8,637 research outputs found
Analytical method for designing grating compensated dispersion-managed soliton systems
This paper was published in Journal of Optical Society of America B and is made available as an electronic reprint with the permission of OSA. The paper can be found at the following URL on the OSA website: http://www.opticsinfobase.org/abstract.cfm?URI=JOSAB-21-4-706. Systematic or multiple reproduction or distribution to multiple locations via electronic or other means is prohibited and is subject to penalties under law. © 2004 The Optical Society.Peer reviewedPublisher PD
Coarse-Grained MD Simulations Reveal Beta-Amyloid Fibrils of Various Sizes Bind to Interfacial Liquid-Ordered and Liquid-Disordered Regions in Phase Separated Lipid Rafts with Diverse Membrane-Bound Conformational States
The membrane binding behaviors of beta-amyloid fibrils, dimers to pentamers, from solution to lipid raft surfaces, were investigated using coarse-grained (CG) MD simulations. Our CG rafts contain phospholipid, cholesterol (with or without tail- or headgroup modifications), and with or without asymmetrically distributed monosialotetrahexosylganglioside (GM1). All rafts exhibited liquid-ordered (Lo), liquid-disordered (Ld), and interfacial Lo/Ld (Lod) domains, with domain sizes depending on cholesterol structure. For rafts without GM1, all fibrils bound to the Lod domains. Specifically, dimer fibrils bound exclusively via the C-terminal, while larger fibrils could bind via other protein regions. Interestingly, a membrane-inserted state was detected for a trimer fibril in a raft with tail-group modified cholesterol. For rafts containing GM1, fibrils bound either to the GM1-clusters, with numerous membrane-bound conformations, or to the non-GM1-containing-Lod domains via the C-terminal. Our results indicate beta-amyloid fibrils bind to Lod domains or GM1, with diversified membrane-bound conformations, in structurally heterogeneous lipid membranes
Halo Sampling, Local Bias and Loop Corrections
We develop a new test of local bias, by constructing a locally biased halo
density field from sampling the dark matter-halo distribution. Our test differs
from conventional tests in that it preserves the full scatter in the bias
relation and it does not rely on perturbation theory. We put forward that bias
parameters obtained using a smoothing scale R can only be applied to computing
the halo power spectrum at scales k ~ 1/R. Our calculations can automatically
include the running of bias parameters and give vanishingly small loop
corrections at low-k. Our proposal results in much better agreement of the
sampling and perturbation theory results with simulations. In particular,
unlike the standard interpretation of local bias in the literature, our
treatment of local bias does not generate a constant power in the low-k limit.
We search for extra noise in the Poisson corrected halo power spectrum at
wavenumbers below its turn-over and find no evidence of significant positive
noise (as predicted by the standard interpretation) while we find evidence of
negative noise coming from halo exclusion for very massive halos. Using
perturbation theory and our non-perturbative sampling technique we also
demonstrate that nonlocal bias effects discovered recently in simulations
impact the power spectrum only at the few percent level in the weakly nonlinear
regime.Comment: 25 pages, 14 figures; V2: significant revision including more details
about halo exclusion and low-k noise. Conclusions unchange
Measurement of Cosmic-ray Muons and Muon-induced Neutrons in the Aberdeen Tunnel Underground Laboratory
We have measured the muon flux and production rate of muon-induced neutrons
at a depth of 611 m water equivalent. Our apparatus comprises three layers of
crossed plastic scintillator hodoscopes for tracking the incident cosmic-ray
muons and 760 L of gadolinium-doped liquid scintillator for producing and
detecting neutrons. The vertical muon intensity was measured to be cmssr. The yield of
muon-induced neutrons in the liquid scintillator was determined to be
neutrons/(gcm). A fit to the recently measured neutron
yields at different depths gave a mean muon energy dependence of for liquid-scintillator targets.Comment: 14 pages, 17 figures, 3 table
Gravity and Large-Scale Non-local Bias
The relationship between galaxy and matter overdensities, bias, is most often
assumed to be local. This is however unstable under time evolution, we provide
proofs under several sets of assumptions. In the simplest model galaxies are
created locally and linearly biased at a single time, and subsequently move
with the matter (no velocity bias) conserving their comoving number density (no
merging). We show that, after this formation time, the bias becomes unavoidably
non-local and non-linear at large scales. We identify the non-local
gravitationally induced fields in which the galaxy overdensity can be expanded,
showing that they can be constructed out of the invariants of the deformation
tensor (Galileons). In addition, we show that this result persists if we
include an arbitrary evolution of the comoving number density of tracers. We
then include velocity bias, and show that new contributions appear, a dipole
field being the signature at second order. We test these predictions by
studying the dependence of halo overdensities in cells of fixed matter density:
measurements in simulations show that departures from the mean bias relation
are strongly correlated with the non-local gravitationally induced fields
identified by our formalism. The effects on non-local bias seen in the
simulations are most important for the most biased halos, as expected from our
predictions. The non-locality seen in the simulations is not fully captured by
assuming local bias in Lagrangian space. Accounting for these effects when
modeling galaxy bias is essential for correctly describing the dependence on
triangle shape of the galaxy bispectrum, and hence constraining cosmological
parameters and primordial non-Gaussianity. We show that using our formalism we
remove an important systematic in the determination of bias parameters from the
galaxy bispectrum, particularly for luminous galaxies. (abridged)Comment: 26 pages, 9 figures. v2: improved appendix
Heisenberg-picture approach to the exact quantum motion of a time-dependent forced harmonic oscillator
In the Heisenberg picture, the generalized invariant and exact quantum
motions are found for a time-dependent forced harmonic oscillator. We find the
eigenstate and the coherent state of the invariant and show that the
dispersions of these quantum states do not depend on the external force. Our
formalism is applied to several interesting cases.Comment: 15 pages, two eps files, to appear in Phys. Rev. A 53 (6) (1996
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