Science of intracrinology in postmenopausal women

Univ Fed Sao Paulo, Dept Psicobiol, Sao Paulo, BrazilCasa Saude Santa Marcelina, Sao Paulo, SP, BrazilUniv Fed Sao Paulo, Dept Ginecol, Sao Paulo, BrazilUniv Fed Sao Paulo, Dept Psicobiol, Sao Paulo, BrazilUniv Fed Sao Paulo, Dept Ginecol, Sao Paulo, BrazilWeb of Scienc

Lack of sleep can jeopardize vaccine effectiveness

Univ Fed Sao Paulo, Dept Psychobiol, Sao Paulo, SP, BrazilUniv Fed Sao Paulo, Dept Gynecol, Sao Paulo, SP, BrazilDepartment of Psychobiology, Universidade Federal de São Paulo, São Paulo, SP, BrazilDepartment of Gynecology, Universidade Federal de São Paulo, São Paulo, SP, BrazilWeb of ScienceAssociação Fundo de Incentivo à Psicofarmacologia (AFIP)Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq

The distance Roman domination numbers of graphs

Hormone decline is common to all women during aging and, associated with other factors, leads to cognitive impairment. Its replacement enhances cognitive performance, but not all women present a clinical and family or personal history that justifies its use, mainly women with a history of cancer. The aim of this study was to determine whether a daily oral dose of 80 mg of isoflavone extract for 4 months can produce benefits in women with low hormone levels, contributing to improvement in cognitive aspects. The sample comprised 50- to 65-year-old women whose menstruation had ceased at least 1 year before and who had not undergone hormone replacement. The volunteers were allocated to two groups of 19 individuals each, i.e., isoflavone and placebo. There was a weak correlation between menopause duration and low performance in the capacity to manipulate information (central executive). We observed an increase in the capacity to integrate information in the group treated with isoflavone, but no improvement in the capacity to form new memories. We did not observe differences between groups in terms of signs and symptoms suggestive of depression according to the Geriatric Depression Scale. Our results point to a possible beneficial effect of isoflavone on some abilities of the central executive. These effects could also contribute to minimizing the impact of memory impairment. Further research based on controlled clinical trials is necessary to reach consistent conclusions

DIFFERENT ANTHROPOMETRIC MEASURES SHOULD BE USED TO EVALUATE OBSTRUCTIVE SLEEP APNEA IN THE WOMAN'S REPRODUCTIVE LIFE STAGES

Univ Fed Sao Paulo, Sao Paulo, BrazilUniv Fed Sao Paulo, Sao Paulo, BrazilWeb of ScienceAFIPCNPqFAPES

Is mindfulness associated with insomnia after menopause?

Objective Mindfulness has been defined as being intentionally aware of internal and external experiences that occur at the present moment, without judgment. Techniques that develop mindfulness, such as meditation, have positive effects on reducing insomnia, a sleep disorder that is common both during and after menopause. Our aim was to establish whether postmenopausal women with insomnia are less mindful than postmenopausal women without sleep disorders.Methods Postmenopausal women aged 50 to 65 years who did not use hormone therapy were recruited for the study. the sample included 14 women with insomnia and 12 women without insomnia or any other sleep disorder. the groups were comparable in age, schooling, and anxiety level. To assess mindfulness, we used the validated Mindful Attention Awareness Scale and the attentiveness domain of the Positive and Negative Affect ScheduleExpanded Form.Results Participants with insomnia were less mindful than healthy women. the level of mindfulness was able to discriminate the group with insomnia from the healthy group, with 71.4% accuracy.Conclusions Postmenopausal women with insomnia are less mindful than women without insomnia. Mindfulness-based interventions, such as meditation, may be beneficial for postmenopausal insomnia.Universidade Federal de São Paulo, Dept Psychobiol, São Paulo, BrazilUniversidade Federal de São Paulo, São Paulo, BrazilCasa Saude Santa Marcelina, São Paulo, BrazilHosp Israelita Albert Einstein, Inst Cerebro, São Paulo, BrazilUniversidade Federal de São Paulo, Dept Physiol, São Paulo, BrazilUniversidade Federal de São Paulo, Dept Psychobiol, São Paulo, BrazilUniversidade Federal de São Paulo, São Paulo, BrazilUniversidade Federal de São Paulo, Dept Physiol, São Paulo, BrazilWeb of ScienceAssociacao Fundo de Incentivo a PesquisaCoodenacao de Aperfeicoamento de Pessoal de Nivel SuperiorConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq

Estrogen therapy reduces nocturnal periodic limb movements

It is believed that periodic lirnb movement (PLM) and more specifically, restless leg syndrome (RLS), are a common cause of insomnia. and one study in the literature examined PLM when associated to the use of estrogens. Polo-Kantola et al. [Polo-Kantola P, Rauhala E, Erkkola R, Irjala K, Polo O. Estrogen replacement therapy and nocturnal periodic limb movements: a randomized controlled trial. Obstet Gynecol 2001;97(4):548-54] observed that estrogen therapy improved subjective sleep quality regardless of periodic limb movements or related arousals. Herein is a case of a symptomatic postmenopausal patient with high PLM index who complained of insomnia and leg pain. Given that the patient had hot flashes and a high Kupperman Menopausal Index (which evaluates climacteric symptoms), we decided to administer transdermal ESTRADOT 25 mu g (Novartis, Brazil) twice-a-week. Our patient experienced a significant decrease in PLM as well as a great increase in REM and a slight increase in slow wave sleep (stages 3 and 4), as shown in the polysomnography. the patient reported an overall improvement in her condition. (C) 2007 Elsevier Ireland Ltd. All rights reserved.Universidade Federal de São Paulo, Dept Med & Sleep Biol, São Paulo, BrazilUniversidade Federal de São Paulo, Dept Gynecol, São Paulo, BrazilUniversidade Federal de São Paulo, Dept Med & Sleep Biol, São Paulo, BrazilUniversidade Federal de São Paulo, Dept Gynecol, São Paulo, BrazilWeb of Scienc

Women’s Sleep Disorders: Integrative Care

The integrative care model is rooted in a biopsychosocial approach. Integrative is a term which refers to increasing the harmony and coherence of your whole being, and integrative care is therefore focused on the person, not on either the disease or a therapy. It is provided collaboratively by a health team comprising physicians, psychologists, physiotherapists, acupuncturists, and meditation, nutrition, and floral therapy. Previous studies have demonstrated that interventions based on the integrative care model improved womens lifestyle and quality of life. Our aim was to describe the use of complementary and alternative medicine (CAM) alongside traditional medicine among women with sleep conditions in our Womens Sleep Disorders Integrative Treatment Outpatient Clinic. We are sharing our experiences and clinical practice as the model we developed seems to have both physical and psychological benefits for women with sleep problems. We discuss the wide range of benefits that result from this type of complex intervention, and the contextual factors that may influence these benefits. This will inform future practitioners and we hope to contribute to quantitative research in the clinical setting The study highlights the importance of treating sleep complaints with a caring relationship and a CAM approach, alongside conventional medicine. Exploration of the lived experience of CAM and its meaning enables healthcare professionals to gain insights into the patients needs, preferences, and values. Gynecologists, clinicians, and health care providers should support and guide patients in their decision to use CAM by providing evidence-based and comprehensive advice on the potential benefits, risks and related safety issues of this approach.Univ Fed Sao Paulo, Dept Psychobiol, Sao Paulo, SP, BrazilUniv Fed Sao Paulo, Dept Gynecol, Sao Paulo, SP, BrazilUniv Fed Sao Paulo, Dept Nutr, Sao Paulo, SP, BrazilUniv Fed Sao Paulo, Dept Psychobiol, Sao Paulo, SP, BrazilUniv Fed Sao Paulo, Dept Gynecol, Sao Paulo, SP, BrazilUniv Fed Sao Paulo, Dept Nutr, Sao Paulo, SP, BrazilWeb of Scienc