899 research outputs found
Risk factors, ageing and signal transduction:special reference to metals and inositol phospholipid metabolism
Fixed-Node Monte Carlo Calculations for the 1d Kondo Lattice Model
The effectiveness of the recently developed Fixed-Node Quantum Monte Carlo
method for lattice fermions, developed by van Leeuwen and co-workers, is tested
by applying it to the 1D Kondo lattice, an example of a one-dimensional model
with a sign problem. The principles of this method and its implementation for
the Kondo Lattice Model are discussed in detail. We compare the fixed-node
upper bound for the ground state energy at half filling with
exact-diagonalization results from the literature, and determine several spin
correlation functions. Our `best estimates' for the ground state correlation
functions do not depend sensitively on the input trial wave function of the
fixed-node projection, and are reasonably close to the exact values. We also
calculate the spin gap of the model with the Fixed-Node Monte Carlo method. For
this it is necessary to use a many-Slater-determinant trial state. The
lowest-energy spin excitation is a running spin soliton with wave number pi, in
agreement with earlier calculations.Comment: 19 pages, revtex, contribution to Festschrift for Hans van Leeuwe
Design and experimental validation of a compact collimated Knudsen source
In this paper we discuss the design and performance of a collimated Knudsen
source which has the benefit of a simple design over recirculating sources.
Measurements of the flux, transverse velocity distribution and brightness at
different temperatures were conducted to evaluate the performance. The scaling
of the flux and brightness with the source temperature follow the theoretical
predictions. The transverse velocity distribution in the transparent operation
regime also agrees with the simulated data. The source was found able to
produce a flux of s at a temperature of 433 K. Furthermore the
transverse reduced brightness of an ion beam with equal properties as the
atomic beam reads A/(m sr eV) which is sufficient for
our goal: the creation of an ultra-cold ion beam by ionization of a
laser-cooled and compressed atomic rubidium beam
Cavity-enhanced photoionization of an ultracold rubidium beam for application in focused ion beams
A two-step photoionization strategy of an ultracold rubidium beam for
application in a focused ion beam instrument is analyzed and implemented. In
this strategy the atomic beam is partly selected with an aperture after which
the transmitted atoms are ionized in the overlap of a tightly cylindrically
focused excitation laser beam and an ionization laser beam whose power is
enhanced in a build-up cavity. The advantage of this strategy, as compared to
without the use of a build-up cavity, is that higher ionization degrees can be
reached at higher currents. Optical Bloch equations including the
photoionization process are used to calculate what ionization degree and
ionization position distribution can be reached. Furthermore, the ionization
strategy is tested on an ultracold beam of Rb atoms. The beam current is
measured as a function of the excitation and ionization laser beam intensity
and the selection aperture size. Although details are different, the global
trends of the measurements agree well with the calculation. With a selection
aperture diameter of 52 m, a current of pA is
measured, which according to calculations is 63% of the current equivalent of
the transmitted atomic flux. Taking into account the ionization degree the ion
beam peak reduced brightness is estimated at A/(msreV).Comment: 13 pages, 9 figure
Methylation Status of Imprinted Genes and Repetitive Elements in Sperm DNA from Infertile Males
Stochastic, environmentally and/or genetically induced disturbances in the genome-wide epigenetic reprogramming processes during male germ-cell development may contribute to male infertility. To test this hypothesis, we have studied the methylation levels of 2 paternally (H19 and GTL2) and 5 maternally methylated (LIT1, MEST, NESPAS, PEG3, and SNRPN) imprinted genes, as well as of ALU and LINE1 repetitive elements in 141 sperm samples, which were used for assisted reproductive technologies (ART), including 106 couples with strictly male-factor or combined male and female infertility and 28 couples with strictly female-factor infertility. Aberrant methylation imprints showed a significant association with abnormal semen parameters, but did not seem to influence ART outcome. Repeat methylation also differed significantly between sperm samples from infertile and presumably fertile males. However, in contrast to imprinted genes, ALU methylation had a significant impact on pregnancy and live-birth rate in couples with male-factor or combined infertility. ALU methylation was significantly high-er in sperm samples leading to pregnancy and live-birth than in those that did not. Sperm samples leading to abortions showed significantly lower ALU methylation levels than those leading to the birth of a baby. Copyright (C) 2011 S. Karger AG, Base
Same stimulus, same temporal context, different percept? Individual differences in hysteresis and adaptation when perceiving multistable dot lattices
Same stimulus, same temporal context, different percept? Individual differences in hysteresis and adaptation when perceiving multistable dot lattices
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