1,920 research outputs found
The onset of homologous chromosome pairing during Drosophila melanogaster embryogenesis.
We have determined the position within the nucleus of homologous sites of the histone gene cluster in Drosophila melanogaster using in situ hybridization and high-resolution, three-dimensional wide field fluorescence microscopy. A 4.8-kb biotinylated probe for the histone gene repeat, located approximately midway along the short arm of chromosome 2, was hybridized to whole-mount embryos in late syncytial and early cellular blastoderm stages. Our results show that the two homologous histone loci are distinct and separate through all stages of the cell cycle up to nuclear cycle 13. By dramatic contrast, the two homologous clusters were found to colocalize with high frequency during interphase of cycle 14. Concomitant with homolog pairing at cycle 14, both histone loci were also found to move from their position near the midline of the nucleus toward the apical side. This result suggests that coincident with the initiation of zygotic transcription, there is dramatic chromosome and nuclear reorganization between nuclear cycles 13 and 14
Quantized representation of some nonlinear integrable evolution equations on the soliton sector
The Hirota algorithm for solving several integrable nonlinear evolution
equations is suggestive of a simple quantized representation of these equations
and their soliton solutions over a Fock space of bosons or of fermions. The
classical nonlinear wave equation becomes a nonlinear equation for an operator.
The solution of this equation is constructed through the operator analog of the
Hirota transformation. The classical N-solitons solution is the expectation
value of the solution operator in an N-particle state in the Fock space.Comment: 12 page
Anomalous Angular Dependence of the Dynamic Structure Factor near Bragg Reflections: Graphite
The electron energy-loss function of graphite is studied for momentum
transfers q beyond the first Brillouin zone. We find that near Bragg
reflections the spectra can change drastically for very small variations in q.
The effect is investigated by means of first principle calculations in the
random phase approximation and confirmed by inelastic x-ray scattering
measurements of the dynamic structure factor S(q,\omega). We demonstrate that
this effect is governed by crystal local field effects and the stacking of
graphite. It is traced back to a strong coupling between excitations at small
and large momentum transfers
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