Monitoring and evaluating business mentoring: towards a research and evaluation toolkit to measure impact

This paper presents a Research and Evaluation Toolkit (RET) which has applicability to mentoring programmes in all sectors and organizational contexts. The RET offers a practical guide for human resource development practitioners engaged in evaluation of learning and development programmes and more specifically, mentoring. The RET was a key outcome of a global 2.5-year impact evaluation project with Youth Business International and Middlesex University Business School, evaluating the impact of volunteer business mentoring on under-served young entrepreneurs and their business ventures. This paper brings to the forefront the importance of integrating a measurement and evaluation strategy from the initial mentoring programme design phase and ongoing management. Despite the growing number of survey reports and studies that highlight the importance of this aspect of mentoring programme design and management, measurement and evaluation continues to be one of the most challenging areas. As such, this paper contributes to our understanding concerning the role and effectiveness of ongoing monitoring and evaluation in relation to demonstrating the impact of human resource development interventions and provides a practical approach for practitioners to develop and enhance their evaluation strategy and methods. Key words: research and evaluation, business mentoring, impac

A Model To Measure Supination And Pronation Of The Foot Over Different Levels Of Physiological Stress Using An In-Shoe Force Monitoring System

The purpose of this study was to create a diagnostic model of supination and pronation of the foot using vertical ground reaction forces. A size adjustable capacitive transducer retaining 960 individual pressure cells was used to assess orthopaedic parameters of gait cyale timing and vertical ground reaction forces. A pilot sample of five males were used for this model. The subjects were exposed to six experimental conditions. These being; a) a walk, b) jog, c) walk on treadmill, and d) three levels of perceived exertion (mild, moderate and hard running). Perceived exertion was measured with the Borg (RPE) scale. All subjects were measured in the same brand of athletic shoe to control for intershoe differences. The ptonation/supination model was determined by medial/lateral force and timing measurements of the calcaneus, forefoot prominence, arch, the first and fifth metatarsal heads and the toe off (end of gait cycle). Results indicated bi-Iateral differences in the medial and lateral force measurements of the calcaneus. Timing in this area was slightly different. Medial to lateral timing pronation was evidenced in the treadmill walking and moderate running condition. As well, the loading of the first and fifth metatarsal heads as a percentage of the gait cycle did not change over the running conditions. The preliminary results of five subjects provides for limited support of a vertical ground reaction model to assess pronation and supination. Further research with techniques such as high speed photography will allow for clarification of this model

DYNAMIC MEASUREMENT OF FORCE WITHIN THE SHOE DURING CONDITIONS OF PERCEIVED EXERTION

INTRODUCTION Athletics and recreation are becoming a very large component of modem day society. Now, more than ever, more people are becoming very active and involved in recreational pursuits that include aerobics and running/jogging. The resultant increase in activity has lead to a noted increase in injuries (Nigg, 1985; Mckenzie et al., 1985). James et al (cited in Cavanagh, 1990), in a study of 180 injured runners identified three categories of running injury problem areas. These areas being: a) training errors; b)anatomic factors (biomechanics); and c) shoes and surfaces. Two thirds of these injuries were accounted for by training errors (increased mileage or increased intensity). Training errors concerning sudden increases in mileage or intensity tend to subject the body to new or greater than expected physiological stressors. Voloshin and Wosk (1981), have investigated the relationship between heel strike shock wave transmission and joint degeneration in walking subjects. Taken one step further, the implications of damage to the muscle-skeletal system by running is noted by Cavanagh (1990). This combined with the Nigg et al. (1983) data that suggests a relationship between the hardness of the athletic (running) surface and the incidence of injury has serious implications for the recreational runner/athlete. Clarke et al. (1985) have highlighted the possible injurious force involved in tibial accelerations that are the result of the runner taking longer strides. Since most people retain a constant stride frequency, as velocity increases, the athlete tends to increase their stride length. The resultant increase in stride length increases impact forces at the joint. This combined with the increase of ground reaction forces with higher running speeds (Munro et al., 1987) identifies high impact forces as a major factor to be considered when investigating the causal nature of running injuries. Research into the type of shoe and ground reaction forces has been equivocal. Nigg and Bahlsen (1988) have stated that shoes with the hardest mid soles elicit the lowest maximal vertical forces. Conversely other research has indicated that shoe hardness is related to higher (vertical) loading rates. Listed above are a number of factors involved in the prediction of running injuries. Further research is needed to discover the causative factors involved in etiology of sport medicine running injuries. An analysis of running shoes, in particular the vertical ground reaction forces, may account for dynamic patterns of gait. Running at different levels of perceived exertion may elicit clues as to the biomechanics patterns that may be injurious to runners. For example, the gait of a runner at the beginning of the run may be markedly different from the gait at the end of the run. Variables such as intensity and distance will greatly affect the athlete's form as they become more tired. Thus, the number of running injuries (2/3 of Clarke's population) as a result of improper training may be the function of bad form (gait mechanics). An analysis under different levels of exertion will identify patterns of pressure with the foot that may have implications for the construction and design of athletic footwear as well as training methods for runners. This study was an attempt to understand the dynamic of in-shoe vertical ground reaction forces within the shoe under differing levels of perceived exertion. Research in the area of running shoe forces may lead to the development of a better product that will decrease the rate and type of running injuries

Mouse Intestine Selects Nonmotile \u3cem\u3eflhDC\u3c/em\u3e Mutants of \u3cem\u3eEscherichia coli\u3c/em\u3e MG1655 with Increased Colonizing Ability and Better Utilization of Carbon Sources

d-Gluconate which is primarily catabolized via the Entner-Doudoroff (ED) pathway, has been implicated as being important for colonization of the streptomycin-treated mouse large intestine by Escherichia coli MG1655, a human commensal strain. In the present study, we report that an MG1655 Δedd mutant defective in the ED pathway grows poorly not only on gluconate as a sole carbon source but on a number of other sugars previously implicated as being important for colonization, including l-fucose, d-gluconate, d-glucuronate, N-acetyl-d-glucosamine, d-mannose, and d-ribose. Furthermore, we show that the mouse intestine selects mutants of MG1655 Δedd and wild-type MG1655 that have improved mouse intestine-colonizing ability and grow 15 to 30% faster on the aforementioned sugars. The mutants of MG1655 Δedd and wild-type MG1655 selected by the intestine are shown to be nonmotile and to have deletions in the flhDC operon, which encodes the master regulator of flagellar biosynthesis. Finally, we show that ΔflhDC mutants of wild-type MG1655 and MG1655 Δedd constructed in the laboratory act identically to those selected by the intestine; i.e., they grow better than their respective parents on sugars as sole carbon sources and are better colonizers of the mouse intestine

Integrated motivational interviewing and cognitive behavioural therapy for people with psychosis and comorbid substance misuse: randomised controlled trial

Objectives To evaluate the effectiveness of integrated motivational interviewing and cognitive behaviour therapy in addition to standard care for patients with psychosis and a co-morbid substance use problem. Design Two-centre, open, rater-blind randomised controlled trial Setting UK Secondary Care Participants 327 patients with clinical diagnoses of schizophrenia, schizophreniform or schizoaffective disorder and DSM-IV diagnoses of drug and/or alcohol dependence or abuse Interventions Participants were randomly allocated to integrated motivational interviewing and cognitive behaviour therapy or standard care. Therapy has two phases. Phase one – “motivation building” – concerns engaging the patient, then exploring and resolving ambivalence for change in substance use. Phase two –“Action” – supports and facilitates change using cognitive behavioural approaches. Up to 26 therapy sessions were delivered over one year. Main outcomes The primary outcome was death from any cause or admission to hospital in the 12 months after therapy. Secondary outcomes were frequency and amount of substance use (Timeline Followback), readiness to change, perceived negative consequences of use, psychotic symptom ratings, number and duration of relapses, global assessment of functioning and deliberate self harm, at 12 and 24 months, with additional Timeline Followback assessments at 6 and 18 months. Analysis was by intention-to-treat with robust treatment effect estimates. Results 327 participants were randomised. 326 (99.7%) were assessed on the primary outcome, 246 (75.2%) on main secondary outcomes at 24 months. Regarding the primary outcome, there was no beneficial treatment effect on hospital admissions/ death during follow-up, with 20.2% (33/163) of controls and 23.3% (38/163) of the therapy group deceased or admitted (adjusted odds-ratio 1.16; P= 0.579; 95% confidence interval 0.68 to 1.99). For secondary outcomes there was no treatment effect on frequency of substance use or perceived negative consequences, but a statistically significant effect of therapy on amount used per substance-using day (adjusted odds-ratios: (a) for main substance 1.50; P=0.016; 1.08 to 2.09, (b) all substances 1.48; P=0.017; 1.07 to 2.05). There was a statistically significant treatment effect on readiness to change use at 12 months (adjusted odds-ratio 2.05; P=0.004; 1.26 to 3.31), not maintained at 24 months. There were no treatment effects on assessed clinical outcomes. Conclusions Integrated motivational interviewing and cognitive behaviour therapy for people with psychosis and substance misuse does not improve outcome in terms of hospitalisation, symptom outcomes or functioning. It does result in a reduction in amount of substance use which is maintained over the year’s follow up. Trial registration Current Controlled Trials: ISRCTN1440448

Comment on “Search for Explanation of the Neutron Lifetime Anomaly”

We respond to issues raised by Serebrov et al. in a recent paper regarding systematic effects in the beam neutron lifetime experiment performed at NIST. We show that these effects were considered in the original analyses and that our corrections and systematic uncertainties were appropriate. We point out some misunderstandings in the analysis of Serebrov et al. None of the issues raised lead us to alter the value of the neutron lifetime reported

Comments on Systematic Effects in the NIST Beam Neutron Lifetime Experiment

We discuss issues raised by Serebrov, et al. in a recent paper regarding systematic effects in the beam neutron lifetime experiment performed at NIST. We show that these effects were considered in the original analyses and that our corrections and systematic uncertainties were appropriate. We point out some misconceptions and erroneous assumptions in the analysis of Serebrov, et al. None of the issues raised in Serebrov, et al lead us to alter the value of the neutron lifetime reported previously.Comment: arXiv admin note: substantial text overlap with arXiv:nucl-ex/0411041, arXiv:2004.0116

British Lung Foundation/United Kingdom primary immunodeficiency network consensus statement on the definition, diagnosis, and management of granulomatous-lymphocytic interstitial lung disease in common variable immunodeficiency disorders

A proportion of people living with common variable immunodeficiency disorders develop granulomatous-lymphocytic interstitial lung disease (GLILD). We aimed to develop a consensus statement on the definition, diagnosis, and management of GLILD. All UK specialist centers were contacted and relevant physicians were invited to take part in a 3-round online Delphi process. Responses were graded as Strongly Agree, Tend to Agree, Neither Agree nor Disagree, Tend to Disagree, and Strongly Disagree, scored +1, +0.5, 0, −0.5, and −1, respectively. Agreement was defined as greater than or equal to 80% consensus. Scores are reported as mean ± SD. There was 100% agreement (score, 0.92 ± 0.19) for the following definition: “GLILD is a distinct clinico-radio-pathological ILD occurring in patients with [common variable immunodeficiency disorders], associated with a lymphocytic infiltrate and/or granuloma in the lung, and in whom other conditions have been considered and where possible excluded.” There was consensus that the workup of suspected GLILD requires chest computed tomography (CT) (0.98 ± 0.01), lung function tests (eg, gas transfer, 0.94 ± 0.17), bronchoscopy to exclude infection (0.63 ± 0.50), and lung biopsy (0.58 ± 0.40). There was no consensus on whether expectant management following optimization of immunoglobulin therapy was acceptable: 67% agreed, 25% disagreed, score 0.38 ± 0.59; 90% agreed that when treatment was required, first-line treatment should be with corticosteroids alone (score, 0.55 ± 0.51)

The Two-Nucleon Potential from Chiral Lagrangians

Chiral symmetry is consistently implemented in the two-nucleon problem at low-energy through the general effective chiral lagrangian. The potential is obtained up to a certain order in chiral perturbation theory both in momentum and coordinate space. Results of a fit to scattering phase shifts and bound state data are presented, where satisfactory agreement is found for laboratory energies up to about 100 Mev.Comment: Postscript file; figures available by reques