Formation and Radiative Feedback of First Objects and First Galaxies

First, the formation of first objects driven by dark matter is revisited by high-resolution hydrodynamic simulations. It is revealed that dark matter haloes of ~10^4M_sun can produce first luminous objects with the aid of dark matter cusps. Therefore, the mass of first objects is smaller by roughly two orders of magnitude than in the previous prediction. This implies that the number of Pop III stars formed in the early universe could be significantly larger than hitherto thought. Secondly, the feedback by photo-ionization and photo-dissociation photons in the first objects is explored with radiation hydrodynamic simulations, and it is demonstrated that multiple stars can form in a 10^5M_sun halo. Thirdly, the fragmentation of an accretion disk around a primordial protostar is explored with photo-dissociation feedback. As a result, it is found that the photo-dissociation can reduce the mass accretion rate onto protostars. Also, protostars as small as 0.8M_sun may be ejected and evolve with keeping their mass, which might be detected as "real first stars" in the Galactic halo. Finally, state-of-the-art radiation hydrodynamic simulations are performed to investigate the internal ionization of first galaxies and the escape of ionizing photons. We find that UV feedback by forming massive stars enhances the escape fraction even in a halo as massive as > 6* 10^9M_sun, while it reduces the star formation rate significantly. This may have a momentous impact on the cosmic reionization.Comment: 26 pages, 14 figure

アトラクションとしての日常に関する実践メディア論的考察

学位の種別:論文博士University of Tokyo(東京大学

Characteristics of Advanced Colorectal Cancer Detected by Fecal Immunochemical Test Screening in Participants with a Negative Result the Previous Year

Background: There is sufficient evidence to show the mortality reduction effect of colorectal cancer (CRC) screening programs using the fecal occult blood test (FOBT). However, we see cases that are found to be advanced CRC despite yearly FOBT screening. Methods: The aim of this study was to investigate the characteristics of advanced CRC detected by a fecal immunochemical test (FIT) screening program in participants with a negative screening result the previous year, which we call “Negative advanced CRC”. A total of 109,639 participants (10.0% required colonoscopy, of whom 76.9% received one) underwent a CRC screening program using a FIT from fiscal 2009 to 2017. Negative advanced CRC was compared with advanced CRC (First advanced CRC) found at the first visit in a person who had not had a FIT screening history for more than 3 years. In addition, we compared the characteristics of Negative advanced CRC with those of interval cancer: cancer cases detected after a negative screening result and before the date of the next recommended screening. Results: A total of 339 cases of CRC (175 male: 164 female, 173 early stage: 166 advanced stage) were detected in the nine-year CRC screening period. The rate of right-sided CRCs was significantly higher in female (P < 0.01), advanced stage (P < 0.01), negative result previous year (P < 0.01), and symptom-negative (P < 0.01) participants than in each counterpart, respectively. The ratio of female (22/35; 62.9%) patients in Negative advanced CRCs tended to be high compared with that (40/83; 48.2%) in First advanced CRCs (P = 0.145). Overall, 22 (62.9%) of 35 Negative advanced CRCs and 28 (33.7%) of 83 First advanced CRCs were located in the right-sided colon, and the rate was significantly higher in Negative advanced CRCs (P < 0.01). In addition, the frequency of female patients was significantly higher in right-sided Negative advanced CRCs than in right-sided First advanced CRCs (P = 0.03). Conclusion: The characteristics of Negative advanced CRC cases (female and right-sided colon) were similar to those of interval cancer reported so far. In the future, it will be necessary to introduce a screening program that is highly sensitive to right-sided CRC

Adrenomedullin in peritoneal effluent expressed by peritoneal mesothelial cells

BACKGROUND: Adrenomedullin (AM) possesses vasodilative and cell-protective properties. Glycine combines with the C-terminal of AM to form mature, physiologically active AM (mAM). AM is reportedly induced by high glucose condition in vascular endothelial or smooth muscle cells; however, little is known on how AM is activated by amidation. To investigate the behavior of AM in patients undergoing peritoneal dialysis (PD), the concentrations of AM, mAM and CA125 were measured. The mAM to AM ratio (mAM/AM ratio) was also evaluated as a marker of amidation activity. METHODS: Twenty patients were recruited for this study. The effluent at the time of the peritoneal equilibration test was collected and AM, mAM and CA125 concentrations were measured. The expression of AM in peritoneal mesothelial cells (PMCs) collected from effluent was also examined with an indirect immunofluorescent method. RESULTS: Mean values of AM and mAM in effluent were 18.1 ± 1.6 and 4.1 ± 0.3 fmol/mL, respectively. In plasma, they were 42.6 ± 3.3 and 5.6 ± 0.6 fmol/mL, respectively. AM concentrations in effluent did not correlate with plasma AM level but correlated well with the dialysate-to-plasma ratio of creatinine (D/P ratio of creatinine). Moreover, in 7 of 20 cases, concentrations of the mAM and mAM/AM ratio in effluent were higher than in plasma. In effluent, AM concentration but not the mAM/AM ratio correlated with CA125 concentration. Immunocytological study revealed diffuse, cytoplasmic expression of AM in PMCs which were collected from effluent during PD. CONCLUSION: AM is expressed by PMCs and actively amidated in the abdominal cavity of patients undergoing PD

Strong atomic ordering in Gd-doped GaN

Gd-doped GaN (Ga 1-xGd xN) thin films were grown on a GaN(001) template by radio frequency plasma-assisted molecular beam epitaxy and characterized by means of x-ray diffraction (XRD) and transmission electron microscopy (TEM). Three samples with a different Gd composition were prepared in this study: x = 0.02, 0.05, and 0.08. XRD and TEM results revealed that the low Gd concentration GaN possesses the wurtzite structure. On the other hand, it was found that an ordered phase with a quadruple-periodicity along the [001] direction in the wurtzite structure is formed throughout the film with x = 0.08. We proposed the atomistic model for the superlattice structure observed here. © 2012 American Institute of Physics.Manabu Ishimaru, Kotaro Higashi, Shigehiko Hasegawa, Hajime Asahi, Kazuhisa Sato, and Toyohiko J. Konno, "Strong atomic ordering in Gd-doped GaN", Appl. Phys. Lett. 101, 101912 (2012) https://doi.org/10.1063/1.4751245

Исследование процесса утилизации сточных вод фабрики по переработке ильменитового концентрата, производительностью 10000 т/год по концентрату

Объектом исследования является процесса утилизации сточных вод фабрики по переработке ильменитового концентрата производительностью 10000 т/год по концентрату. Цель работы – спроектировать участок очистки технической воды. В процессе исследования проводились эксперименты по выпариванию раствора фторид аммония. В результате исследования определены оптимальные параметры введения процесса. Рaссчитaны основные технико-экономические покaзaтели (себестоимость переделa 108294133,24)The object of research is the process of recycling waste water plant for the processing of ilmenite concentrate capacity of 10,000 tons / year for the concentrate. The purpose of the work - design of industrial water purification station. The study carried out experiments on the evaporation of a solution of ammonium fluoride. The study determined the optimal parameters of the process of administration. Rasschitany basic technical and economic pokazateli (peredela 108,294,133.24 cost