487 research outputs found

    Cytochalasin B: Effects on Cell Morphology, Cell Adhesion, and Mucopolysaccharide Synthesis

    Full text link

    Selective effects of phorbol 12-myristate 13-acetate on myofibrils and 10-nm filaments.

    Full text link

    On the informational content of wage offers

    Get PDF
    This article investigates signaling and screening roles of wage offers in a single-play matching model with two-sided unobservable characteristics. It generates the following predictions as matching equilibrium outcomes: (i) “good” jobs offer premia if “high-quality” worker population is large; (ii) “bad” jobs pay compensating differentials if the proportion of “good” jobs to “low-quality” workers is large; (iii) all firms may offer a pooling wage in markets dominated by “high-quality” workers and firms; or (iv) Gresham’s Law prevails: “good” types withdraw if “bad” types dominate the population. The screening/signaling motive thus has the potential of explaining a variety of wage patterns

    Synthesis of myosin heavy and light chains in muscle cultures.

    Full text link

    Background studies for the EDELWEISS dark matter experiment

    Full text link
    The EDELWEISS-II collaboration has completed a direct search for WIMP dark matter using cryogenic Ge detectors (400 g each) and 384 kg×\timesdays of effective exposure. A cross-section of 4.4×1084.4 \times 10^{-8} pb is excluded at 90% C.L. for a WIMP mass of 85 GeV. The next phase, EDELWEISS-III, aims to probe spin-independent WIMP-nucleon cross-sections down to a few ×109\times10^{-9} pb. We present here the study of gamma and neutron background coming from radioactive decays in the set-up and shielding materials. We have carried out Monte Carlo simulations for the completed EDELWEISS-II setup with GEANT4 and normalised the expected background rates to the measured radioactivity levels (or their upper limits) of all materials and components. The expected gamma-ray event rate in EDELWEISS-II at 20-200 keV agrees with the observed rate of 82 events/kg/day within the uncertainties in the measured concentrations. The calculated neutron rate from radioactivity of 1.0-3.1 events (90% C.L.) at 20-200 keV in the EDELWEISS-II data together with the expected upper limit on the misidentified gamma-ray events (0.9\le0.9), surface betas (0.3\le0.3), and muon-induced neutrons (0.7\le0.7), do not contradict 5 observed events in nuclear recoil band. We have then extended the simulation framework to the EDELWEISS-III configuration with 800 g crystals, better material purity and additional neutron shielding inside the cryostat. The gamma-ray and neutron backgrounds in 24 kg fiducial mass of EDELWEISS-III have been calculated as 14-44 events/kg/day and 0.7-1.4 events per year, respectively. The results of the background studies performed in the present work have helped to select better purity components and improve shielding in EDELWEISS-III to further reduce the expected rate of background events in the next phase of the experiment.Comment: 15 pages, 9 figures, to be published in Astroparticle Physic

    Axion searches with the EDELWEISS-II experiment

    Full text link
    We present new constraints on the couplings of axions and more generic axion-like particles using data from the EDELWEISS-II experiment. The EDELWEISS experiment, located at the Underground Laboratory of Modane, primarily aims at the direct detection of WIMPs using germanium bolometers. It is also sensitive to the low-energy electron recoils that would be induced by solar or dark matter axions. Using a total exposure of up to 448 kg.d, we searched for axion-induced electron recoils down to 2.5 keV within four scenarios involving different hypotheses on the origin and couplings of axions. We set a 95% CL limit on the coupling to photons gAγ<2.13×109g_{A\gamma}<2.13\times 10^{-9} GeV1^{-1} in a mass range not fully covered by axion helioscopes. We also constrain the coupling to electrons, gAe<2.56×1011g_{Ae} < 2.56\times 10^{-11}, similar to the more indirect solar neutrino bound. Finally we place a limit on gAe×gANeff<4.70×1017g_{Ae}\times g_{AN}^{\rm eff}<4.70 \times 10^{-17}, where gANeffg_{AN}^{\rm eff} is the effective axion-nucleon coupling for 57^{57}Fe. Combining these results we fully exclude the mass range 0.91eV<mA<800.91\,{\rm eV}<m_A<80 keV for DFSZ axions and 5.73eV<mA<405.73\,{\rm eV}<m_A<40 keV for KSVZ axions
    corecore