Transnational management-consulting firms in Thailand and ASEAN

The expansion and global role of management consulting services have become a topic of some interest in the context of the internationalization of services. The objectives, motivations, and strategies of Transnational management-Consulting Firms (TMCFs) in the Thai market is the core subject of this paper. In addition, this paper presents performance and operational aspects of TMCFs in Thailand. Since TMCFs may enter foreign markets through a number of entry modes, their entry mode preferences in this market are analyzed in the context of their objectives, and local and regional conditions. This analysis is based on a recently completed interview-based survey of TMCFs in Thailand and is therefore a timely examination of a crucial subject-especially given the ongoing debate about "Services and Development". Firm, home and host-country related and international factors are separately identified and their interactions discussed. The future prospects for TMCFs in Thailand and ASEAN are also discussed

Fear of getting Covid-19: A challenge to elective surgical practice and ways to overcome

Background: Covid-19, a global pandemic has a huge impact on surgical practice. There is transmission risk of Covid-19 during the elective surgery and nowadays it is a part of informed consent process. This has an impact on patient decision making as it creates anxiety and fear. Objective: To evaluate patient experience (fear of getting Covid-19) from elective surgery and challenges of elective surgical practice and ways to overcome during this pandemic era. Methods: This study was an observational cross-sectional survey and it has been conducted in General Surgery Department of Dr Akbar Niazi Teaching Hospital, Islamabad, from May to August 2021 after approval of Institutional Review Board (IRB). Participants for elective surgery and their negative report of Covid-19 infection by polymerase chain reaction (PCR) were included in the study. Fear of Covid-19 infection was measured through “fear of Covid-19 scale” by Ahorsu et al and analyzed. All findings were entered in a structured Proforma. Data was entered in SPSS version 26 and analyzed. Effect modifier chi square was used to find out the patient’s dropout due to getting Covid-19 infection from surgery. Results: Total 200 patients were included; 62% patients were male and 38% were females. The mean age of the patients was 38.64±12.08 years. The statistical analysis showed that there was a very significant association between FCV-19 scale and getting Covid-19 infection from elective surgeries (p ≤ 0.05). When stratified FCV-19 scale with education status of all patients there was a very significant association between them (p=0.001). The patient’s observations regarding FCV-19 questionnaire, most of the patients were disagreed (46.3%) to getting Covid-19 infection from their elective surgeries or any fear of Covid-19 infection. The actual dropout of patients from elective surgery due to fear of getting Covid-19 infection during surgery or staying in hospital was 7.5%. Conclusion: Fear of getting Covid-19 is still present in some of the patients who visit hospitals for elective surgeries. Discussing the various steps taken by the institute to improve patient safety and minimize risk of Covid-19, greatly enhanced their confidence in elective surgery and improved satisfaction level. Key words: Covid-19; Fear; Fear of Covid-19 Scale; Elective Surgical Procedures

Fear of getting Covid-19: A challenge to elective surgical practice and ways to overcome

Background: Covid-19, a global pandemic has a huge impact on surgical practice. There is transmission risk of Covid-19 during the elective surgery and nowadays it is a part of informed consent process. This has an impact on patient decision making as it creates anxiety and fear. Objective: To evaluate patient experience (fear of getting Covid-19) from elective surgery and challenges of elective surgical practice and ways to overcome during this pandemic era. Methods: This study was an observational cross-sectional survey and it has been conducted in General Surgery Department of Dr Akbar Niazi Teaching Hospital, Islamabad, from May to August 2021 after approval of Institutional Review Board (IRB). Participants for elective surgery and their negative report of Covid-19 infection by polymerase chain reaction (PCR) were included in the study. Fear of Covid-19 infection was measured through “fear of Covid-19 scale” by Ahorsu et al and analyzed. All findings were entered in a structured Proforma. Data was entered in SPSS version 26 and analyzed. Effect modifier chi square was used to find out the patient’s dropout due to getting Covid-19 infection from surgery. Results: Total 200 patients were included; 62% patients were male and 38% were females. The mean age of the patients was 38.64±12.08 years. The statistical analysis showed that there was a very significant association between FCV-19 scale and getting Covid-19 infection from elective surgeries (p ≤ 0.05). When stratified FCV-19 scale with education status of all patients there was a very significant association between them (p=0.001). The patient’s observations regarding FCV-19 questionnaire, most of the patients were disagreed (46.3%) to getting Covid-19 infection from their elective surgeries or any fear of Covid-19 infection. The actual dropout of patients from elective surgery due to fear of getting Covid-19 infection during surgery or staying in hospital was 7.5%. Conclusion: Fear of getting Covid-19 is still present in some of the patients who visit hospitals for elective surgeries. Discussing the various steps taken by the institute to improve patient safety and minimize risk of Covid-19, greatly enhanced their confidence in elective surgery and improved satisfaction level. Key words: Covid-19; Fear; Fear of Covid-19 Scale; Elective Surgical Procedures

Probiotics supplementation reduces cigarette smoke-induced damage in the respiratory micro-architecture of mice

This study evaluated the protective efficacy of probiotics supplementation against cigarette smoke-induced lung emphysema, inflammation, and loss of cilia in mice. Probiotics are known to promote mucosal tolerance and mitigate respiratory injuries. Twenty-four adult mice were randomly divided into three groups: control (Ctr), cigarette smoke (CS), and cigarette smoke + probiotics (CS+P). Probiotics were given for 7 days before exposure to smoke in the CS+P group. Tissue samples of the trachea (goblet cell count and index, loss of cilia), lungs (airspace distention), and bronchoalveolar lavage fluid (BALF) were collected and processed. The results showed a significant increase in acidic and neutral goblet cells in the CS group compared to the Ctr and CS+P groups (P < 0.05). Overall, goblet cell number and index were lower in the CS+P group (41.71 ± 5.76, 0.67 ± 0.073) than CS group (56.28 ± 5.34, 1.31 ± 0.28). Inflammatory cells and loss of cilia significantly decreased in mice fed probiotics before exposure to cigarette smoke (P < 0.05). Lung emphysema was also significantly reduced in the CS+P group compared to the CS group (P < 0.05). In conclusion, dietary supplementation of probiotics reduced lung emphysema, inflammatory cells, goblet cell index, and loss of cilia under conditions of cigarette smoke exposure in mice.O presente trabalho avaliou a eficácia da suplementação com probióticos contra a indução de enfisema, inflamação e perda de cílios por fumaça de cigarro em camundongos. Sabe-se que os probióticos promovem a tolerância da mucosa e mitigam as injúrias respiratórias. Vinte e quatro camundongos foram divididos, ao acaso, em três grupos: controle (CTR), fumaça de cigarro (CS) e fumaça de cigarro + probióticos (CS+P). Os probióticos foram fornecidos por sete dias antes da exposição à fumaça no grupo CS+P. Foram colhidas e processadas amostras de tecidos da traqueia (contagem de células caliciformes e index, perda de cílios), pulmões (distensão do espaço aéreo) e fluido de lavagem broncoalveolar. Os resultados obtidos revelaram um aumento significativo em células caliciformes acidificadas e neutralizadas no grupo CS quando comparado aos grupos Ctr e CS+P (P<0,05). Os números global e o índice de células caliciformes foram menores no grupo CS+P (41,71+ 5,76; 0,67+ 0,073) que no grupo CS (56,28+ 5,34 e 1,131+ 0,28). As células inflamatórias e a perda de cílios decresceram em camundongos alimentados com probióticos antes da exposição à fumaça de cigarro (P<0,05). O enfisema pulmonar também foi significativamente reduzido no grupo CS+P quando comparado ao grupo CS (P<0,05). A conclusão obtida foi que o fornecimento de dieta suplementada com probióticos reduziu o enfisema pulmonar, as células inflamatórias, o índice de células caliciformes e a perda de cílios nos camundongos expostos à fumaça de cigarro

Efficacy of mannan-oligosaccharide and live yeast feed additives on performance, rumen morphology, serum biochemical parameters and muscle morphometric characteristics in buffalo calves

The objective of the current study was to assess the effect of dietary supplementations of mannan-oligosaccharide, live yeast, and a combination of these two additives on growth performance, histo-morphology of the rumen, and muscle morphometric attributes in buffalo calves. A total of twenty buffalo calves (average weight of 25 kg) having 3 months of age were distributed according to a complete randomized design. All animals were individually stalled in the shed and were fed ad-libitum. Experimental animals were divided into four groups for 67 days: Control group(without the inclusion of dietary supplementation); MOS group (Mannan oligosaccharide 5 g/clave/day; Yeast group (Live yeast 2g/calve/day) and Mixed group (MOS + Live Yeast 2.5g + 1g )/calve/day. Experimental results revealed that combined supplementation of MOS and Yeast and MOS alone resulted in an increased number of short-chain fatty acids in the rumen as well as ruminal pH (P<0.05). Results showed a significant improvement in average daily gain and FCR of MOS and Mixed supplemented groups (P<0.05). Histomorphological evaluation of rumen mucosal epithelium showed a significant improvement in the mixed-supplemented group (P<0.05) as compared to the yeast-supplemented and control groups. Muscle quality parameters such as meat texture showed significant improvement in MOS and mix-supplemented groups. Histological examination of longissimus dorsi muscle cross-section showed a significantly higher(P<0.05) muscle fiber and muscle fascicle diameter in both MOS and mix-supplemented calves groups. In conclusion, the results of this experiment revealed that the dietary addition of MOS, Live yeast, and their combination have positive effects on growth performance, rumen histology indices, and muscle morphometric features in buffalo calves.Comment: Pages 13, 4 figure

Insect Pest Complex of Wheat Crop

Wheat Triticum aestivum L. is grown on broad range of climatic conditions because of edible grains, cereal crop and stable food of about 2 Billion peoples worldwide. Additionally, it is the rich source of carbohydrates (55–60%), vegetable proteins and contributed 50–60% daily dietary requirement in Pakistan. Globally, wheat crops is grown over 90% area of total cultivated area; facing devastating biotic and abiotic factors. The estimated economic losses in wheat quantity and quality are about 4 thousands per tonne per year including physical crop losses and handling. Economic losses of about 80–90 million USD in Pakistan are recorded due to inadequate production and handling losses. Wheat agro-ecosystem of the world colonizes many herbivore insects which are abundant and causing significant losses. The feeding style of the insects made them dispersive from one habitat to another imposing significant crop loss. Areas of maximum wheat production are encountered with either insect which chew the vegetative as well as reproductive part or stem and root feeders. This chapter provides the pest’s taxonomic rank, distribution across the globe, biology and damage of chewing and sucking insect pest of wheat. It is very important to study biology of the pest in accordance with crop cycle to forecast which insect stage is economically important, what the proper time to manage pest is and what type of control is necessary to manage crop pest. The chapter will provide management strategies well suited to pest stage and environment

CRP Gene Polymorphism and Their Risk Association With Type 2 Diabetes Mellitus

BACKGROUND: C-reactive protein (CRP) is an inflammatory marker associated with T2DM, obesity, insulin resistance, and cardiovascular disease. AIM: The present study evaluates the association of CRP +1059 G/C polymorphism of the CRP gene in 100 T2D cases and 100 healthy controls. METHODS: Present study was done by allele specific PCR method to study the CRP gene polymorphism in study subjects. RESULTS: Study found that CRP (+1059 G/C) genotype distribution among case and controls was found to be significant (p=0.001), Higher CRP C allele frequency (0.16) was observed compared to controls (0.04). CRP +1059 GC and CC had 2.72 (1.12-6.61), 20.56 (1.16-362.1) risk for T2D. It has been observed, HTN, Obesity, Smoking and alcoholism was found to be associated with increased risk of T2D, and a significant difference was observed in biochemical parameters. CONCLUSION: Study concluded that CRP gene polymorphism was found to be associated with risk of Type 2 Diabetes and risk was linked with heterozygosity and mutant homozygosity. Hypertension, Obesity, Smoking and alcoholism increases the risk of occurrence of Type 2 Diabetes

In-vitro Susceptibility of FMD Virus Serotype A Endemic in KPK, Pakistan

Foot and Mouth Disease virus (FMDV) serotype A is considered to be antigenic ally diverse among various geographical locations leading to diverse patterns of resistance and sensitivity. This phenomenon is posing high risks to global trade. This is the first study to quantify the effects of different physical factors (temperature, pH, UV and gamma irradiation) affecting the infectivity of FMDV serotype A.The infectivity of virus was calculated in term of tissue culture infectivity dose-50 (TCID-50) and plaque forming units (PFU). Virus in suspension (6×106 particles/ml) was treated using Cobalt-60 source in BHK-21 cell line grown in 96 well plates. The virus showed complete inactivation on 3, 5, 9 and 11 pH and 10kGy dose of gamma irradiations.The results revealed that increase in temperature (both moist and dry heat) and UV light as well as increase in time of exposure with same dose of UV irradiations significantly decreased the infectivity of virus (p&lt;0.05). These physical factors are a better alternate for virus inactivation than chemicals, which are toxic for the health and accumulate in the animal products. It is recommended that viral strains should be analyzed for their susceptibility to these physical methods. They could also be combined with thermal inactivation to further improve virus inactivity to obtain virus free products.