1,586 research outputs found

    P2-purinergic control of liver glycogenolysis

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    Development of a 3D dynamic flood web GIS visualisation tool

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    Low elevation coastal areas are vulnerable to the effects of sea level rise and to an increase in the frequency and severity of storm surge events due to climate change.Coastal urban areas are at risk because coastal flooding causes extensive damage to energy and transportation infrastructure, disruptions to the delivery of services, devastating tolls on the public’s health and,occasionally, significant loss of life. Although scientists widely stress the compelling need to mitigate and adapt to climate change, public awareness lags behind. Because WebGIS maps (web-based geographic information systems) quickly convey strong messages, condense complex information, engage people on issues of environmental change, and motivate personal actions, this paper focuses on searching the ideal flood assessment WebGIS method to encourage people to mitigate and adapt to climate change. Surveys demonstrated that 3D visualisations have an enormous added value because they are more vivid and therefore more understandable and make it easier to imagine the consequences of a flood than2D visualisations. In this research, the WebGIS will be created using Ol3-Cesium and openlayers to visualise a flood event by dynamic layers in a 2D/3D environment

    Influence of migration on the thought process of individuals at ultra-high risk for psychosis

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    OBJECTIVE To assess the influence of migration on the psychopathological presentation of individuals at ultra-high risk for psychosis (UHR) in São Paulo, Brazil. METHODS This study is part of the Subclinical Symptoms and Prodromal Psychosis (SSAPP) project, a cohort study in São Paulo, Brazil, designed to follow individuals at UHR. After screening with the Prodromal Questionnaire (PQ) and a clinical interview, the Global Assessment of Functioning (GAF) was administered, a neuropsychological assessment was performed, sociodemographic and migration data were obtained. We then analyzed UHR individuals who had migration data to see if migration had any effect on their cognition and psychopathology. Chi-square tests were used for categorical variables, and Student's t test or analysis of variance (ANOVA) were used for nonparametric and parametric distributions, respectively. RESULTS The sample was composed of 42 at-risk subjects, of whom 5 had a migration history in the past two generations. Those with migration history showed significantly more formal thought disturbances (p = 0.012) and sleeping problems (p = 0.033) compared to those without. CONCLUSIONS Our data reinforce migration as a risk factor for psychosis in developing countries as well, and highlights the importance of studying the specific effect of this factor in UHR psychopathology

    Faddeev Calculations of Proton-Deuteron Radiative Capture with Exchange Currents

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    pd capture processes at various energies have been analyzed based on solutions of 3N-Faddeev equations and using modern NN forces. The application of the Siegert theorem is compared to the explicit use of π\pi- and ρ\rho-like exchange currents connected to the AV18 NN interaction. Overall good agreement with cross sections and spin observables has been obtained but leaving room for improvement in some cases. Feasibility studies for 3NF's consistently included in the 3N continuum and the 3N bound state have been performed as well.Comment: Minor changes in notation, ps files for figure

    The placebo effect in the motor domain is differently modulated by the external and internal focus of attention

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    Among the cognitive strategies that can facilitate motor performance in sport and physical practice, a prominent role is played by the direction of the focus of attention and the placebo effect. Consistent evidence converges in indicating that these two cognitive functions can influence the motor outcome, although no study up-to-now tried to study them together in the motor domain. In this explorative study, we combine for the first time these approaches, by applying a placebo procedure to increase force and by manipulating the focus of attention with explicit verbal instructions. Sixty healthy volunteers were asked to perform abduction movements with the index finger as strongly as possible against a piston and attention could be directed either toward the movements of the finger (internal focus, IF) or toward the movements of the piston (external focus, EF). Participants were randomized in 4 groups: two groups underwent a placebo procedure (Placebo-IF and Placebo-EF), in which an inert treatment was applied on the finger with verbal information on its positive effects on force; two groups underwent a control procedure (Control-IF and Control-EF), in which the same treatment was applied with overt information about its inefficacy. The placebo groups were conditioned about the effects of the treatment with a surreptitious amplification of a visual feedback signalling the level of force. During the whole procedure, we recorded actual force, subjective variables and electromyography from the hand muscles. The Placebo-IF group had higher force levels after the procedure than before, whereas the Placebo-EF group had a decrease of force. Electromyography showed that the Placebo-IF group increased the muscle units recruitment without changing the firing rate. These findings show for the first time that the placebo effect in motor performance can be influenced by the subject\u2019s attentional focus, being enhanced with the internal focus of attention
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