Comparison of plasma exo-iohexol, endo-iohexol and creatinine clearances in cats with low, normal and high glomerular filtration rates

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Antibodies Against Melanin

This study reports on unsuccessful attempts to produce antibodies against melanoprotein in rabbits. Available evidence suggests antibodies against melanocytes in the aetiology of vitiligo, but there is no convincing evidence for antibodies against melanin per se. It is suggested that the demonstration of antibodif's against an immune serum, obtained from rabbits after injection of a melanoma homogenate (which contained cell debris), may be due to antibodies against unmelanized or incompletely melanized melanosomes.S. Air. Med. J., 47, 7 (1973)

A novel consistent quality driven for JEM based distributed video coding

© 2019 by the authors. Distributed video coding (DVC) is an attractive and promising solution for low complexity constrained video applications, such as wireless sensor networks or wireless surveillance systems. In DVC, visual quality consistency is one of the most important issues to evaluate the performance of a DVC codec. However, it is the fact that the quality of the decoded frames that is achieved in most recent DVC codecs is not consistent and it is varied with high quality fluctuation. In this paper, we propose a novel DVC solution named Joint exploration model based DVC (JEM-DVC) to solve the problem, which can provide not only higher performance as compared to the traditional DVC solutions, but also an effective scheme for the quality consistency control. We first employ several advanced techniques that are provided in the Joint exploration model (JEM) of the future video coding standard (FVC) in the proposed JEM-DVC solution to effectively improve the performance of JEM-DVC codec. Subsequently, for consistent quality control, we propose two novel methods, named key frame quantization (KF-Q) andWyner-Zip frame quantization (WZF-Q), which determine the optimal values of the quantization parameter (QP) and quantization matrix (QM) applied for the key and WZ frame coding, respectively. The optimal values of QP and QM are adaptively controlled and updated for every key and WZ frames to guarantee the consistent video quality for the proposed codec unlike the conventional approaches. Our proposed JEM-DVC is the first DVC codec in literature that employs the JEM coding technique, and then all of the results that are presented in this paper are new. The experimental results show that the proposed JEM-DVC significantly outperforms the relevant DVC benchmarks, notably the DISCOVER DVC and the recent H.265/HEVC based DVC, in terms of both Peak signal-to-noise ratio (PSNR) performance and consistent visual quality

Sexual and marital trajectories and HIV infection among ever-married women in rural Malawi.

OBJECTIVE: To explore how sexual and marital trajectories are associated with HIV infection among ever-married women in rural Malawi. METHODS: Retrospective survey data and HIV biomarker data for 926 ever-married women interviewed in the Malawi Diffusion and Ideational Change Project were used. The associations between HIV infection and four key life course transitions considered individually (age at sexual debut, premarital sexual activity, entry into marriage and marital disruption by divorce or death) were examined. These transitions were then sequenced to construct trajectories that represent the variety of patterns in the data. The association between different trajectories and HIV prevalence was examined, controlling for potentially confounding factors such as age and region. RESULTS: Although each life course transition taken in isolation may be associated with HIV infection, their combined effect appeared to be conditional on the sequence in which they occurred. Although early sexual debut, not marrying one's first sexual partner and having a disrupted marriage each increased the likelihood of HIV infection, their risk was not additive. Women who both delayed sexual debut and did not marry their first partner are, once married, more likely to experience marital disruption and to be HIV-positive. Women who marry their first partner but who have sex at a young age, however, are also at considerable risk. CONCLUSIONS: These findings identify the potential of a life course perspective for understanding why some women become infected with HIV and others do not, as well as the differentials in HIV prevalence that originate from the sequence of sexual and marital transitions in one's life. The analysis suggests, however, the need for further data collection to permit a better examination of the mechanisms that account for variations in life course trajectories and thus in lifetime probabilities of HIV infection

An analysis of the Research Fellowship Scheme of the Royal College of Surgeons of England.

BACKGROUND: The Research Fellowship Scheme of the Royal College of Surgeons of England commenced in 1993 with the aim of exposing selected surgical trainees to research techniques and methodology, with the hope of having an impact on surgical research and increasing the cadre of young surgeons who might decide to pursue an academic career in surgery. Over 11 million pounds sterling (approximately US 20 million dollars) has been invested in 264 fellowships. The College wished to evaluate the impact of the Scheme on the careers of research fellows, surgical research, and patient care. As the 10th anniversary of the Scheme approached. STUDY DESIGN: Two-hundred and sixty research fellows whose current addresses were available were sent a questionnaire. Two-hundred and thirty-eight (91.5%) responded. RESULTS: Three-quarters of the research fellows conducted laboratory-based research, with most of the remainder conducting patient-based clinical research. One-third of the fellows who have reached consultant status have an academic component to their post. The total number of publications based on fellowship projects was 531, with a median impact factor of 3.5. Almost all fellows had been awarded a higher degree or were working toward this. Half of the fellows received subsequent funding for research, mostly awarded by national or international funding bodies. CONCLUSIONS: The Research Fellowship Scheme of the Royal College of Surgeons of England has successfully supported many trainee surgeons in the initial phase of their research career. It has helped surgical research by increasing the pool of surgeons willing to embark on an academic career. Indirectly, patient care has benefited by promoting an evidence-based culture among young surgeons. Such schemes are relevant to surgical training programs elsewhere if more young surgeons are to be attracted into academic surgery

Joint exploration model based light field image coding: A comparative study

© 2017 IEEE. The recent light field imaging technology has been attracting a lot of interests due to its potential applications in a large number of areas including Virtual Reality, Augmented Reality (VR/AR), Teleconferencing, and E-learning. Light Field (LF) data is able to provide rich visual information such as scene rendering with changes in depth of field, viewpoint, and focal length. However, Light Field data usually associates to a critical problem - the massive data. Therefore, compressing LF data is one of the main challenges in LF research. In this context, we present in this paper a comparative study for compressing LF data with not only the widely used image/video coding standards, such as JPEG-2000, H.264/AVC, HEVC and Google/VP9 but also with the most recent image/video coding solution, the Joint Exploration Model. In addition, this paper also proposes a LF image coding flow, which can be used as a benchmark for future LF compression evaluation. Finally, the compression efficiency of these coding solutions is thoroughly compared throughout a rich set of test conditions

A Method to Improve the Early Stages of the Robotic Process Automation Lifecycle

The robotic automation of processes is of much interest to organizations. A common use case is to automate the repetitive manual tasks (or processes) that are currently done by back-office staff through some information system (IS). The lifecycle of any Robotic Process Automation (RPA) project starts with the analysis of the process to automate. This is a very time-consuming phase, which in practical settings often relies on the study of process documentation. Such documentation is typically incomplete or inaccurate, e.g., some documented cases never occur, occurring cases are not documented, or documented cases differ from reality. To deploy robots in a production environment that are designed on such a shaky basis entails a high risk. This paper describes and evaluates a new proposal for the early stages of an RPA project: the analysis of a process and its subsequent design. The idea is to leverage the knowledge of back-office staff, which starts by monitoring them in a non-invasive manner. This is done through a screen-mousekey- logger, i.e., a sequence of images, mouse actions, and key actions are stored along with their timestamps. The log which is obtained in this way is transformed into a UI log through image-analysis techniques (e.g., fingerprinting or OCR) and then transformed into a process model by the use of process discovery algorithms. We evaluated this method for two real-life, industrial cases. The evaluation shows clear and substantial benefits in terms of accuracy and speed. This paper presents the method, along with a number of limitations that need to be addressed such that it can be applied in wider contexts.Ministerio de Economía y Competitividad TIN2016-76956-C3-2-

Diskursiewe patrone in Brandwaterkom van Alexander Strachan

The recently published and prizewinning novel Brandwaterkom is vintage Strachan with an intricate structure, imbedded stories and a whole network of allusions. Typical of postmodernist writing, the relationship between fact and fiction, historiography and the novel is problematized. The primary narrator is a Hermes-figure who constantly reflects upon the narrative in metafictional fashion, questioning and even belittling his own omniscience and omnipotence as narrator. The main story centres on Fanie Vilonel, a traitor during the Boer War, and the motif of treachery is central in the story, discourse and narration