2,128 research outputs found

    Compression of the Duodenum by the Root of the Mesentery

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    Compression of the duodenum by the root of the mesentery is a rare pathological entity that has caused much controversy because it has been mistakenly identified as the superior mesenteric artery syndrome or the vascular compression of the duodenum. We discuss the pathological anatomy and the diagnosis of the disease, and report an illustrative case. Some authors report many cases of the syndrome, while others doubt its existence. Before surgery is considered, the diagnosis should be established beyond doubt and a prolonged period of observation, medical treatment, and nutritional support should be provided. The barium contrast swallowing test combined with aortographic studies can pinpoint the compression site behind the root of the mesentery. Good surgical results have been reported with both dextroposition of the duodenojejunal junction and with duodenojejunostomy

    Performance of Spatial Modulation using Measured Real-World Channels

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    In this paper, for the first time real-world channel measurements are used to analyse the performance of spatial modulation (SM), where a full analysis of the average bit error rate performance (ABER) of SM using measured urban correlated and uncorrelated Rayleigh fading channels is provided. The channel measurements are taken from an outdoor urban multiple input multiple output (MIMO) measurement campaign. Moreover, ABER performance results using simulated Rayleigh fading channels are provided and compared with a derived analytical bound for the ABER of SM, and the ABER results for SM using the measured urban channels. The ABER results using the measured urban channels validate the derived analytical bound and the ABER results using the simulated channels. Finally, the ABER of SM is compared with the performance of spatial multiplexing (SMX) using the measured urban channels for small and large scale MIMO. It is shown that SM offers nearly the same or a slightly better performance than SMX for small scale MIMO. However, SM offers large reduction in ABER for large scale MIMO.Comment: IEEE Vehicular Technology Conference Fall 2013 (VTC-Fall 2013), Accepte

    Terra sigillata in southern Latium:The evidence from the Pontine Region Project (1987-2014)

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    This contribution is the first of a series of publications by the authors to systematically disclose the wealth of material evidence collected during some 30 years of fieldwork in the Pontine region by the Pontine Region Project. This project has, since its inception in the mid-1980s, investigated more than 36 km2 of terrain across all major geomorphological units of the region, largely by means of systematic surface investigations. During these investigations, close to 200 000 artefacts were collected for further study, including c. 1 660 fragments of (Italian) terra sigillata, the emblematic, shiny red fine table ware of the Early Imperial period. In this article, we present a detailed spatial and contextual analysis of the terra sigillata fragments that have been gathered within the Pontine Region Project and discuss the results in light of economic issues (market integration, economic growth). We then supplement this evidence by published evidence of name stamps from surrounding areas to further expose to what extent, and in what ways, the different parts of southern Latium were embedded in the long-distance economic networks of the period

    BOSS-LDG: A Novel Computational Framework that Brings Together Blue Waters, Open Science Grid, Shifter and the LIGO Data Grid to Accelerate Gravitational Wave Discovery

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    We present a novel computational framework that connects Blue Waters, the NSF-supported, leadership-class supercomputer operated by NCSA, to the Laser Interferometer Gravitational-Wave Observatory (LIGO) Data Grid via Open Science Grid technology. To enable this computational infrastructure, we configured, for the first time, a LIGO Data Grid Tier-1 Center that can submit heterogeneous LIGO workflows using Open Science Grid facilities. In order to enable a seamless connection between the LIGO Data Grid and Blue Waters via Open Science Grid, we utilize Shifter to containerize LIGO's workflow software. This work represents the first time Open Science Grid, Shifter, and Blue Waters are unified to tackle a scientific problem and, in particular, it is the first time a framework of this nature is used in the context of large scale gravitational wave data analysis. This new framework has been used in the last several weeks of LIGO's second discovery campaign to run the most computationally demanding gravitational wave search workflows on Blue Waters, and accelerate discovery in the emergent field of gravitational wave astrophysics. We discuss the implications of this novel framework for a wider ecosystem of Higher Performance Computing users.Comment: 10 pages, 10 figures. Accepted as a Full Research Paper to the 13th IEEE International Conference on eScienc

    The Kepler Pixel Response Function

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    Kepler seeks to detect sequences of transits of Earth-size exoplanets orbiting Solar-like stars. Such transit signals are on the order of 100 ppm. The high photometric precision demanded by Kepler requires detailed knowledge of how the Kepler pixels respond to starlight during a nominal observation. This information is provided by the Kepler pixel response function (PRF), defined as the composite of Kepler's optical point spread function, integrated spacecraft pointing jitter during a nominal cadence and other systematic effects. To provide sub-pixel resolution, the PRF is represented as a piecewise-continuous polynomial on a sub-pixel mesh. This continuous representation allows the prediction of a star's flux value on any pixel given the star's pixel position. The advantages and difficulties of this polynomial representation are discussed, including characterization of spatial variation in the PRF and the smoothing of discontinuities between sub-pixel polynomial patches. On-orbit super-resolution measurements of the PRF across the Kepler field of view are described. Two uses of the PRF are presented: the selection of pixels for each star that maximizes the photometric signal to noise ratio for that star, and PRF-fitted centroids which provide robust and accurate stellar positions on the CCD, primarily used for attitude and plate scale tracking. Good knowledge of the PRF has been a critical component for the successful collection of high-precision photometry by Kepler.Comment: 10 pages, 5 figures, accepted by ApJ Letters. Version accepted for publication

    Mesothelioma mortality in Europe: impact of asbestos consumption and simian virus 40

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    BACKGROUND: It is well established that asbestos is the most important cause of mesothelioma. The role of simian virus 40 (SV40) in mesothelioma development, on the other hand, remains controversial. This potential human oncogene has been introduced into various populations through contaminated polio vaccines. The aim of this study was to investigate whether the possible presence of SV40 in various European countries, as indicated either by molecular genetic evidence or previous exposure to SV40-contaminated vaccines, had any effect on pleural cancer rates in the respective countries. METHODS: We conducted a Medline search that covered the period from January 1969 to August 2005 for reports on the detection of SV40 DNA in human tissue samples. In addition, we collected all available information about the types of polio vaccines that had been used in these European countries and their SV40 contamination status. RESULTS: Our ecological analysis confirms that pleural cancer mortality in males, but not in females, correlates with the extent of asbestos exposure 25 – 30 years earlier. In contrast, neither the presence of SV40 DNA in tumor samples nor a previous vaccination exposure had any detectable influence on the cancer mortality rate in neither in males (asbestos-corrected rates) nor in females. CONCLUSION: Using the currently existing data on SV40 prevalence, no association between SV40 prevalence and asbestos-corrected male pleural cancer can be demonstrated

    Conservation of grassland birds in North America: understanding ecological processes in different regions

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    Many species of birds that depend on grassland or savanna habitats have shown substantial overall population declines in North America. To understand the causes of these declines, we examined the habitat requirements of birds in six types of grassland in different regions of the continent. Open habitats were originally maintained by ecological drivers (continual and pervasive ecological processes) such as drought, grazing, and fire in tallgrass prairie, mixed-grass prairie, shortgrass prairie, desert grassland, and longleaf pine savanna. By contrast, grasslands were created by occasional disturbances (e.g., fires or beaver [Castor canadensis] activity) in much of northeastern North America. The relative importance of particular drivers or disturbances differed among regions. Keystone mammal species grazers such as prairie-dogs (Cynomys spp.) and bison (Bison bison) in western prairies, and dam-building beavers in eastern regions of the continent. Deciduous forests played a crucial, and frequently unappreciated, role in maintaining many grassland systems. Although fire was important in preventing invasion of woody plants in the tallgrass and moist mixed prairies, grazing played a more important role in maintaining the typical grassland vegetation of shortgrass prairies and desert grasslands. Heavy grazing by prairiedogs or bison created a low \u27grazing lawn\u27 that is the preferred habitat for many grassland bird species that are restricted to the shortgrass prairie and desert grasslands. Ultimately, many species of grassland birds are vulnerable because people destroyed their breeding, migratory, and wintering habitat, either directly by converting it to farmland and building lots, or indirectly by modifying grazing patterns, suppressing fires, or interfering with other ecological processes that originally sustained open grassland. Understanding the ecological processes that originally maintained grassland systems is critically important for efforts to improve, restore, or create habitat for grassland birds and other grassland organisms. Consequently, preservation of large areas of natural or seminatural grassland, where these processes can be studied and core populations of grassland birds can flourish, should be a high priority. However, some grassland birds now primarily depend on artificial habitats that are managed to maximize production of livestock, timber, or other products. With a sound understanding of the habitat requirements of grassland birds and the processes that originally shaped their habitats, it should be possible to manage populations sustainably on \u27working land\u27 such as cattle ranches, farms, and pine plantations. Proper management of private land will be critical for preserving adequate breeding, migratory, and winter habitat for grassland and savanna species

    Early outcomes of percutaneous pulmonary valve implantation using the Edwards SAPIEN XT transcatheter heart valve system

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    BACKGROUND: Patients with congenital or acquired heart defects affecting the pulmonary valve and right ventricular outflow tract (RVOT) commonly require multiple surgical interventions, resulting in significant morbidity. A less invasive alternative is percutaneous pulmonary valve implantation (PPVI). Though studies have previously reported the safety and efficacy of the early generation transcatheter heart valves (THVs), data on more recent devices are severely lacking. METHODS AND RESULTS: We performed a multinational, multicentre, retrospective, observational registry analysis of patients who underwent PPVI using the Edwards SAPIEN XT THV. Of the 46 patients that were enrolled, the majority had tetralogy of Fallot as the underlying diagnosis (58.7%), and stentless xenograft as the most common RVOT anatomy (34.8%). Procedural success rate was high (93.5%), with a low frequency of periprocedural complications and adverse events (6.5% and 10.9%, respectively). At 30days post-procedure, NYHA class had improved significantly (90.6% were at NYHA I or II). The rate of moderate/severe pulmonary regurgitation had decreased from 76.1% at baseline to 5.0% at 30days, and the calculated peak systolic gradient had decreased from 45.2 (SD±21.3) mmHg to 16.4 (SD±8.0) mmHg, with these values remaining low up to 2years. CONCLUSIONS: The data suggest the efficacy and safety of the SAPIEN XT THV in PPVI in common anatomies in patients with conduits, as well as those with native pulmonary valves or transannular patches. Continued data collection is necessary to verify long-term findings
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