5 research outputs found

    Phytochemical analysis and antimicrobial screening of crude extracts from the leaves, stem bark and root bark of Ekebergia senegalensis A. Juss

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    The leaves, stem bark and root bark of Ekebergia senegalensis, which has some traditional medicinal applications were investigated. Phytochemical analysis gave positive results for carbohydrates, glycosides, saponins, tannins and alkaloids. The crude methanol extracts showed growth inhibitory effects on Salmonella typhi, Pseudomonas, Klebsiella, Bacillus subtilis, Escherichia coli and Staphylococcus aureus. The minimum inhibitory concentration (MIC) of these extracts on the bacteriais 0.125 x 103 mg/ml for the methanol extracts. The minimum bactericidal concentration (MBC) determination showed that a concentration of 0.03125 x 103 mg/ml of the methanol extract of the leaves could completely kill S. typhi. The petroleum spirit extract did not show marked antimicrobial activity

    Phytochemical and antimicrobial studies on the leaves and stem ofDesmodium scorpiurus Der (sw)

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    Phytochemical studies on the aerial parts of Desmodium scorpiurus Der (sw) revealed the presence of alkaloids, saponins, glycosides, steroids and carbohydrates. The petroleum spirit, chloroform and methanol extracts were screened for antimicrobial activity using clinical isolates of Escherichia coli, Staphylococcus aureus, Salmonella typhi, Bacillus cereus, Streptococcus pyrogenes and Klebsiella pneumoniae. The results showed that the plant is very active against Pseudomonas aeruginosa,Escherichia coli and Streptococcus pyrogenes with minimum inhibitory concentration (MIC) of 2 x 102 mg/ml

    Phytochemical and antimicrobial screening of the crude petroleum spirit and methanol extracts of the stem bark, leaves and roots of Ficus thoningii (blume)

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    Ficus thoningii which has some traditional medicinal uses was investigated. Phytochemical screening of the stem bark, leaves and roots gave positive results for carbohydrates, glycosides, saponins and alkaloids. Antimicrobial screening of the crude petroleum spirit and methanol extracts showed activity against Klebsiella pneumoniae, Staphylococcus aureus, Escherichia coli, Providencia stauti and Bacillus subtilis but no activity was observed against Salmonella typhi. The crude petroleum spiritextracts of the leaves and stem bark of the plant had minimum inhibitory concentrations at 50 mg/ml while the roots had no minimum inhibitory concentration at the test concentration. The crude methanolextracts of the various plant parts showed minimum inhibitory concentration at 50 mg/ml on all the pathogens tested for

    Phytochemical Screening and Antimicrobial Analysis of Fadogia andersonii Robyn Plant Extract

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    Medicinal plants extracts are now generally considered as effective medicines that play a major role in modern pharmacy. The plant Fadogia andersonii belonging to the Family Rubiaceae, which is used in ethno-medicine was studied. Preliminary phytochemical analyses of the whole plant revealed the presence of the following metabolites: Saponins, terpenes, steroids, flavonoids, tannins, alkaloids, cardiac glycosides and carbohydrates. Anthraquinones was found to be absent. Antimicrobial screening of the methanol plant\u2019s extract carried out (in vitro) on Staphylococcus aureus , Escherichia coli , Salmonella typhi , Pseudomonas aeruginosa , Bacillus cereus , Klebsiella pneumonia, Streptococcus pneumoniae , Streptococcus pyogenes , Candida albican and Aspergillus flavus showed that the extract has activity on the tested microorganisms. However, it showed no inhibitory effect against Escherichia coli. The extract was found to inhibit the growth of S. aureus, B. cereus, S. pyogenes and C. albican at 25mg/ml with a corresponding MBC at 50mg/ml. S. typhi and S. pneumonia were inhibited at 50mg/ml with a corresponding MBC at 100mg/ml. It also inhibited the growth of P. aeruginosa, K. pneumonia and A. flavus at 100mg/ml with a corresponding MBC at 200mg/ml. The observed antimicrobial effects were believed to be due to the presence of active principles which were detected in the phytochemical screening
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