6,503 research outputs found

    The role of follow-on contracts in government-sponsored research and development

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    Role of follow-on contracts in government sponsored research and developmen

    Analysis of Absorbing Times of Quantum Walks

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    Quantum walks are expected to provide useful algorithmic tools for quantum computation. This paper introduces absorbing probability and time of quantum walks and gives both numerical simulation results and theoretical analyses on Hadamard walks on the line and symmetric walks on the hypercube from the viewpoint of absorbing probability and time.Comment: LaTeX2e, 14 pages, 6 figures, 1 table, figures revised, references added, to appear in Physical Review

    A microfluidic chip based model for the study of full thickness human intestinal tissue using dual flow

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    © 2016 Author(s). The study of inflammatory bowel disease, including Ulcerative Colitis and Crohn's Disease, has relied largely upon the use of animal or cell culture models; neither of which can represent all aspects of the human pathophysiology. Presented herein is a dual flow microfluidic device which holds full thickness human intestinal tissue in a known orientation. The luminal and serosal sides are independently perfused ex vivo with nutrients with simultaneous waste removal for up to 72 h. The microfluidic device maintains the viability and integrity of the tissue as demonstrated through Haematoxylin & Eosin staining, immunohistochemistry and release of lactate dehydrogenase. In addition, the inflammatory state remains in the tissue after perfusion on the device as determined by measuring calprotectin levels. It is anticipated that this human model will be extremely useful for studying the biology and tes ting novel interventions in diseased tissue

    Boundary Terms, Variational Principles and Higher Derivative Modified Gravity

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    We discuss the criteria that must be satisfied by a well-posed variational principle. We clarify the role of Gibbons-Hawking-York type boundary terms in the actions of higher derivative models of gravity, such as F(R) gravity, and argue that the correct boundary terms are the naive ones obtained though the correspondence with scalar-tensor theory, despite the fact that variations of normal derivatives of the metric must be fixed on the boundary. We show in the case of F(R) gravity that these boundary terms reproduce the correct ADM energy in the hamiltonian formalism, and the correct entropy for black holes in the semi-classical approximation.Comment: 54 pages, 2 figures. Several typos corrected, references added. Version appearing in PR

    An algorithm for counting circuits: application to real-world and random graphs

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    We introduce an algorithm which estimates the number of circuits in a graph as a function of their length. This approach provides analytical results for the typical entropy of circuits in sparse random graphs. When applied to real-world networks, it allows to estimate exponentially large numbers of circuits in polynomial time. We illustrate the method by studying a graph of the Internet structure.Comment: 7 pages, 3 figures, minor corrections, accepted versio

    Experimental study of fusion neutron and proton yields produced by petawatt-laser-irradiated D2-3He or CD4-3He clustering gases

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    We report on experiments in which the Texas Petawatt laser irradiated a mixture of deuterium or deuterated methane clusters and helium-3 gas, generating three types of nuclear fusion reactions: D(d, 3He)n, D(d, t)p and 3He(d, p)4He. We measured the yields of fusion neutrons and protons from these reactions and found them to agree with yields based on a simple cylindrical plasma model using known cross sections and measured plasma parameters. Within our measurement errors, the fusion products were isotropically distributed. Plasma temperatures, important for the cross sections, were determined by two independent methods: (1) deuterium ion time-of-flight, and (2) utilizing the ratio of neutron yield to proton yield from D(d, 3He)n and 3He(d, p)4He reactions, respectively. This experiment produced the highest ion temperature ever achieved with laser-irradiated deuterium clusters.Comment: 16 pages, 6 figure
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