316 research outputs found

    Uitkomen kuikens in een traditionele vleeskuikenstal

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    This report describes the results of a study where a comparison was made between broilers hatched in the broiler house and in the hatchery. Performance results, carcass yields, litter quality, broiler quality and gait score were measured

    Ontwikkeling van methoden voor het monitoren van voetzoollaesies bij vleeskuikens = Development of methods to monitor foot pad lesions in broiler chickens

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    This report describes different methods for classification and monitoring foot pad dermatitis in broiler chickens, including an automatic system using video imaging

    Leren van collega's

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    Grote verschillen tussen bedrijven in voetzoolproblemen wekken het idee dat kuikenhouders van elkaar kunnen leren. WUR Livestock Research is daar in de praktijk ingedoken

    Overzicht van maatregelen om de ammoniakemissie uit de veehouderij te beperken : Geactualiseerde versie 2017

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    This report gives an overview of measures to reduce ammonia emissions from livestock farming systems. In addition to existing housing measures (as published in the Rav), other (not yet approved in the Rav) housing measures, as well as feed and management measures are discussed. This document focusses on the animal categories cattle (dairy cattle and veal calves), pigs (farrowing sows, piglets, fattening pigs, sows and her piglets) and poultry (laying hens, broiler chickens, broiler breeders)

    PAS Aanvullende reservemaatregelen Landbouw: uitwerking van een quick scan

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    In many Natura 2000 area’s, the nitrogen deposition is higher than wished for. This led to a deadlock in economic development of, among others, livestock husbandry. The interdepartmental program ‘Programma Aanpak Stikstof’ (PAS), is meant to overcome the standstill of grants of permits to produce, while in term preservation goals of nature area’s can be achieved. For the three sector groups Traffic and Transportation, Industry and Energy, and Agriculture source measures are inventoried to deal with the bottlenecks. By order of the Ministry of Economic Affairs this report presents the inventory of measures for agriculture

    Fair and Sound Secret Sharing from Homomorphic Time-Lock Puzzles

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    Achieving fairness and soundness in non-simultaneous rational secret sharing schemes has proved to be challenging. On the one hand, soundness can be ensured by providing side information related to the secret as a check, but on the other, this can be used by deviant players to compromise fairness. To overcome this, the idea of incorporating a time delay was suggested in the literature: in particular, time-delay encryption based on memory-bound functions has been put forth as a solution. In this paper, we propose a different approach to achieve such delay, namely using homomorphic time-lock puzzles (HTLPs), introduced at CRYPTO 2019, and construct a fair and sound rational secret sharing scheme in the non-simultaneous setting from HTLPs. HTLPs are used to embed sub-shares of the secret for a predetermined time. This allows to restore fairness of the secret reconstruction phase, despite players having access to information related to the secret which is required to ensure soundness of the scheme. Key to our construction is the fact that the time-lock puzzles are homomorphic so that players can compactly evaluate sub-shares. Without this efficiency improvement, players would have to independently solve each puzzle sent from the other players to obtain a share of the secret, which would be computationally inefficient. We argue that achieving both fairness and soundness in a non-simultaneous scheme using a time delay based on CPU-bound functions rather than memory-bound functions is more cost effective and realistic in relation to the implementation of the construction

    Personal non-commercial use only

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    ABSTRACT. Objective. To examine (1) the risk of death from cardiovascular disease (CVD) and from all causes in patients with gout who do not undergo urate-lowering therapy (ULT), and (2) the effect of ULT on mortality risk in patients with gout. Methods. In this prospective case-matched cohort study, 40,623 Taiwanese individuals aged ≥ 17 years were followed for 6.5 years. Mortality rate was compared between 1189 patients with gout who did not receive ULT and reference subjects (no gout, no ULT) matched for age, sex, and the index date of gout diagnosis (1:3 patients with gout/reference subjects), and between 764 patients with gout who received ULT and 764 patients with gout who did not receive ULT matched 1-to-1 based on their propensity score and the index date of ULT prescription

    The secreted triose phosphate isomerase of Brugia malayi is required to sustain microfilaria production in vivo

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    Human lymphatic filariasis is a major tropical disease transmitted through mosquito vectors which take up microfilarial larvae from the blood of infected subjects. Microfilariae are produced by long-lived adult parasites, which also release a suite of excretory-secretory products that have recently been subject to in-depth proteomic analysis. Surprisingly, the most abundant secreted protein of adult Brugia malayi is triose phosphate isomerase (TPI), a glycolytic enzyme usually associated with the cytosol. We now show that while TPI is a prominent target of the antibody response to infection, there is little antibody-mediated inhibition of catalytic activity by polyclonal sera. We generated a panel of twenty-three anti-TPI monoclonal antibodies and found only two were able to block TPI enzymatic activity. Immunisation of jirds with B. malayi TPI, or mice with the homologous protein from the rodent filaria Litomosoides sigmodontis, failed to induce neutralising antibodies or protective immunity. In contrast, passive transfer of neutralising monoclonal antibody to mice prior to implantation with adult B. malayi resulted in 60–70% reductions in microfilarial levels in vivo and both oocyte and microfilarial production by individual adult females. The loss of fecundity was accompanied by reduced IFNγ expression by CD4+ T cells and a higher proportion of macrophages at the site of infection. Thus, enzymatically active TPI plays an important role in the transmission cycle of B. malayi filarial parasites and is identified as a potential target for immunological and pharmacological intervention against filarial infections
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