50 research outputs found
Current Methods for Hyperpolarized [1-13C]pyruvate MRI Human Studies
- Author
- Bankson James A
- Bernard Jenna ML
- Bok Robert A
- BĂžgh Nikolaj
- Chen Albert P.
- Cunningham Charles H
- Gordon Jeremy
- Group the HP 13C MRI Consensus
- Hövener Jan-Bernd
- Larson Peder EZ
- Laustsen Christoffer
- Mayer Dirk
- McLean Mary A
- Schilling Franz
- Slater James
- Vanderheyden Jean-Luc
- Vigneron Daniel B
- von Morze Cornelius
- Xu Duan
- Publication venue
- Publication date
- 07/09/2023
- Field of study
MRI with hyperpolarized (HP) 13C agents, also known as HP 13C MRI, can
measure processes such as localized metabolism that is altered in numerous
cancers, liver, heart, kidney diseases, and more. It has been translated into
human studies during the past 10 years, with recent rapid growth in studies
largely based on increasing availability of hyperpolarized agent preparation
methods suitable for use in humans. This paper aims to capture the current
successful practices for HP MRI human studies with [1-13C]pyruvate - by far the
most commonly used agent, which sits at a key metabolic junction in glycolysis.
The paper is divided into four major topic areas: (1) HP 13C-pyruvate
preparation, (2) MRI system setup and calibrations, (3) data acquisition and
image reconstruction, and (4) data analysis and quantification. In each area,
we identified the key components for a successful study, summarized both
published studies and current practices, and discuss evidence gaps, strengths,
and limitations. This paper is the output of the HP 13C MRI Consensus Group as
well as the ISMRM Hyperpolarized Media MR and Hyperpolarized Methods &
Equipment study groups. It further aims to provide a comprehensive reference
for future consensus building as the field continues to advance human studies
with this metabolic imaging modality
Indirect traumatic optic neuropathy
- Author
- A Kesler
- A Kretz
- A Sen
- A Thakar
- A Thale
- AC Bain
- AK Mahapatra
- AK Mahapatra
- AK Mahapatra
- AM Kumaran
- B Coudrillier
- C Mayama
- CE Gross
- CE King
- CP Cornelius
- DHMD Smith
- G Zhilin
- GF Yavas
- H Bhattacharjee
- H Huempfner-Hierl
- H Kyung
- HH Tsai
- HP Venable
- J Huang
- J Li
- J Wang
- JC Downs
- JD Lindsey
- JH Weishaupt
- JY Chien
- K Miyake
- K Namekata
- KM Galetta
- L Groef De
- L Zhang
- LA Levin
- LA Levin
- M Entezari
- M Jorissen
- MB Kashkouli
- MG Rajiniganth
- MR Razeghinejad
- MT Pardue
- N Segal
- P Causin
- P Edwards
- P Henrich-Noack
- P Yu Wai Man
- P Yu-Wai-Man
- R Bhardwaj
- RE Raftopoulos
- RL Ford
- RW Carlsen
- S Bailoor
- S Cirovic
- S Thanos
- S Xiong
- SJ Manfredi
- SK Law
- T Fujikado
- T Fujitani
- T Kurimoto
- T Miyahara
- T Rossi
- TA Sullivan
- TD Nguyen
- TG Obenchain
- TM Wohlrab
- V Lee
- V Purvin
- V Vigneswara
- W Shi
- W Song
- WC Gordon
- X Wang
- X Wang
- Y Koriyama
- Y Qin
- Y Tagami
- YQ Wang
- YS Chen
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
The disruption of proteostasis in neurodegenerative diseases
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- Publication venue
- 'American Institute of Mathematical Sciences (AIMS)'
- Publication date
- 01/01/2015
- Field of study
Cells count on surveillance systems to monitor and protect the cellular proteome which, besides being highly heterogeneous, is constantly being challenged by intrinsic and environmental factors. In this context, the proteostasis network (PN) is essential to achieve a stable and functional proteome. Disruption of the PN is associated with aging and can lead to and/or potentiate the occurrence of many neurodegenerative diseases (ND). This not only emphasizes the importance of the PN in health span and aging but also how its modulation can be a potential target for intervention and treatment of human diseases.info:eu-repo/semantics/publishedVersio
Sustainable development education, practice, and research: an indigenous model of sustainable development at the College of Menominee Nation, Keshena, WI, USA
- Author
- A Kuper
- A Wiek
- AD Cortese
- American College Personnel Association
- B Arthur
- B Ceuppens
- B Giddings
- BC Hosmer
- C Cornelius
- Christopher M. Caldwell
- CMN
- D McGregor
- D McGregor
- DD Johnston
- DJ Grignon
- DJ Grignon
- DRM Beck
- DRM Beck
- E Ostrom
- E Salmon
- ED Schoolman
- ES Cameron
- F Berkes
- GA Cajete
- GD Peterson
- GM Hodgson
- H YoungBear-Tibbetts
- HP Huntington
- J Corntassel
- J Dator
- J Elkington
- J Kauffman
- JA Dator
- JH Greenberg
- Katherine Hall
- KP Whyte
- M Amer
- M Asch
- M Asch
- M Barth
- M Pecore
- M Pelican
- M Tamura
- M Yarime
- Michael J. Dockry
- MR Dove
- NC Peroff
- P Boyer
- P Geschiere
- P Schwartz
- PF Barlett
- PJ Taylor
- PM Jostad
- Q Gausset
- R Kimmerer
- R Pierotti
- RW Kates
- SO Keitumetse
- T Bernard
- T Bernard
- TR Miller
- V Deloria Jr
- W Lopik Van
- W Lopik Van
- William Van Lopik
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
International Consensus Statement on Rhinology and Allergy: Rhinosinusitis
- Author
- Aanaes K
- Abadie WM
- Abi Najm S
- Abigail P
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- American Academy of Pediatrics Steering Committee on Quality Improvement and Management (AAP SCQIM)
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- Chandy Z
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- ChiesaâEstomba CM
- Chin D
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- Chiu A
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- ZielinskaâBlizniewska H
- Zou L
- Zuckerman JD
- Zurlo JJ
- Zuskin E
- Äulig J
- Publication venue
- 'Wiley'
- Publication date
- 01/01/2021
- Field of study
Background: The 5 years since the publication of the first International Consensus Statement on Allergy and Rhinology: Rhinosinusitis (ICARâRS) has witnessed foundational progress in our understanding and treatment of rhinologic disease. These advances are reflected within the more than 40 new topics covered within the ICARâRSâ2021 as well as updates to the original 140 topics. This executive summary consolidates the evidenceâbased findings of the document. Methods: ICARâRS presents over 180 topics in the forms of evidenceâbased reviews with recommendations (EBRRs), evidenceâbased reviews, and literature reviews. The highest grade structured recommendations of the EBRR sections are summarized in this executive summary. Results: ICARâRSâ2021 covers 22 topics regarding the medical management of RS, which are grade A/B and are presented in the executive summary. Additionally, 4 topics regarding the surgical management of RS are grade A/B and are presented in the executive summary. Finally, a comprehensive evidenceâbased management algorithm is provided. Conclusion: This ICARâRSâ2021 executive summary provides a compilation of the evidenceâbased recommendations for medical and surgical treatment of the most common forms of RS
Hans Peter Cornelius (1888â1950): a perfect mapping geologist and scientific explorer of the Alps
- Author
- A Tollmann
- E Clar
- E Haberfelner
- E Spengler
- F Rössli
- HP Cornelius
- HP Cornelius
- HP Cornelius
- HP Cornelius
- HP Cornelius
- HP Cornelius
- HP Cornelius
- HP Cornelius
- HP Cornelius
- HP Cornelius
- HP Cornelius
- HP Cornelius
- HP Cornelius
- HP Cornelius
- HP Cornelius
- HP Cornelius
- HP Cornelius
- HR von GĂ€rtner
- J Cadisch
- J Nievoll
- MR Handy
- MR Handy
- O KĂŒhn
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
BeitrÀge zur Kenntnis der Schichtfolge und Tektonik der Lienzer Dolomiten
- Author
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/1953
- Field of study
Sphinctozoa aus den Klobenwand-Kalken (Trias, MĂŒrztaler Kalkalpen)
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/1967
- Field of study
Verwitterung und Bodenbildung
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/1953
- Field of study
Robustness of statistical tests for multiplicative terms in the additive main effects and multiplicative interaction model for cultivar trials
- Author
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study