46 research outputs found
Oscillation of Second-Order Nonlinear Delay Dynamic Equations on Time Scales
In this work, we use the generalized Riccati transformation and the inequality technique to establish some new oscillation criteria for the second-order nonlinear delay dynamic equation (p(t)(xΔ(t))Îł)Δ+q(t)f(x(Ď„(t)))=0, on a time scale , where Îł is the quotient of odd positive integers and p(t) and q(t) are positive right-dense continuous (rd-continuous) functions on 𝕋. Our results improve and extend some results established by Sun et al. 2009. Also our results unify the oscillation of the second-order nonlinear delay differential equation and the second-order nonlinear delay difference equation. Finally, we give some examples to illustrate our main results
Oscillation of Second-Order Nonlinear Delay Dynamic Equations with Damping on Time Scales
We use the generalized Riccati transformation and the inequality technique to establish some new oscillation criteria for the second-order nonlinear delay dynamic equation with damping on a time scale T(r(t)g(x(t), xΔ(t)))Δ+p(t)g(x(t), xΔ(t))  + q(t)f(x(τ(t)))=0, where r(t), p(t), and q(t) are positive right dense continuous (rd-continuous) functions on T. Our results improve and extend some results established by Zhang et al., 2011. Also, our results unify the oscillation of the second-order nonlinear delay differential equation with damping and the second-order nonlinear delay difference equation with damping. Finally, we give some examples to illustrate our main results
Technological feasibility and cultural acceptability study of solar power systems for microwave assisted sandstone artisanal mining
This paper investigates the technical feasibility of microwave assisted artisanal mining in the production of Sandstone from QwaQwa in South Africa. It further discusses the cultural acceptability by the rural community of the synergetic application of the emerging technology (microwave energy) and the renewable resource (solar). Sandstone in QwaQwa, Free State is artisanally mined using chisels and hammers. This form of mining is extensively laborious and is normally accompanied by numerous casualties. The paper demonstrates the existence and the possible utilization of alternative methods including emerging technologies which are more productive, efficient, effective and sustainable. The solar energy systems are used to trigger the microwave magnetron which results into high energy microwave dosage. The dosage causes differential or selective heating on the rocks which culminate into rock breaking along the interfacial grain boundaries between the different constituting minerals. The data used in the analysis was collected by administering questionnaires to the artisanal mining community in QwaQwa and from observations made on site as well as desk top information obtained from secondary sources. The paper contributes to knowledge by drawing on the solar energy systems to generate the dosage required to trigger the microwave magnetron used to facilitate a more efficient and economical artisanal mining of sandstones. In conclusion the paper recommends to policy makers the application of microwave energy in mineral artisanal mining and processing instead of the manual chisel and hammer currently being utilized country wide. It then gives a detail analysis of the technical, scheduling and economic analysis of the sandstone artisanal mining in QwaQwa
The evolving SARS-CoV-2 epidemic in Africa: insights from rapidly expanding genomic surveillance
Investment in SARS-CoV-2 sequencing in Africa over the past year has led to a major increase in the number of sequences generated, now exceeding 100,000 genomes, used to track the pandemic on the continent. Our results show an increase in the number of African countries able to sequence domestically, and highlight that local sequencing enables faster turnaround time and more regular routine surveillance. Despite limitations of low testing proportions, findings from this genomic surveillance study underscore the heterogeneous nature of the pandemic and shed light on the distinct dispersal dynamics of Variants of Concern, particularly Alpha, Beta, Delta, and Omicron, on the continent. Sustained investment for diagnostics and genomic surveillance in Africa is needed as the virus continues to evolve, while the continent faces many emerging and re-emerging infectious disease threats. These investments are crucial for pandemic preparedness and response and will serve the health of the continent well into the 21st century
A year of genomic surveillance reveals how the SARS-CoV-2 pandemic unfolded in Africa
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Arbuscular mycorrhizal fungal application to improve growth and tolerance of wheat (Triticum aestivum L.) plants grown in saline soil
A year of genomic surveillance reveals how the SARS-CoV-2 pandemic unfolded in Africa.
The progression of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic in Africa has so far been heterogeneous, and the full impact is not yet well understood. In this study, we describe the genomic epidemiology using a dataset of 8746 genomes from 33 African countries and two overseas territories. We show that the epidemics in most countries were initiated by importations predominantly from Europe, which diminished after the early introduction of international travel restrictions. As the pandemic progressed, ongoing transmission in many countries and increasing mobility led to the emergence and spread within the continent of many variants of concern and interest, such as B.1.351, B.1.525, A.23.1, and C.1.1. Although distorted by low sampling numbers and blind spots, the findings highlight that Africa must not be left behind in the global pandemic response, otherwise it could become a source for new variants
The evolving SARS-CoV-2 epidemic in Africa: Insights from rapidly expanding genomic surveillance.
Investment in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) sequencing in Africa over the past year has led to a major increase in the number of sequences that have been generated and used to track the pandemic on the continent, a number that now exceeds 100,000 genomes. Our results show an increase in the number of African countries that are able to sequence domestically and highlight that local sequencing enables faster turnaround times and more-regular routine surveillance. Despite limitations of low testing proportions, findings from this genomic surveillance study underscore the heterogeneous nature of the pandemic and illuminate the distinct dispersal dynamics of variants of concern-particularly Alpha, Beta, Delta, and Omicron-on the continent. Sustained investment for diagnostics and genomic surveillance in Africa is needed as the virus continues to evolve while the continent faces many emerging and reemerging infectious disease threats. These investments are crucial for pandemic preparedness and response and will serve the health of the continent well into the 21st century
The evolving SARS-CoV-2 epidemic in Africa: Insights from rapidly expanding genomic surveillance
INTRODUCTION
Investment in Africa over the past year with regard to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) sequencing has led to a massive increase in the number of sequences, which, to date, exceeds 100,000 sequences generated to track the pandemic on the continent. These sequences have profoundly affected how public health officials in Africa have navigated the COVID-19 pandemic.
RATIONALE
We demonstrate how the first 100,000 SARS-CoV-2 sequences from Africa have helped monitor the epidemic on the continent, how genomic surveillance expanded over the course of the pandemic, and how we adapted our sequencing methods to deal with an evolving virus. Finally, we also examine how viral lineages have spread across the continent in a phylogeographic framework to gain insights into the underlying temporal and spatial transmission dynamics for several variants of concern (VOCs).
RESULTS
Our results indicate that the number of countries in Africa that can sequence the virus within their own borders is growing and that this is coupled with a shorter turnaround time from the time of sampling to sequence submission. Ongoing evolution necessitated the continual updating of primer sets, and, as a result, eight primer sets were designed in tandem with viral evolution and used to ensure effective sequencing of the virus. The pandemic unfolded through multiple waves of infection that were each driven by distinct genetic lineages, with B.1-like ancestral strains associated with the first pandemic wave of infections in 2020. Successive waves on the continent were fueled by different VOCs, with Alpha and Beta cocirculating in distinct spatial patterns during the second wave and Delta and Omicron affecting the whole continent during the third and fourth waves, respectively. Phylogeographic reconstruction points toward distinct differences in viral importation and exportation patterns associated with the Alpha, Beta, Delta, and Omicron variants and subvariants, when considering both Africa versus the rest of the world and viral dissemination within the continent. Our epidemiological and phylogenetic inferences therefore underscore the heterogeneous nature of the pandemic on the continent and highlight key insights and challenges, for instance, recognizing the limitations of low testing proportions. We also highlight the early warning capacity that genomic surveillance in Africa has had for the rest of the world with the detection of new lineages and variants, the most recent being the characterization of various Omicron subvariants.
CONCLUSION
Sustained investment for diagnostics and genomic surveillance in Africa is needed as the virus continues to evolve. This is important not only to help combat SARS-CoV-2 on the continent but also because it can be used as a platform to help address the many emerging and reemerging infectious disease threats in Africa. In particular, capacity building for local sequencing within countries or within the continent should be prioritized because this is generally associated with shorter turnaround times, providing the most benefit to local public health authorities tasked with pandemic response and mitigation and allowing for the fastest reaction to localized outbreaks. These investments are crucial for pandemic preparedness and response and will serve the health of the continent well into the 21st century
Oscillation of Second-Order Nonlinear Delay Dynamic Equations on Time Scales
In this work, we use the generalized Riccati transformation and the inequality technique to establish some new oscillation criteria for the second-order nonlinear delay dynamic equatio