3-[4-(Dimethyl­amino)benzyl­ideneamino]benzonitrile

The mol­ecule of the title Schiff base, C16H15N3, is non-planar and displays a trans configuration with respect to the C=N double bond. The two benzene rings make a dihedral angle of 49.24 (3)°

4-(2-Hydroxy­benzyl­idene­amino)­benzonitrile

The mol­ecule of the title compound, C14H10N2O, is nearly planar. There is a strong intra­molecular O—H⋯N hydrogen bond between the imine and hydr­oxy groups. The configuration with respect to the C=N double bond is anti (1E)

Bis[2-(3-cyano­phenyl­imino­meth­yl)phenolato]nickel(II)

In the title complex, [Ni(C14H9N2O)2], the NiII atom lies on an inversion center and is coordinated by the O atom and an N atom of two Schiff base 2-(3-cyano­phenyl­imino­meth­yl)phenolate ligands in a square-planar geometry. The dihedral angle between the cyano­phenyl and phenolate rings is 47.62 (7)°

Emotion Analysis of Telephone Complaints from Customer Based on Affective Computing

Customer complaint has been the important feedback for modern enterprises to improve their product and service quality as well as the customer’s loyalty. As one of the commonly used manners in customer complaint, telephone communication carries rich emotional information of speeches, which provides valuable resources for perceiving the customer’s satisfaction and studying the complaint handling skills. This paper studies the characteristics of telephone complaint speeches and proposes an analysis method based on affective computing technology, which can recognize the dynamic changes of customer emotions from the conversations between the service staff and the customer. The recognition process includes speaker recognition, emotional feature parameter extraction, and dynamic emotion recognition. Experimental results show that this method is effective and can reach high recognition rates of happy and angry states. It has been successfully applied to the operation quality and service administration in telecom and Internet service company

3-(2-Hydroxy­benzyl­ideneamino)benzonitrile

In the title mol­ecule, C14H10N2O, an intra­molecular O—H⋯N hydrogen bond contributes to the essential coplanarity of the two benzene rings, which form a dihedral angle of 6.04 (18)°

The NTSC VLBI System and its application in UT1 measurement

In order to measure the Universal Time (UT1) in real time, National Time Service Center (NTSC) has built a VGOS-like (VLBI Global Observing System) broadband VLBI network, which includes three 13-m radio telescopes located in Jilin, Sanya and Kashi, and a data analysis center in Xi'an. Each station is equipped with a highly stable hydrogen atomic clock and a self-developed VLBI backend, and is co-located with two GPS receivers. This VGOS-like VLBI network may play an important role in improving the Chinese broadband VLBI technology and making valuable contributions to domestic VLBI measurements of UT1. In this paper, we introduce the specifications of this VLBI network, and present the UT1 measurements at C-band conducted in 2018 using the Jilin-Kashi baseline of this network. The comparisons between our UT1 estimates and those provided by IERS suggest that the NTSC VLBI network is capable to determine UT1 accurate at the level of 58.8 microseconds

Long-term temporal dependence of droplets transiting through a fixed spatial point in gas-liquid twophase turbulent jets

We perform rescaled range analysis upon the signals measured by Dual Particle Dynamical Analyzer in gas-liquid two-phase turbulent jets. A novel rescaled range analysis is proposed to investigate these unevenly sampled signals. The Hurst exponents of velocity and other passive scalars in the bulk of spray are obtained to be 0.59$\pm$0.02 and the fractal dimension is hence 1.41$\pm$ 0.02, which are in remarkable agreement with and much more precise than previous results. These scaling exponents are found to be independent of the configuration and dimensions of the nozzle and the fluid flows. Therefore, such type of systems form a universality class with invariant scaling properties.Comment: 16 Elsart pages including 8 eps figure

Comparative Proteomic Approach Identifies Pkm2 and Cofilin-1 as Potential Diagnostic, Prognostic and Therapeutic Targets for Pulmonary Adenocarcinoma

Lung cancer is the leading cause of cancer-related death in the world. Non-small cell lung carcinomas (Non-SCLC) account for almost 80% of lung cancers, of which 40% were adenocarcinomas. For a better understanding of the molecular mechanisms behind the development and progression of lung cancer, particularly lung adenocarcinoma, we have used proteomics technology to search for candidate prognostic and therapeutic targets in pulmonary adenocarcinoma. The protein profile changes between human pulmonary adenocarcinoma tissue and paired surrounding normal tissue were analyzed using two-dimensional polyacrylamide gel electrophoresis (2-DE) based approach. Differentially expressed protein-spots were identified with ESI-Q-TOF MS/MS instruments. As a result, thirty two differentially expressed proteins (over 2-fold, p<0.05) were identified in pulmonary adenocarcinoma compared to normal tissues. Among them, two proteins (PKM2 and cofilin-1), significantly up-regulated in adenocarcinoma, were selected for detailed analysis. Immunohistochemical examination indicated that enhanced expression of PKM2 and cofilin-1 were correlated with the severity of epithelial dysplasia, as well as a relatively poor prognosis. Knockdown of PKM2 expression by RNA interference led to a significant suppression of cell growth and induction of apoptosis in pulmonary adenocarcinoma SPC-A1 cells in vitro, and tumor growth inhibition in vivo xenograft model (P<0.05). In addition, the shRNA expressing plasmid targeting cofilin-1 significantly inhibited tumor metastases and prolonged survival in LL/2 metastatic model. While additional works are needed to elucidate the biological significance and molecular mechanisms of these altered proteins identified in this study, PKM2 and cofilin-1 may serve as potential diagnostic and prognostic biomarkers, as well as therapeutic targets for pulmonary adenocarcinoma