Rapport de Recherche-Action Education aux Médias et à l’Information

info:eu-repo/semantics/publishe

Equal IgG antibody response to pneumococcal vaccination in all stages of human immunodeficiency virus disease.

To evaluate the immunogenicity and safety of a 23-valent pneumococcal vaccine in human immunodeficiency virus (HIV)-seropositive patients, 80 men and 18 women received 1 dose of the vaccine (Pneumo 23; Pasteur Mérieux MSD, Brussels). The total IgG antibody response against all 23 Streptococcus pneumoniae capsular antigens was measured. Antibody levels were expressed in arbitrary units per microliter, referring to a standard curve. Geometric mean titers of the total IgG capsular antibodies on the day of vaccination and 30-45 days later were compared. The ratios of titers after and before vaccination in patients with > 500, 200-500, and < 200 CD4 lymphocytes/microL were 10, 10, and 12.6, respectively. Nonresponse (ratio < 4) occurred in 17% of patients and was unrelated to CD4 cell count. The vaccine was well tolerated; no serious side effects occurred. In 83% of the patients with HIV infection, the total antipneumococcal IgG level was higher after vaccination.Journal ArticleSCOPUS: ar.jinfo:eu-repo/semantics/publishe

Schijn bedriegt

Hoewel er verschillende maatregelen zijn (voor)genomen om schijnhuwelijken en relaties te voorkomen en bestrijden, is er weinig zicht op de mate waarin dit type relatie in Nederland voorkomt en wat de verschijningsvormen zijn. Dit exploratieve onderzoek zal een inventarisatie opleveren van de situatie in Nederland ten aanzien van schijnhuwelijken. Het dient een indicatie/schatting te geven over hoe vaak er sprake is van (mogelijke) schijnhuwelijken in Nederland en inzicht te verschaffen in verschillende verschijningsvormen van schijnhuwelijken en schijnrelaties. INHOUD: 1. Inleiding 2. Schijnrelaties: definities, beoordeling en verschijningsvormen 3. Het aandeel schijnrelaties in Nederland geschat op basis van relatiebreukcijfers 4. Schijnrelaties volgens beoordeling van de IND 5. Conclusie

Equal IgG antibody response to pneumococcal vaccination in all stages of human immunodeficiency virus disease

To evaluate the immunogenicity and safety of a 23-valent pneumococcal vaccine in human immunodeficiency virus (HIV)-seropositive patients, 80 men and 18 women received 1 dose of the vaccine (Pneumo 23; Pasteur Merieux MSD, Brussels), The total IgG antibody response against all 23 Streptococcus pneumoniae capsular antigens was measured. Antibody levels were expressed in arbitrary units per microliter, referring to a standard curve. Geometric mean titers of the total IgG capsular antibodies on the day of vaccination and 30-45 days later were compared. The ratios of titers after and before vaccination in patients with >500, 200-500, and <200 CD4 lymphocytes/mu L were 10, 10, and 12.6, respectively, Nonresponse (ratio <4) occurred in 17% of patients and was unrelated to CD4 cell count. The vaccine was well tolerated; no serious side effects occurred. In 83% of the patients with MV infection, the total antipneumococcal IgG level was higher after vaccination