Novel Scaling Behavior for the Multiplicity Distribution under Second-Order Quark-Hadron Phase Transition

Deviation of the multiplicity distribution $P_q$ in small bin from its Poisson counterpart $p_q$ is studied within the Ginzburg-Landau description for second-order quark-hadron phase transition. Dynamical factor $d_q\equiv P_q/p_q$ for the distribution and ratio $D_q\equiv d_q/d_1$ are defined, and novel scaling behaviors between $D_q$ are found which can be used to detect the formation of quark-gluon plasma. The study of $d_q$ and $D_q$ is also very interesting for other multiparticle production processes without phase transition.Comment: 4 pages in revtex, 5 figures in eps format, will be appeared in Phys. Rev.

Factorial Moments of Continuous Order

The normalized factorial moments $F_q$ are continued to noninteger values of the order $q$, satisfying the condition that the statistical fluctuations remain filtered out. That is, for Poisson distribution $F_q = 1$ for all $q$. The continuation procedure is designed with phenomenology and data analysis in mind. Examples are given to show how $F_q$ can be obtained for positive and negative values of $q$. With $q$ being continuous, multifractal analysis is made possible for multiplicity distributions that arise from self-similar dynamics. A step-by-step procedure of the method is summarized in the conclusion.Comment: 15 pages + 9 figures (figures available upon request), Late

Automation in cell and gene therapy manufacturing:from past to future

As more and more cell and gene therapies are being developed and with the increasing number of regulatory approvals being obtained, there is an emerging and pressing need for industrial translation. Process efficiency, associated cost drivers and regulatory requirements are issues that need to be addressed before industrialisation of cell and gene therapies can be established. Automation has the potential to address these issues and pave the way towards commercialisation and mass production as it has been the case for ‘classical’ production industries. This review provides an insight into how automation can help address the manufacturing issues arising from the development of large-scale manufacturing processes for modern cell and gene therapy. The existing automated technologies with applicability in cell and gene therapy manufacturing are summarized and evaluated here

The random case of Conley's theorem: III. Random semiflow case and Morse decomposition

In the first part of this paper, we generalize the results of the author \cite{Liu,Liu2} from the random flow case to the random semiflow case, i.e. we obtain Conley decomposition theorem for infinite dimensional random dynamical systems. In the second part, by introducing the backward orbit for random semiflow, we are able to decompose invariant random compact set (e.g. global random attractor) into random Morse sets and connecting orbits between them, which generalizes the Morse decomposition of invariant sets originated from Conley \cite{Con} to the random semiflow setting and gives the positive answer to an open problem put forward by Caraballo and Langa \cite{CL}.Comment: 21 pages, no figur

Criticality, Fractality and Intermittency in Strong Interactions

Assuming a second-order phase transition for the hadronization process, we attempt to associate intermittency patterns in high-energy hadronic collisions to fractal structures in configuration space and corresponding intermittency indices to the isothermal critical exponent at the transition temperature. In this approach, the most general multidimensional intermittency pattern, associated to a second-order phase transition of the strongly interacting system, is determined, and its relevance to present and future experiments is discussed.Comment: 15 pages + 2 figures (available on request), CERN-TH.6990/93, UA/NPPS-5-9

Atmospheric dynamics over Europe during the Younger Dryas revealed by palaeoglaciers

A dataset of 120 palaeoglaciers ranging from Morocco in the south to Svalbard in the north and from Ireland in the west to Turkey in the east, has been assembled from the literature. A robust quality control on the chronology was undertaken and, when derived from cosmogenic nuclides, ages were recalculated using the most up-to-date production rates. All the reconstructed glaciers date to the Younger Dryas. Frontal moraines/limits were used to initiate the palaeoglacier reconstructions using GlaRe, a GIS tool which generates an equilibrium profile ice surface along a single flowline and extrapolates this to out to a 3D ice surface. From the resulting glacier surfaces palaeo-ELAs were calculated within the GIS. Where multiple glaciers were reconstructed within in a region, a single ELA value was generated. Results show that ELAs decrease with latitude but have a more complex pattern with longitude. A database of 121 sites, spanning the same geographical range as the palaeoglaciers, was compiled for Younger Dryas temperature, determined from palaeoproxies, for example pollen, diatoms, coleoptera, chironimids etc. These proxy data were merged and interpolated to generate maps of average temperature for the warmest and coldest months and annual average temperature. Results show that, in general, temperature decreases with latitude. Temperature at the palaeo-ELAs were determined from the temperature maps using a lapse rate of 0.65C/100m and the precipitation required for equilibrium was calculated. Positive precipitation anomalies are found along much of the western seaboard of Europe, with the most striking positive anomalies present in the eastern Mediterranean. Negative precipitation anomalies appear on the northern side of the Alps. This pattern is interpreted to represent a southward displaced polar frontal jet stream with a concomitant track of Atlantic midlatitude depressions, leading to more frequent incursions of low pressure systems especially over the relatively warm eastern Mediterranean, enhancing cyclogenesis. This is similar to the modern Scandinavia (SCAND) pattern which, in its positive phase, is characterised by a high pressure anomaly over Fennoscandia and western Russia, negative pressure anomalies around the Iberian Peninsula and enhanced cyclogenesis in the central and eastern Mediterranean. During the YD the Fennoscandian Ice Sheet and permafrost across much of northern continental Europe and Russia would have generated a high pressure region leading to a persistent, enhanced SCAND circulation

Gauge-boson propagator in out of equilibrium quantum-field system and the Boltzmann equation

We construct from first principles a perturbative framework for studying nonequilibrium quantum-field systems that include gauge bosons. The system of our concern is quasiuniform system near equilibrium or nonequilibrium quasistationary system. We employ the closed-time-path formalism and use the so-called gradient approximation. No further approximation is introduced. We construct a gauge-boson propagator, with which a well-defined perturbative framework is formulated. In the course of construction of the framework, we obtain the generalized Boltzmann equation (GBE) that describes the evolution of the number-density functions of gauge-bosonic quasiparticles. The framework allows us to compute the reaction rate for any process taking place in the system. Various processes, in turn, cause an evolution of the systems, which is described by the GBE.Comment: 28 page

Factorial Moments in a Generalized Lattice Gas Model

We construct a simple multicomponent lattice gas model in one dimension in which each site can either be empty or occupied by at most one particle of any one of $D$ species. Particles interact with a nearest neighbor interaction which depends on the species involved. This model is capable of reproducing the relations between factorial moments observed in high--energy scattering experiments for moderate values of $D$. The factorial moments of the negative binomial distribution can be obtained exactly in the limit as $D$ becomes large, and two suitable prescriptions involving randomly drawn nearest neighbor interactions are given. These results indicate the need for considerable care in any attempt to extract information regarding possible critical phenomena from empirical factorial moments.Comment: 15 pages + 1 figure (appended as postscript file), REVTEX 3.0, NORDITA preprint 93/4