure

Analytic three-loop QCD corrections to top-quark and semileptonic b→ub\to u decays

We present the first analytic results of N$^3$LO QCD corrections to the top-quark decay width. We focus on the dominant leading color contribution, which includes light-quark loops. At NNLO, this dominant contribution accounts for 95% of the total correction. By utilizing the optical theorem, the N$^3$LO corrections are related to the imaginary parts of the four-loop self-energy Feynman diagrams, which are calculated with differential equations. The results are expressed in terms of harmonic polylogarithms, enabling fast and accurate evaluation. The third-order QCD corrections decrease the LO decay width by 0.667%, and the scale uncertainty is reduced by half compared to the NNLO result. The most precise prediction for the top-quark width is now 1.321 GeV for $m_t=172.69$ GeV. Additionally, we obtain the third-order QCD corrections to the dilepton invariant mass spectrum and decay width in the semileptonic $b\to u$ transition.Comment: 11 pages, 2 figure

Synchronous Gastric Carcinoma and Nodal Malignant Lymphoma: A Rare Case Report and Literature Review

Synchronous double malignancies of gastric carcinoma (GC) and malignant lymphoma (ML) are rare and very difficult to treat. We report a case of synchronous GC and nodal ML, regarding which clinical and pathological features and treatment are discussed. A 68-year-old woman with a history of inguinal hernia was admitted for abdominal pain and high fever and subsequently underwent herniorrhaphy, but the fever remained. Computerized tomography showed a stomach mass and multiple enlarged lymph nodes in the abdominal cavity and inguinal regions. Gastric adenocarcinoma coexistent with advanced in situ follicular lymphoma was confirmed by endoscopy, biopsy of inguinal lymph nodes and bone marrow examination. Two chemotherapy regimens, R-CHOP (rituximab, cyclophosphamide, perarubicin, vincristine and prednisone) and systemic therapy (5-fluorouracil and calcium folinate) combined with regional perfusion (oxaliplatin and etoposide) through the left gastric artery were performed at intervals against ML and GC, respectively. Partial remission in both tumors was achieved after 4 courses of treatment, but the patient finally died of heart failure. Scrupulous biopsy of non-draining lymph nodes in patients with gastrointestinal carcinomas is supposed to improve the diagnostic rate of simultaneous nodal ML. The interval chemotherapy strategy with two independent regimens is beneficial for such patients, especially for those unable to tolerate major surgery

2-(5-Bromo­pent­yl)-4-chloro-5-[2-(4-meth­oxy­phen­yl)ethyl­amino]­pyridazin-3(2H)-one

The asymmetric unit of the title compound, C18H23BrClN3O2, consists of two mol­ecules which exhibit different conformations of the pentyl chains [C—C—C—C torsion angles of −60.4 (4) and 175.8 (3)°]. The crysal packing exhibits a chain structure, generated through the O atom of the pyridazinone forming a hydrogen bond with the N—H group of an adjacent mol­ecule

Hematuria after Orthopedic Tuina: A Case Report and Brief Review of Literature

We present a case of a 24-year-old man who presented hematuria after the orthopedic tuina, which has not been recorded previously in the literature. We review complications of tuina in the literature too