270 research outputs found
Consumer Preferences for Rice Quality Characteristics in Accra and the Effects of these Preferences on Price
Les préférences des consommateurs pour les qualités caractéristiques du riz à Accra ont des effets spécifiques sur le prix du riz. Des analyses statistiques de la rélation entre le revenu et l'éducation des consommateurs et la qualité du riz qu'ils préfèrent, révèlent une rélation signifiante entre le revenu et l'éducation sur la forme et l' arôme. Aussi, le goût, le prix du détail et l' absence de la matière étrangère sont les qualités caractéristiques que la majorité des consommateurs préfèrent. Au contraire, la publicité, le conditionnement, le pourcentage du riz cassé ne sont pas les facteurs qui déterminent le choix des consommateurs à Accra. Une modèle hédonique de l'estimation du prix révèle que lesconsommateurs du riz à Accra paient beaucoup pour le gout, l' arôme et la forme. Les consommateurs paient aussi quelques primes pour le pourcentage inférieur du riz cassé et la pénurie d'un type du riz au marché. N'importe quel programme de la selection du riz pour lesmarchés ghannéens doit insister sur l'inhérente qualité caractéristique préférée par les consommateurs c-à-d le gout, la capacité de gonflement, l'arôme, la durée de la préparation et la forme. Les procésseurs et les vendeurs doivent viser à la réduction de la casse du grain et le niveau de la matière étrangère dans le produit final. Les vulgarisateurs doivent incorporer la production du riz de la qualité dans leur messages aux paysans, processeurs et marchands.Consumer preferences for quality characteristics of rice in Accra have specific effects on the price of rice. Statistical analysis of the relationship between income and education of consumers and the quality of rice they prefer, reveal a significant relationship between income and education on shape and aroma. Also, taste, retail price and absence of foreign matter are the quality attributes that most consumers prefer. Low percentage broken, type of packaging and advertisement are the factors least cited by consumers as influencing their choice of rice in Accra. A hedonic price estimation model reveals that consumers of rice in Accra pay highest premiums for taste, aroma and shape. Consumers also pay some premium for smaller percentage broken and scarcity of a type of rice in the market. Any breeding programme for rice for Ghanaian markets should emphasize on the inherent quality characteristics consumers are sensitive to and these include taste, swelling capacity, aroma, cooking time, and shape. Processors and marketers should aim at reducing breakage of grain and levels of foreign matter in the final product. Extension systems should incorporate the production of quality rice in their messages to farmers, processors and traders
Influence of Fatty Acid Methyl Esters on Fuel properties of Biodiesel Produced from the Seeds Oil of Curcubita pepo
Oil extracted from the seeds of Curcubita pepo was transesterified using potassium hydroxide in methanol. Fatty acid methyl esters (FAME) profile of the produced diesel was analyzed using Gas chromatograph coupled with mass spectrophotometer (GC-MS). The results indicate the presence of methyl (12E)-octadecenotate as the dominant ester with approximate percentage by composition of 82.90%. Other esters detected were methyl tetradecanoate (0.4%), methyl eicosonoate (2.48%), methyl docosanoate (0.97%) methyl teracosanoate (0.47%). Some critical fuel parameters like oxidation stability, cetane number, iodine value and viscosity were correlated with the methyl ester composition and structural
configuration. It was found that the cetane number and oxidation stability of the produced biodiesel is a function of the degree of unsaturation and long chain saturated factor. The profile of methyl esters in the biodiesel produced indicates its likelihood to be a viable fuel source for internal combustion engines
Endovascular covered stenting for the management of post-percutaneous nephrolithotomy renal pseudoaneurysm: a case report
<p>Abstract</p> <p>Introduction</p> <p>Intrarenal pseudoaneurysm is a rare, yet clinically significant, complication of percutaneous nephrolithotomy. A high index of clinical suspicion is necessary in order to recognize pseudoaneurysm as the cause of delayed bleeding after percutaneous nephrolithotomy and angiography confirms the diagnosis which allows endovascular management.</p> <p>Case presentation</p> <p>We present a case of a 65-year old Caucasian woman who underwent percutaneous nephrolithotomy in the supine position for a two centimetre renal calculus. The postoperative course was complicated by persistent bleeding due to a renal pseudoaneurysm. The vascular lesion was successfully managed by endovascular exclusion through the use of a covered stent graft. We report the first successful use of this method for the management of iatrogenic pseudoaneurysm in a branch of the left renal artery and we focus on the imaging findings, technical details, advantages and limitations of this technique.</p> <p>Conclusion</p> <p>As a result of its high efficacy, interventional radiology has largely replaced open surgery for the management of renal pseudoaneurysm related to percutaneous nephrolithotomy. Recent technical advancements have allowed the use of covered stent grafts as an alternative to embolisation for the angiographic management of visceral artery pseudoaneurysm located in other organs. This novel technique allows the endovascular exclusion of the pseudoaneurysm, without compromising arterial supply to the end-structures - an advantage of critical importance in organs supplied by segmental arteries - in the absence of collateral vasculature, such as the kidney.</p
Differential postural effects of plantar-flexor muscles fatigue under normal, altered and improved vestibular and neck somatosensory conditions
The aim of the present study was to assess the effects of plantar-flexor
muscles fatigue on postural control during quiet standing under normal, altered
and improved vestibular and neck somatosensory conditions. To address this
objective, young male university students were asked to stand upright as still
as possible with their eyes closed in two conditions of No Fatigue and Fatigue
of the plantar-flexor muscles. In Experiment 1 (n=15), the postural task was
executed in two Neutral head and Head tilted backward postures, recognized to
degrade vestibular and neck somatosensory information. In Experiment 2 (n=15),
the postural task was executed in two conditions of No tactile and Tactile
stimulation of the neck provided by the application of strips of adhesive
bandage to the skin over and around the neck. Centre of foot pressure
displacements were recorded using a force platform. Results showed that (1) the
Fatigue condition yielded increased CoP displacements relative to the No
Fatigue condition (Experiment 1 and Experiment 2), (2) this destabilizing
effect was more accentuated in the Head tilted backward posture than Neutral
head posture (Experiment 1) and (3) this destabilizing effect was less
accentuated in the condition of Tactile stimulation than that of No tactile
stimulation of the neck (Experiment 2). In the context of the multisensory
control of balance, these results suggest an increased reliance on vestibular
and neck somatosensory information for controlling posture during quiet
standing in condition of altered ankle neuromuscular function
Caspase-dependent and -independent suppression of apoptosis by monoHER in Doxorubicin treated cells
Doxorubicin (DOX) is an antitumour agent for different types of cancer, but the dose-related cardiotoxicity limits its clinical use. To prevent this side effect we have developed the flavonoid monohydroxyethylrutoside (monoHER), a promising protective agent, which did not interfere with the antitumour activity of DOX. To obtain more insight in the mechanism underlying the selective protective effects of monoHER, we investigated whether monoHER (1 mM) affects DOX-induced apoptosis in neonatal rat cardiac myocytes (NeRCaMs), human endothelial cells (HUVECs) and the ovarian cancer cell lines A2780 and OVCAR-3. DOX-induced cell death was effectively reduced by monoHER in heart, endothelial and A2780 cells. OVCAR-3 cells were highly resistant to DOX-induced apoptosis. Experiments with the caspase-inhibitor zVAD-fmk showed that DOX-induced apoptosis was caspase-dependent in HUVECs and A2780 cells, whereas caspase-independent mechanisms seem to be important in NeRCaMs. MonoHER suppressed DOX-dependent activation of the mitochondrial apoptotic pathway in normal and A2780 cells as illustrated by p53 accumulation and activation of caspase-9 and -3 cleavage. Thus, monoHER acts by suppressing the activation of molecular mechanisms that mediate either caspase-dependent or -independent cell death. In light of the current work and our previous studies, the use of clinically achievable concentrations of monoHER has no influence on the antitumour activity of DOX whereas higher concentrations as used in the present study could influence the antitumour activity of DOX
Development and content validity of a patient reported outcomes measure to assess symptoms of major depressive disorder
<p>Abstract</p> <p>Background</p> <p>Although many symptoms of Major Depressive Disorder (MDD) are assessed through patient-report, there are currently no patient-reported outcome (PRO) instruments that incorporate documented evidence of patient input in PRO instrument development. A review of existing PROs used in MDD suggested the need to conduct qualitative research with patients with MDD to better understand their experience of MDD and develop an evaluative instrument with content validity. The aim of this study was to develop a disease-specific questionnaire to assess symptoms important and relevant to adult MDD patients.</p> <p>Methods</p> <p>The questionnaire development involved qualitative interviews for concept elicitation, instrument development, and cognitive interviews to support content validity. For concept elicitation, ten MDD severity-specific focus group interviews with thirty-eight patients having clinician-confirmed diagnoses of MDD were conducted in January 2009. A semi-structured discussion guide was used to elicit patients' spontaneous descriptions of MDD symptoms. Verbatim transcripts of focus groups were coded and analyzed to develop a conceptual framework to describe MDD. A PRO instrument was developed by operationalizing concepts elicited in the conceptual framework. Cognitive interviews were carried out in patients (n = 20) to refine and test the content validity of the instrument in terms of item relevance and comprehension, instructions, recall period, and response categories.</p> <p>Results</p> <p>Concept elicitation focus groups identified thirty-five unique concepts falling into several domains: i) emotional, ii) cognitive, iii) motivation, iv) work, v) sleep, vi) appetite, vii) social, viii) activities of daily living, ix) tired/fatigue, x) body pain, and xi) suicidality. Concept saturation, the point at which no new relevant information emerges in later interviews, was achieved for each of the concepts. Based on the qualitative findings, the PRO instrument developed had 15 daily and 20 weekly items. The cognitive interviews confirmed that the instructions, item content, and response scales were understood by the patients.</p> <p>Conclusions</p> <p>Rigorous qualitative research resulted in the development of a PRO measure for MDD with supported content validity. The MDD PRO can assist in understanding and assessing MDD symptoms from patients' perspectives as well as evaluating treatment benefit of new targeted therapies.</p
Molecular identification of adenovirus causing respiratory tract infection in pediatric patients at the University of Malaya Medical Center
<p>Abstract</p> <p>Background</p> <p>There are at least 51 adenovirus serotypes (AdV) known to cause human infections. The prevalence of the different human AdV (HAdV) serotypes varies among different regions. Presently, there are no reports of the prevalent HAdV types found in Malaysia. The present study was undertaken to identify the HAdV types associated primarily with respiratory tract infections (RTI) of young children in Malaysia.</p> <p>Methods</p> <p>Archived HAdV isolates from pediatric patients with RTI seen at the University of Malaya Medical Center (UMMC), Kuala Lumpur, Malaysia from 1999 to 2005 were used. Virus isolates were inoculated into cell culture and DNA was extracted when cells showed significant cytopathic effects. AdV partial hexon gene was amplified and the sequences together with other known HAdV hexon gene sequences were used to build phylogenetic trees. Identification of HAdV types found among young children in Malaysia was inferred from the phylograms.</p> <p>Results</p> <p>At least 2,583 pediatric patients with RTI sought consultation and treatment at the UMMC from 1999 to 2005. Among these patients, 48 (< 2%) were positive for HAdV infections. Twenty-seven isolates were recovered and used for the present study. Nineteen of the 27 (~70%) isolates belonged to HAdV species C (HAdV-C) and six (~22%) were of HAdV species B (HAdV-B). Among the HAdV-C species, 14 (~74%) of them were identified as HAdV type 1 (HAdV-1) and HAdV type 2 (HAdV-2), and among the HAdV-B species, HAdV type 3 (HAdV-3) was the most common serotype identified. HAdV-C species also was isolated from throat and rectal swabs of children with hand, foot, and mouth disease (HFMD). Two isolates were identified as corresponding to HAdV-F species from a child with HFMD and a patient with intestinal obstruction.</p> <p>Conclusions</p> <p>HAdV-1 and HAdV-2 were the most common HAdV isolated from pediatric patients who sought treatment for RTI at the UMMC from 1999 to 2005. HAdV-B, mainly HAdV-3, was recovered from ~22% of the patients. These findings provide a benchmark for future studies on the prevalence and epidemiology of HAdV types in Malaysia and in the region.</p
Влияние интенсивности механической активации на структуру гексагонального нитрида бора
Изучено влияние интенсивности механической активации на микроструктуру и свойства гексагонального нитрида бора (hBN).Вивчено вплив інтенсивності механічної активації на мікроструктуру і властивості гексагонального нітриду бору (hBN).The mechanical activation intensity effect on the microstructure and properties of hexagonal boron nitride (hBN) has been studied
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