Evolution of the Milky Way halo by accretion of dwarf satellite galaxies

Within the Cold Dark Matter scenario the hierarchical merging paradigm is the natural result to form massive galactic halos by the minor mergers of sub-halos and, by this, inherently their stellar halo. Although this must be also invoked for the Milky Way, the context of chemical and kinematic coherence of halo stars and dwarf spheroidal galaxies is yet unsolved a focus of present-day research. To examine this issue we model the chemo-dynamical evolution of the system of satellites selected from the cosmological Via Lactea II simulations to be similar for the Milky Way environment but at an early epoch.Comment: 3 pages, 2 figures, to appear in the proceedings of the CRAL conference, Lyon, June 2010, "A Universe of Dwarf Galaxies", eds. Philippe Prugniel & Mina Koleva; EDP Sciences in the European Astronomical Society Publications Serie

Bose-Einstein condensation of chromium

We report on the generation of a Bose-Einstein condensate in a gas of chromium atoms, which will make studies of the effects of anisotropic long-range interactions in degenerate quantum gases possible. The preparation of the chromium condensate requires novel cooling strategies that are adapted to its special electronic and magnetic properties. The final step to reach quantum degeneracy is forced evaporative cooling of 52Cr atoms within a crossed optical dipole trap. At a critical temperature of T~700nK, we observe Bose-Einstein condensation by the appearance of a two-component velocity distribution. Released from an anisotropic trap, the condensate expands with an inversion of the aspect ratio. We observe critical behavior of the condensate fraction as a function of temperature and more than 50,000 condensed 52Cr atoms.Comment: 4 pages, 4 figure

Damagnetization cooling of a gas

We demonstrate demagnetization cooling of a gas of ultracold $^{52}$Cr atoms. Demagnetization is driven by inelastic dipolar collisions which couple the motional degrees of freedom to the spin degree. By that kinetic energy is converted into magnetic work with a consequent temperature reduction of the gas. Optical pumping is used to magnetize the system and drive continuous demagnetization cooling. Applying this technique, we can increase the phase space density of our sample by one order of magnitude, with nearly no atom loss. This method can be in principle extended to every dipolar system and could be used to achieve quantum degeneracy via optical means.Comment: 10 pages, 5 figure

Carbohydrate Catabolism in Phaeobacter inhibens DSM 17395, a Member of the Marine Roseobacter Clade

Since genome analysis did not allow unambiguous reconstruction of transport, catabolism, and substrate-specific regulation for several important carbohydrates in Phaeobacter inhibens DSM 17395, proteomic and metabolomic analyses of N-acetylglucosamine-, mannitol-, sucrose-, glucose-, and xylose-grown cells were carried out to close this knowledge gap. These carbohydrates can pass through the outer membrane via porins identified in the outer membrane fraction. For transport across the cytoplasmic membrane, carbohydrate-specific ABC transport systems were identified. Their coding genes mostly colocalize with the respective "catabolic" and "regulatory" genes. The degradation of N-acetylglucosamine proceeds via N-acetylglucosamine-6-phosphate and glucosamine-6-phosphate directly to fructose-6-phosphate; two of the three enzymes involved were newly predicted and identified. Mannitol is catabolized via fructose, sucrose via fructose and glucose, glucose via glucose-6-phosphate, and xylose via xylulose-5-phosphate. Of the 30 proteins predicted to be involved in uptake, regulation, and degradation, 28 were identified by proteomics and 19 were assigned to their respective functions for the first time. The peripheral degradation pathways feed into the Entner-Doudoroff (ED) pathway, which is connected to the lower branch of the Embden-Meyerhof-Parnas (EMP) pathway. The enzyme constituents of these pathways displayed higher abundances in P. inhibens DSM 17395 cells grown with any of the five carbohydrates tested than in succinate-grown cells. Conversely, gluconeogenesis is turned on during succinate utilization. While tricarboxylic acid (TCA) cycle proteins remained mainly unchanged, the abundance profiles of their metabolites reflected the differing growth rates achieved with the different substrates tested. Homologs of the 74 genes involved in the reconstructed catabolic pathways and central metabolism are present in various Roseobacter clade members

On the stellar populations in NGC 185 and NGC 205, and the nuclear star cluster in NGC 205 from Hubble Space Telescope observations

[Abridged] We present a first detailed analysis of resolved stellar populations in the dwarf galaxies NGC 185 and NGC 205 based on archival V- and I-band WFPC2 pointings. For NGC 185 we deduce that star formation was probably still active about 4 x 10^8 yr ago. Key abundance-related results are: (1) We identify ancient stars with [Fe/H] <~ -1.5 dex by a well-defined horizontal branch (HB). (2) We find a prominent RGB/ faint-AGB clump/ bump- like feature with the same mean V-band magnitude as the HB, within uncertainties; from a comparison with theory, ancient stars have [Fe/H] ~ -1.5 dex, with a higher abundance level for intermediate-age stars. (3) From colour information we infer that the median [Fe/H] > -1.11 +/- 0.08 dex for ancient stars. For NGC 205, we record (m-M)o = 24.76 +/- 0.1 mag, based on the RGB I-band tip magnitude method. We find that stars were probably still forming less than 3 x 10^8 yr ago, which is compatible with star formation triggered by an interaction with M31. Key abundance-related results are: (1) The RGB/ faint-AGB is significantly skewed to redder values than that of a control field in the outskirts of M31; it probably results from a relatively narrow metallicity and or age range for a significant fraction of the dwarf's stars. (2) For ancient stars we infer from colour information that the median [Fe/H] > -1.06+/-0.04 dex. We briefly compare the stellar populations of NGC 205, NGC 185 and NGC 147. Finally, we find an apparent blue excess in the outer region of the nuclear star cluster in NGC 205. It is as compact as a typical galactic globular cluster, but is quite bright (10^6 L_solar,R); and by matching its blue colour with models, its stellar population is young, up to a few times 10^8 yr old.Comment: To appear in the May edition of the Astronomical Journal. Some figures have been degraded in quality for the purpose of submissio

BCS pairing in a trapped dipolar Fermi gase

We present a detailed study of the BCS pairing transition in a trapped polarized dipolar Fermi gas. In the case of a shallow nearly spherical trap, we find the decrease of the transition temperature as a function of the trap aspect ratio and predict the existence of the optimal trap geometry. The latter corresponds to the highest critical temperature of the BCS transition for a given number of particles. We also derive the phase diagram for an ultracold trapped dipolar Fermi gases in the situation, where the trap frequencies can be of the order of the critical temperature of the BCS transition in the homogeneous case, and find the critical value of the dipole-dipole interaction energy, below which the BCS transition ceases to exist. The critical dipole strength is obtained as a function of the trap aspect ratio. Alternatively, for a given dipole strength there is a critical value of the trap anisotropy for the BCS state to appear. The order parameter calculated at criticality, exhibits nover non-monotonic behavior resulted from the combined effect of the confining potential and anisotropic character of the interparticle dipole-dipole interation.Comment: 14 pages, 3 figure

Anthracimycin activity against contemporary methicillin-resistant Staphylococcus aureus.

Anthracimycin is a recently discovered novel marine-derived compound with activity against Bacillus anthracis. We tested anthracimycin against an expanded panel of Staphylococcus aureus strains in vitro and in vivo. All strains of S. aureus tested, including methicillin-susceptible, methicillin-resistant (MRSA) and vancomycin-resistant strains of S. aureus, were susceptible to anthracimycin at MIC values of ⩽0.25 mg l(-1). Although its postantibiotic effects were minimal, anthracimycin exhibited potent and rapid bactericidal activity, with a &gt;4-log kill of USA300 MRSA within 3 h at five times its MIC. At concentrations significantly below the MIC, anthracimycin slowed MRSA growth and potentiated the bactericidal activity of the human cathelicidin, LL-37. The bactericidal activity of anthracimycin was somewhat mitigated in the presence of 20% human serum, and the compound was minimally toxic to human cells, with an IC50 (inhibitory concentration 50)=70 mg l(-1) against human carcinoma cells. At concentrations near the MIC, anthracimycin inhibited S. aureus nucleic acid synthesis as determined by optimized macromolecular synthesis methodology, with inhibition of DNA and RNA synthesis occurring in the absence of DNA intercalation. Anthracimycin at a single dose of 1 or 10 mg kg(-1) was able to protect mice from MRSA-induced mortality in a murine peritonitis model of infection. Anthracimycin provides an interesting new scaffold for future development of a novel MRSA antibiotic

Production of a chromium Bose-Einstein condensate

The recent achievement of Bose-Einstein condensation of chromium atoms [1] has opened longed-for experimental access to a degenerate quantum gas with long-range and anisotropic interaction. Due to the large magnetic moment of chromium atoms of 6 {$\mu$}B, in contrast to other Bose- Einstein condensates (BECs), magnetic dipole-dipole interaction plays an important role in a chromium BEC. Many new physical properties of degenerate gases arising from these magnetic forces have been predicted in the past and can now be studied experimentally. Besides these phenomena, the large dipole moment leads to a breakdown of standard methods for the creation of a chromium BEC. Cooling and trapping methods had to be adapted to the special electronic structure of chromium to reach the regime of quantum degeneracy. Some of them apply generally to gases with large dipolar forces. We present here a detailed discussion of the experimental techniques which are used to create a chromium BEC and alow us to produce pure condensates with up to {$10^5$} atoms in an optical dipole trap. We also describe the methods used to determine the trapping parameters.Comment: 17 pages, 9 figure