Comparación in vitro de la acción fungicida de solución saturada de azúcar y nitrato de econazol

En investigaciones previas realizadas in vitro con solución saturada de sacarosa, eugenol y polietilenglicol 400 secomprobó su eficacia fungicida sobre Candida albicans.Se comparó en las mismas condiciones el efecto fungicida con nitrato de econazol. Una suspensión de Candidaalbicans con nitrato de econazol se repicó en Agar Sabouraud 20 a distintos tiempos para demostrar la viabilidadde la cepa.El tiempo promedio de muerte de Candida albicans en la solución saturada de sacarosa fue de 300 segundos, ennitrato de econazol fue de pocos segundos.Aunque existen diferencias significativas en el tiempo de muerte de la cepa ensayada, la solución saturada desacarosa sería una contribución terapéutica alternativa, en aquellos pacientes con lesiones cutáneas crónicas que noresponden a los tratamientos tradicionales

Comparison in vitro of saturated saccharose solution fungicide action against econazol nitrate

En investigaciones previas realizadas in vitro con solución saturada de sacarosa, eugenol y polietilenglicol 400 se comprobó su eficacia fungicida sobre Candida albicans. Se comparó en las mismas condiciones el efecto fungicida con nitrato de econazol. Una suspensión de Candida albicans con nitrato de econazol se repicó en Agar Sabouraud 20 a distintos tiempos para demostrar la viabilidad de la cepa. El tiempo promedio de muerte de Candida albicans en la solución saturada de sacarosa fue de 300 segundos, en nitrato de econazol fue de pocos segundos. Aunque existen diferencias significativas en el tiempo de muerte de la cepa ensayada, la solución saturada de sacarosa sería una contribución terapéutica alternativa, en aquellos pacientes con lesiones cutáneas crónicas que no responden a los tratamientos tradicionales.Previous research projects, carried out in vitro with saturated saccharose solution, checked eugenol and polyethylenglycol 400 for their effectiveness as a fungicide for Candida albicans. Under the same conditions the fungicidal effect of econazol nitrate was compared. A suspension of Candida Albicans, with econazol nitrate, was finely cut in sabouraud agar 20, over different time periods, in order to demonstrate the viability of the strain. The average time period in which the death of Candida albicans occurred in the saturated sucrose solution was 300 seconds, while in the case of econazol nitrate a few seconds. Although significant time differences exist in the death of the strain tested, the saturated sucrose solution could provide an alternative therapeutic contribution for those patients with chronic cutaneous lesions that do not respond to traditional treatments

Extension of the Combustion Stability Range in Dry Low NO x Lean Premixed Gas Turbine Combustor Using a Fuel Rich Annular Pilot Burner

The present work is concerned with improving combustion stability in lean premixed (LP) gas turbine combustors by injecting free radicals into the combustion zone. The work is a joint experimental and numerical effort aimed at investigating the feasibility of incorporating a circumferential pilot combustor, which operates under rich conditions and directs its radicals enriched exhaust gases into the main combustion zone as the means for stabilization. The investigation includes the development of a chemical reactors network (CRN) model that is based on perfectly stirred reactors modules and on preliminary CFD analysis as well as on testing the method on an experimental model under laboratory conditions. The study is based on the hypothesis that under lean combustion conditions, combustion instability is linked to local extinctions of the flame and consequently, there is a direct correlation between the limiting conditions affecting combustion instability and the lean blowout (LBO) limit of the flame. The experimental results demonstrated the potential reduction of the combustion chamber's LBO limit while maintaining overall NO x emission concentration values within the typical range of low NO x burners and its delicate dependence on the equivalence ratio of the ring pilot flame. A similar result was revealed through the developed CHEMKIN-PRO CRN model that was applied to find the LBO limits of the combined pilot burner and main combustor system, while monitoring the associated emissions. Hence, both the CRN model, and the experimental results, indicate that the radicals enriched ring jet is effective at stabilizing the LP flame, while keeping the NO x emission level within the characteristic range of low NO x combustors