Extreme H isotopic anomalies in chondritic organic matter

Extract from introduction: We have conducted ionprobe (IMS6f and NanoSIMS) imaging studies of various samples for H, D, C, 14N and 15N. These will ultimately be correlated with micro-analytic techniques such as FIB/TEM or STXM/XANES. We analyzed matrix fragments from Bells (CM2), Al Rais (CR2) and Tagish Lake (unique) [2], high purity insoluble organic matter (IOM) [3] extracted from EET92042 (“EET”, CR2), Bells, Murchison (CM2), Allende (CV3), Krymka (LL3.1) and, for comparison, 3 IDPs

Influence of peptidylarginine deiminase type 4 genotype and shared epitope on clinical characteristics and autoantibody profile of rheumatoid arthritis.

Background: Recent evidence suggests that distinction of subsets of rheumatoid arthritis (RA) depending on anticyclic citrullinated peptide antibody (anti-CCP) status may be helpful in distinguishing distinct aetiopathologies and in predicting the course of disease. HLA-DRB1 shared epitope (SE) and peptidylarginine deiminase type 4 (PADI4) genotype, both of which have been implicated in anti-CCP generation, are assumed to be associated with RA. Objectives: To elucidate whether PADI4 affects the clinical characteristics of RA, and whether it would modulate the effect of anti-CCPs on clinical course. The combined effect of SE and PADI4 on autoantibody profile was also analysed. Methods: 373 patients with RA were studied. SE, padi4_94C.T, rheumatoid factor, anti-CCPs and antinuclear antibodies (ANAs) were determined. Disease severity was characterised by cumulative therapy intensity classified into ordinal categories (CTI-1 to CTI-3) and by Steinbrocker score. Results: CTI was significantly associated with disease duration, erosive disease, disease activity score (DAS) 28 and anti-CCPs. The association of anti-CCPs with CTI was considerably influenced by padi4_94C.T genotype (C/C: ORadj=0.93, padj=0.92; C/T: ORadj=2.92, padj=0.093; T/T: ORadj=15.3, padj=0.002). Carriage of padi4_94T exhibited a significant trend towards higher Steinbrocker scores in univariate and multivariate analyses. An association of padi4_94C.T with ANAs was observed, with noteworthy differences depending on SE status (SE2: ORadj=6.20, padj,0.04; SE+: ORadj=0.36, padj=0.02) and significant heterogeneity between the two SE strata (p=0.006). Conclusions: PADI4 genotype in combination with anti- CCPs and SE modulates clinical and serological characteristics of RA

Were Presolar Grains Destroyed by the Nebular Process Responsible for the Volatile Element Fractionation?

We present SiC abundances from a number of CM and CR chondrites using NanoSIMS raster ion imaging of acid residues. We find higher SiC abundances for CRs than previously estimated based on noble gases

Charge Fluctuations in the Edge States of N-S hybrid Nano-Structures

In this work we show how to calculate the equilibrium and non-equilibrium charge fluctuations in a gated normal mesoscopic conductor which is attached to one normal lead and one superconducting lead. We then consider an example where the structure is placed in a high magnetic field, such that the transport is dominated by edge states. We calculate the equilibrium and non-equilibrium charge fluctuations in the gate, for a single edge state, comparing our results to those for the same system, but with two normal leads. We then consider the specific example of a quantum point contact and calculate the charge fluctuations in the gate for more than one edge state.Comment: 4 pages with 1 figure. In published version the high magnetic field dynamics of the holes is treated incorrectly. An erratum is in preparatio

Leveraging multilingual descriptions for link prediction: Initial experiments

In most Knowledge Graphs (KGs), textual descriptions ofentities are provided in multiple natural languages. Additional informa-tion that is not explicitly represented in the structured part of the KGmight be available in these textual descriptions. Link prediction modelswhich make use of entity descriptions usually consider only one language.However, descriptions given in multiple languages may provide comple-mentary information which should be taken into consideration for thetasks such as link prediction. In this poster paper, the benefits of mul-tilingual embeddings for incorporating multilingual entity descriptionsinto the task of link prediction in KGs are investigate

Why Matrix theory works for oddly shaped membranes

We give a simple proof of why there is a Matrix theory approximation for a membrane shaped like an arbitrary Riemann surface. As corollaries, we show that noncompact membranes cannot be approximated by matrices and that the Poisson algebra on any compact phase space is U(infinity). The matrix approximation does not appear to work properly in theories such as IIB string theory or bosonic membrane theory where there is no conserved 3-form charge to which the membranes couple.Comment: 8 pages, 4 figures, revtex; references adde

The Calogero-Moser equation system and the ensemble average in the Gaussian ensembles

From random matrix theory it is known that for special values of the coupling constant the Calogero-Moser (CM) equation system is nothing but the radial part of a generalized harmonic oscillator Schroedinger equation. This allows an immediate construction of the solutions by means of a Rodriguez relation. The results are easily generalized to arbitrary values of the coupling constant. By this the CM equations become nearly trivial. As an application an expansion for in terms of eigenfunctions of the CM equation system is obtained, where X and Y are matrices taken from one of the Gaussian ensembles, and the brackets denote an average over the angular variables.Comment: accepted by J. Phys.

Ordinary differential equations which linearize on differentiation

In this short note we discuss ordinary differential equations which linearize upon one (or more) differentiations. Although the subject is fairly elementary, equations of this type arise naturally in the context of integrable systems.Comment: 9 page