The hippocampus and visual perception

In this review, we will discuss the idea that the hippocampus may be involved in both memory and perception, contrary to theories that posit functional and neuroanatomical segregation of these processes. This suggestion is based on a number of recent neuropsychological and functional neuroimaging studies that have demonstrated that the hippocampus is involved in the visual discrimination of complex spatial scene stimuli. We argue that these findings cannot be explained by long-term memory or working memory processing or, in the case of patient findings, dysfunction beyond the medial temporal lobe (MTL). Instead, these studies point toward a role for the hippocampus in higher-order spatial perception. We suggest that the hippocampus processes complex conjunctions of spatial features, and that it may be more appropriate to consider the representations for which this structure is critical, rather than the cognitive processes that it mediates

Sustained response after a 2-year course of lamivudine treatment of hepatitis B e antigen-negative chronic hepatitis B

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/72882/1/j.1365-2893.2004.00556.x.pd

Living IoT: A Flying Wireless Platform on Live Insects

Sensor networks with devices capable of moving could enable applications ranging from precision irrigation to environmental sensing. Using mechanical drones to move sensors, however, severely limits operation time since flight time is limited by the energy density of current battery technology. We explore an alternative, biology-based solution: integrate sensing, computing and communication functionalities onto live flying insects to create a mobile IoT platform. Such an approach takes advantage of these tiny, highly efficient biological insects which are ubiquitous in many outdoor ecosystems, to essentially provide mobility for free. Doing so however requires addressing key technical challenges of power, size, weight and self-localization in order for the insects to perform location-dependent sensing operations as they carry our IoT payload through the environment. We develop and deploy our platform on bumblebees which includes backscatter communication, low-power self-localization hardware, sensors, and a power source. We show that our platform is capable of sensing, backscattering data at 1 kbps when the insects are back at the hive, and localizing itself up to distances of 80 m from the access points, all within a total weight budget of 102 mg.Comment: Co-primary authors: Vikram Iyer, Rajalakshmi Nandakumar, Anran Wang, In Proceedings of Mobicom. ACM, New York, NY, USA, 15 pages, 201

Light, alertness, and alerting effects of white light:A literature overview

Light is known to elicit non-image-forming responses, such as effects on alertness. This has been reported especially during light exposure at night. Nighttime results might not be translatable to the day. This article aims to provide an overview of (1) neural mechanisms regulating alertness, (2) ways of measuring and quantifying alertness, and (3) the current literature specifically regarding effects of different intensities of white light on various measures and correlates of alertness during the daytime. In general, the present literature provides inconclusive results on alerting effects of the intensity of white light during daytime, particularly for objective measures and correlates of alertness. However, the various research paradigms employed in earlier studies differed substantially, and most studies tested only a limited set of lighting conditions. Therefore, the alerting potential of exposure to more intense white light should be investigated in a systematic, dose-dependent manner with multiple correlates of alertness and within one experimental paradigm over the course of day

Semiclassical theory of electron drag in strong magnetic fields

We present a semiclassical theory for electron drag between two parallel two-dimensional electron systems in a strong magnetic field, which provides a transparent picture of the most salient qualitative features of anomalous drag phenomena observed in recent experiments, especially the striking sign reversal of drag at mismatched densities. The sign of the drag is determined by the curvature of the effective dispersion relation obeyed by the drift motion of the electrons in a smooth disorder potential. Localization plays a role in explaining activated low temperature behavior, but is not crucial for anomalous drag per se.Comment: 10 page

Influences of dynamical disruptions on the evolution of pulsars in globular clusters

By comparing the physical properties of pulsars hosted by core-collapsed (CCed) and non-core-collapsed (Non-CCed) globular clusters (GCs), we find that pulsars in CCed GCs rotate significantly slower than their counterparts in Non-CCed GCs. Additionally, radio luminosities at 1.4 GHz in CCed GCs are higher. These findings are consistent with the scenario that dynamical interactions in GCs can interrupt angular momentum transfer processes and surface magnetic field decay during the recycling phase. Our results suggest that such effects in CCed GCs are stronger due to more frequent disruptions of compact binaries. This is further supported by the observation that both estimated disruption rates and the fraction of isolated pulsars are predominantly higher in CCed GCs.Comment: 9 pages, 8 figures, 3 tables, Accepted in MNRA

Scanning-probe spectroscopy of semiconductor donor molecules

Semiconductor devices continue to press into the nanoscale regime, and new applications have emerged for which the quantum properties of dopant atoms act as the functional part of the device, underscoring the necessity to probe the quantum structure of small numbers of dopant atoms in semiconductors[1-3]. Although dopant properties are well-understood with respect to bulk semiconductors, new questions arise in nanosystems. For example, the quantum energy levels of dopants will be affected by the proximity of nanometer-scale electrodes. Moreover, because shallow donors and acceptors are analogous to hydrogen atoms, experiments on small numbers of dopants have the potential to be a testing ground for fundamental questions of atomic and molecular physics, such as the maximum negative ionization of a molecule with a given number of positive ions[4,5]. Electron tunneling spectroscopy through isolated dopants has been observed in transport studies[6,7]. In addition, Geim and coworkers identified resonances due to two closely spaced donors, effectively forming donor molecules[8]. Here we present capacitance spectroscopy measurements of silicon donors in a gallium-arsenide heterostructure using a scanning probe technique[9,10]. In contrast to the work of Geim et al., our data show discernible peaks attributed to successive electrons entering the molecules. Hence this work represents the first addition spectrum measurement of dopant molecules. More generally, to the best of our knowledge, this study is the first example of single-electron capacitance spectroscopy performed directly with a scanning probe tip[9].Comment: In press, Nature Physics. Original manuscript posted here; 16 pages, 3 figures, 5 supplementary figure

Sign-reversal of drag in bilayer systems with in-plane periodic potential modulation

We develop a theory for describing frictional drag in bilayer systems with in-plane periodic potential modulations, and use it to investigate the drag between bilayer systems in which one of the layers is modulated in one direction. At low temperatures, as the density of carriers in the modulated layer is changed, we show that the transresistivity component in the direction of modulation can change its sign. We also give a physical explanation for this behavior.Comment: 4 pages, 4 figure

Multi-Wavelength Observations Of A New Redback Millisecond Pulsar 4FGL J1910.7-5320

We present the study of multi-wavelength observations of an unidentified Fermi Large Area Telescope (LAT) source, 4FGL J1910.7-5320, a new candidate redback millisecond pulsar binary. In the 4FGL 95% error region of 4FGL J1910.7-5320, we find a possible binary with a 8.36-hr orbital period from the Catalina Real-Time Transient Survey (CRTS), confirmed by optical spectroscopy using the SOAR telescope. This optical source was recently independently discovered as a redback pulsar by the TRAPUM project, confirming our prediction. We fit the optical spectral energy distributions of 4FGL J1910.7-5320 with a blackbody model, inferring a maximum distance of 4.1 kpc by assuming that the companion fills its Roche-lobe with a radius of R = 0.7R_sun. Using a 12.6 ks Chandra X-ray observation, we identified an X-ray counterpart for 4FGL J1910.7-5320, with a spectrum that can be described by an absorbed power-law with a photon index of 1.0+/-0.4. The spectrally hard X-ray emission shows tentative evidence for orbital variability. Using more than 12 years of Fermi-LAT data, we refined the position of the {\gamma}-ray source, and the optical candidate still lies within the 68% positional error circle. In addition to 4FGL J1910.7-5320, we find a variable optical source with a periodic signal of 4.28-hr inside the 4FGL catalog 95% error region of another unidentified Fermi source, 4FGL J2029.5-4237. However, the {\gamma}-ray source does not have a significant X-ray counterpart in a 11.7 ks Chandra observation, with a 3-{\sigma} flux upper limit of 2.4*10^-14 erg cm^-2 s^-1 (0.3-7 keV). Moreover, the optical source is outside our updated Fermi-LAT 95% error circle. These observational facts all suggest that this new redback millisecond pulsar powers the {\gamma}-ray source 4FGL J1910.7-5320 while 4FGL J2029.5-4237 is unlikely the {\gamma}-ray counterpart to the 4.28-hr variable.Comment: Accepted for publication in Ap