Estimating the global root exudate carbon flux

Root exudation, the export of low-molecular weight organic carbon (C) from living plant roots to soil, influences microbial activity, nutrient availability, and ecosystem feedbacks to climate change, but the magnitude of this C flux at ecosystem and global scales is largely unknown. Here, we synthesize in situ measurements of root exudation rates and couple those to estimates of fine root biomass to estimate global and biome-level root exudate C fluxes. We estimate a global root exudate flux of 13.4 (10.1–20.2) Pg C y−1, or about 9% (7–14%) of global annual gross primary productivity. We did not find differences in root mass-specific exudation rates among biomes, though total exudate fluxes are estimated to be greatest in grasslands owing to their high density of absorptive root biomass. Our synthesis highlights the global importance of root exudates in the terrestrial C cycle and identifies regions where more in situ measurements are needed to improve future estimates of root exudate C fluxes

Detemir insulin for the treatment of diabetes mellitus in dogs

To investigate the effects of insulin detemir in dogs with diabetes mellitus

Survival time and prognostic factors in cats with newly diagnosed diabetes mellitus: 114 cases (2000-2009)

OBJECTIVE: To determine overall survival time and identify prognostic factors associated with survival time in cats with newly diagnosed diabetes mellitus. DESIGN: Retrospective case series. ANIMALS: 114 cats with newly diagnosed diabetes mellitus. PROCEDURES: Data for analysis included history, signalment, physical examination findings, hematologic and serum biochemical data, presence of ketoacidosis, and diagnosis of concurrent diseases at initial evaluation. The effects of possible predictors on survival time were determined by calculating hazard ratios (HRs) and 95% confidence intervals (CIs). RESULTS: Median survival time of diabetic cats was 516 days (range, 1 to 3,468 days); 70%, 64%, and 46% lived longer than 3, 6, and 24 months, respectively. Survival time was significantly shorter for cats with higher creatinine concentrations, with a hazard of dying approximately 5% greater for each increase of 10 μg/dL in serum creatinine concentration (adjusted HR, 1.005; 95% CI, 1.003 to 1.007). Ketoacidosis was not significantly associated with survival time (HR, 1.02; 95% CI, 0.590 to 1.78). CONCLUSIONS AND CLINICAL RELEVANCE: Cats with newly diagnosed diabetes mellitus had a fair to good prognosis. High serum creatinine concentration at diagnosis was associated with a poor outcome, likely because of the adverse effects of renal dysfunction. Ketoacidosis apparently was not associated with decreased survival time, suggesting that this complication should not necessarily be regarded as unfavorable

Detemir insulin for the treatment of diabetes mellitus in dogs

To investigate the effects of insulin detemir in dogs with diabetes mellitus

RESEARCH OF THE VRBJANSKA CHUKA SITE IN 2017. ИСТРАЖУВАЊЕ НА ЛОКАЛИТЕТОТ ВРБЈАНСКА ЧУКА ВО 2017 ГОДИНА.

The research of Vrbjanska Čuka in 2017 continued those started the previous season, but resulted in much more significant data regarding stratigraphy, architecture and economy in the Neolithic, Late Classical period and Middle Age. They were enabled by the multidisciplinary approach by implementing archaeobotany, zooarchaeology, geomagnetic scanning, digital topography, geoarchaeology, photogrammetry and 3D modeling of artifacts and the environment, drone orthophotography, isotopic, radiocarbon, lipid and use-wear analyses. All these components of the research of Vrbjanska Čuka enabled a comprehensive understanding of the Neolithic settlement and the community that lived there, that was the primary aim of this project. In regard to the stratigraphy of site, it has 5 horizons, the Neolithic ones being determined by architectural features and not by material culture. In this context, a further revision of Neolithic horizons is possible, upon extending the archaeological trench and making a detailed insight into the material culture and the architectural features that would arise. Even though ceramic vessels as the most frequent finds do not bear significant differences between Neolithic horizons in Vrbjanska Čuka, still it could be considered that, examined further, they could contribute towards an even more thorough understanding of changes of this settlement, but also within society. In this regard, radiocarbon analyses provide even a more detailed insight into the chronology of the settlement. According to the data obtained by these analyses at the University of Bern, the earliest Neolithic layers could be dated around 5900 BC. So far, this date places the site in the final phases of Early Neolithic, completely corresponding the dating of few other sites in Pelagonia. Analyzing samples from other Neolithic horizons would determine the chronology of the remaining Neolithic phases of the settlement, which, according to the architectural features, composes of three horizons. Such a stratigraphic condition could potentially be changed, unless there is a significant divergence within material culture and dating of the remaining two horizons. However, according to the current acknowledgment, despite not having an especially high stratigraphy (about 1 meter of the total tell height), this Neolithic settlement was especially dynamic during the 6th millennia BC. The tell was actively used for several hundreds of years during the Early Neolithic, only to be deserted in the next 5 000 years until Late Classical period. According to the material culture found in Horizons IV and V, activities at this site might have continued around the 4th and 5th centuries AD, with recorded activities around the 7th and 8th centuries, and then between the 10th and the 14th centuries

Research of the Vrbjanska Čuka site in 2017

[EN] The research of Vrbjanska Čuka in 2017 continued those started the previous season, but resulted in much more significant data regarding stratigraphy, architecture and economy in the Neolithic, Late Classical period and Middle Age. They were enabled by the multidisciplinary approach by implementing archaeobotany, zooarchaeology, geomagnetic scanning, digital topography, geoarchaeology, photogrammetry and 3D modeling of artifacts and the environment, drone orthophotography, isotopic, radiocarbon, lipid and use-wear analyses. All these components of the research of Vrbjanska Čuka enabled a comprehensive understanding of the Neolithic settlement and the community that lived there, that was the primary aim of this project. In regard to the stratigraphy of site, it has 5 horizons, the Neolithic ones being determined by architectural features and not by material culture. In this context, a further revision of Neolithic horizons is possible, upon extending the archaeological trench and making a detailed insight into the material culture and the architectural features that would arise. Even though ceramic vessels as the most frequent finds do not bear significant differences between Neolithic horizons in Vrbjanska Čuka, still it could be considered that, examined further, they could contribute towards an even more thorough understanding of changes of this settlement, but also within society. In this regard, radiocarbon analyses provide even a more detailed insight into the chronology of the settlement. According to the data obtained by these analyses at the University of Bern, the earliest Neolithic layers could be dated around 5900 BC. So far, this date places the site in the final phases of Early Neolithic, completely corresponding the dating of few other sites in Pelagonia. Analyzing samples from other Neolithic horizons would determine the chronology of the remaining Neolithic phases of the settlement, which, according to the architectural features, composes of three horizons. Such a stratigraphic condition could potentially be changed, unless there is a significant divergence within material culture and dating of the remaining two horizons. However, according to the current acknowledgment, despite not having an especially high stratigraphy (about 1 meter of the total tell height), this Neolithic settlement was especially dynamic during the 6th millennia BC. The tell was actively used for several hundreds of years during the Early Neolithic, only to be deserted in the next 5 000 years until Late Classical period. According to the material culture found in Horizons IV and V, activities at this site might have continued around the 4th and 5th centuries AD, with recorded activities around the 7th and 8th centuries, and then between the 10th and the 14th centuries.[RU] Истражувањата во 2017 година на локалитетот Врбјанска Чука кај Славеј, се надоврзаа на оние од претходната археолошка кампања, иако се добија многу позначајни податоци за стратиграфијата, архитектурата и стопанскиот живот во неолитот, доцната антика и средниот век. Тоа го овозможи мултидисциплинарниот пристап во истражувањата, коишто освен со елементарните методи и студии на наодите, се проучува и преку археоботаниката, археозоологијата, геомагнетното скенирање, дигиталната топографија, геоархеологијата, фотограметријата и 3Д моделирањето на артефактите и теренот, дронската ортофотографија, изотопските, радиокарбон и use-wear анализите, како и оние на липидите. Сите овие компоненти на истражувањето на Врбјанска Чука овозможуваат мошне доследно разбирање на неолитската населба и заедницата што живеела во неа, што воедно претставува и примарната цел на овој проект. Според добиените податоци од анализите, може да се заклучи дека неолитската населба е формирана околу 5900 година пр.н.е., односно при крајот на раниот неолит и имала 5 развојни фази. Според откриената материјална култура од подоцнежните хоризонти, може да се смета дека активностите на овој локалитет продолжиле околу III и IV век н.е., со регистрирани активности околу VII и VIII век, а потоа и во периодот меѓу X и XIV век.Peer reviewe

International Organizations Count

This special issue seeks to move forward the development of an empirical research agenda that takes seriously the complexity of how international organizations (IOs) function and the need to study that complexity at all levels of analysis by using robust research tools. We advocate for a broad empirical research approach that molds and sharpens theories about IOs by conducting systematic tests in large-sample environments. Two themes create a common thread throughout this issue. First, shifting the focus from whether IOs matter to how they work requires acknowledgment of the contingency of cause and effect. A second common thread lies in the authors' treatment of IO membership as an aggregate phenomenon—that is, as a set of institutions and relationships evolving over time and with many members rather than as a single organization. </jats:p