Boundary Spanning in Academia: Antecedents and Near-Term Consequences of Academic Entrepreneurialism

Analyzing the pathways of people who earned interdisciplinary research doctorates in the United States in 2010, we generate three main findings while controlling for gender, ethnicity, discipline, and age. First, individuals who complete an interdisciplinary dissertation display near-term income risk since they tend to earn nearly $1,700 less in the year after graduation. Second, students whose fathers earned a college degree demonstrated a .8% higher probability of pursuing interdisciplinary research. Third, the probability that non-citizens pursue interdisciplinary dissertation work is 4.7% higher when compared with US citizens. Our findings quantify the risks of interdisciplinary work and contribute to policy debates

Ultrasensitive bioluminescent determinations of adenosine triphosphate (ATP) for investigating the energetics of host-grown microbes

Stability and optimal concentrations of reagents were studied in bioluminescence assay of ATP levels. Luciferase enzyme was prepared and purified using Sephadex G-100. Interdependencies between enzyme and luciferin concentrations in presence of optimal Mg are illustrated. Optimal ionic strength was confirmed to be 0.05 M for the four buffers tested. Adapted features of the R- and H-systems are summarized, as well as the percentages of ATP pools released from representative microbes by heat and chloroform

Energetics of the host-dependent Mycobacterium Lepraemurium during transition to a capacity for extracellular growth

The ATP measurements were refined to a point where the growth potential of microscopic samples of host-dependent microbes can be measured, even before an increase in microbial numbers has occurred. This tool differs from other biochemical indicators of physiologic states in its sensitivity and in the fact that it can be exploited with unwashed host-dependent and host-grown organisms

Causal contribution and dynamical encoding in the striatum during evidence accumulation.

A broad range of decision-making processes involve gradual accumulation of evidence over time, but the neural circuits responsible for this computation are not yet established. Recent data indicate that cortical regions that are prominently associated with accumulating evidence, such as the posterior parietal cortex and the frontal orienting fields, may not be directly involved in this computation. Which, then, are the regions involved? Regions that are directly involved in evidence accumulation should directly influence the accumulation-based decision-making behavior, have a graded neural encoding of accumulated evidence and contribute throughout the accumulation process. Here, we investigated the role of the anterior dorsal striatum (ADS) in a rodent auditory evidence accumulation task using a combination of behavioral, pharmacological, optogenetic, electrophysiological and computational approaches. We find that the ADS is the first brain region known to satisfy the three criteria. Thus, the ADS may be the first identified node in the network responsible for evidence accumulation