75 research outputs found
“Hot standards” for the thermoacidophilic archaeon Sulfolobus solfataricus
Within the archaea, the thermoacidophilic crenarchaeote Sulfolobus solfataricus has become an important model organism for physiology and biochemistry, comparative and functional genomics, as well as, more recently also for systems biology approaches. Within the Sulfolobus Systems Biology (“SulfoSYS”)-project the effect of changing growth temperatures on a metabolic network is investigated at the systems level by integrating genomic, transcriptomic, proteomic, metabolomic and enzymatic information for production of a silicon cell-model. The network under investigation is the central carbohydrate metabolism. The generation of high-quality quantitative data, which is critical for the investigation of biological systems and the successful integration of the different datasets, derived for example from high-throughput approaches (e.g., transcriptome or proteome analyses), requires the application and compliance of uniform standard protocols, e.g., for growth and handling of the organism as well as the “–omics” approaches. Here, we report on the establishment and implementation of standard operating procedures for the different wet-lab and in silico techniques that are applied within the SulfoSYS-project and that we believe can be useful for future projects on Sulfolobus or (hyper)thermophiles in general. Beside established techniques, it includes new methodologies like strain surveillance, the improved identification of membrane proteins and the application of crenarchaeal metabolomics
Rezension zu: Johannes Liebrecht, Fritz Kern und das gute alte Recht, Geistesgeschichte als neuer Zugang für die Mediävistik
Eingemauert in der Pyramide
Rezensiertes Werk:Susanne Schmidt-Radefeldt, Carl Friedrich von Gerber (1823–1891) und die Wissenschaft des deutschen Privatrechts (Schriften zur Rechtsgeschichte, Bd. 105), Berlin: Duncker & Humblot 2003, 308 S., ISBN 3-428-10422-
Rezension zu: Schirmer, Jakob, Die Göttinger Hegel-Schule. Julius Binder, Karl Larenz, Martin Busse, Gerhard Dulckeit und der juristische Neuhegelianismus in den 1930er Jahren (= Europäische Hochschulschriften, Reihe II Rechtswissenschaft 5867)
Naturrecht und Historische Rechtsschule
Symposion aus Anlass des 75. Geburtstages von Klaus Lui
Bona fides, good faith, aequitas and politics in 20th century Germany
Faculté de droit et de science politique de Montpellier, May16-18, 201
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