3,776 research outputs found
Foldy-Wouthuysen transformation for a Dirac-Pauli dyon and the Thomas-Bargmann-Michel-Telegdi equation
The classical dynamics for a charged point particle with intrinsic spin is
governed by a relativistic Hamiltonian for the orbital motion and by the
Thomas-Bargmann-Michel-Telegdi equation for the precession of the spin. It is
natural to ask whether the classical Hamiltonian (with both the orbital and
spin parts) is consistent with that in the relativistic quantum theory for a
spin-1/2 charged particle, which is described by the Dirac equation. In the
low-energy limit, up to terms of the 7th order in ( and
is the particle mass), we investigate the Foldy-Wouthuysen (FW) transformation
of the Dirac Hamiltonian in the presence of homogeneous and static
electromagnetic fields and show that it is indeed in agreement with the
classical Hamiltonian with the gyromagnetic ratio being equal to 2. Through
electromagnetic duality, this result can be generalized for a spin-1/2 dyon,
which has both electric and magnetic charges and thus possesses both intrinsic
electric and magnetic dipole moments. Furthermore, the relativistic quantum
theory for a spin-1/2 dyon with arbitrary values of the gyromagnetic and
gyroelectric ratios can be described by the Dirac-Pauli equation, which is the
Dirac equation with augmentation for the anomalous electric and anomalous
magnetic dipole moments. The FW transformation of the Dirac-Pauli Hamiltonian
is shown, up to the 7th order again, to be also in accord with the classical
Hamiltonian.Comment: 18 page
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Increased Hematopoietic Extracellular RNAs and Vesicles in the Lung during Allergic Airway Responses.
Extracellular RNAs (exRNAs) can be released by numerous cell types in vitro, are often protected within vesicles, and can modify recipient cell function. To determine how the composition and cellular sources of exRNAs and the extracellular vesicles (EVs) that carry them change in vivo during tissue inflammation, we analyzed bronchoalveolar lavage fluid (BALF) from mice before and after lung allergen challenge. In the lung, extracellular microRNAs (ex-miRNAs) had a composition that was highly correlated with airway-lining epithelium. Using cell type-specific membrane tagging and single vesicle flow, we also found that 80% of detected vesicles were of epithelial origin. After the induction of allergic airway inflammation, miRNAs selectively expressed by immune cells, including miR-223 and miR-142a, increased and hematopoietic-cell-derived EVs also increased >2-fold. These data demonstrate that infiltrating immune cells release ex-miRNAs and EVs in inflamed tissues to alter the local extracellular environment
On the unitarity of higher-dervative and nonlocal theories
We consider two simple models of higher-derivative and nonlocal quantu
systems.It is shown that, contrary to some claims found in literature, they can
be made unitary.Comment: 8 pages, no figure
Mg-induced increase of band gap in Zn1-xMgxO nanorods revealed by x-ray absorption and emission spectroscopy
[[abstract]]X-rayabsorption near-edge structure (XANES) and x-ray emission spectroscopy (XES) measurements were used to investigate the effect of Mgdoping in ZnOnanorods. The intensities of the features in the O K-edge XANES spectra of Zn1−xMgxOnanorods are lower than those of pure ZnOnanorods, suggesting that Mgdoping increases the negative effective charge of O ions. XES and XANES spectra of O 2p states indicate that Mgdoping raises (lowers) the conduction-band-minimum (valence-band-maximum) and increases the band gap. The band gap is found to increase linearly with the Mg content, as revealed by photoluminescence and combined XANES and XES measurements.[[booktype]]紙本[[booktype]]電子版[[countrycodes]]US
Patchy Interspecific Sequence Similarities Efficiently Identify Positive cis-Regulatory Elements in the Sea Urchin
We demonstrate that interspecific sequence conservation can provide a systematic guide to the identification of functional cis-regulatory elements within a large expanse of genomic DNA. The test was carried out on the otx gene of Strongylocentrotus purpuratus. This gene plays a major role in the gene regulatory network that underlies endomesoderm specification in the embryo. The cis-regulatory organization of the otx gene is expected to be complex, because the gene has three different start sites (X. Li, C.-K. Chuang, C.-A. Mao, L. M. Angerer, and W. H. Klein, 1997, Dev. Biol. 187, 253–266), and it is expressed in many different spatial domains of the embryo. BAC recombinants containing the otx gene were isolated from Strongylocentrotus purpuratus and Lytechinus variegatus libraries, and the ordered sequence of these BACs was obtained and annotated. Sixty kilobases of DNA flanking the gene, and included in the BAC sequence from both species, were scanned computationally for short conserved sequence elements. For this purpose, we used a newly constructed software package assembled in our laboratory, “FamilyRelations.” This tool allows detection of sequence similarities above a chosen criterion within sliding windows set at 20–50 bp. Seventeen partially conserved regions, most a few hundred base pairs long, were amplified from the S. purpuratus BAC DNA by PCR, inserted in an expression vector driving a CAT reporter, and tested for cis-regulatory activity by injection into fertilized S. purpuratus eggs. The regulatory activity of these constructs was assessed by whole-mount in situ hybridization (WMISH) using a probe against CAT mRNA. Of the 17 constructs, 11 constructs displayed spatially restricted regulatory activity, and 6 were inactive in this test. The domains within which the cis-regulatory constructs were expressed are approximately consistent with results from a WMISH study on otx expression in the embryo, in which we used probes specific for the mRNAs generated from each of the three transcription start sites. Four separate cis-regulatory elements that specifically produce endomesodermal expression were identified, as well as ubiquitously active elements, and ectoderm-specific elements. We confirm predictions from other work with respect to target sites for specific transcription factors within the elements that express in the endoderm
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