1,015 research outputs found

    Optimization of graded multilayer designs for astronomical x-ray telescopes

    Get PDF
    We developed a systematic method for optimizing the design of depth-graded multilayers for astronomical hard-x-ray and soft-γ-ray telescopes based on the instrument’s bandpass and the field of view. We apply these methods to the design of the conical-approximation Wolter I optics employed by the balloon-borne High Energy Focusing Telescope, using W/Si as the multilayer materials. In addition, we present optimized performance calculations of mirrors, using other material pairs that are capable of extending performance to photon energies above the W K-absorption edge (69.5 keV), including Pt/C, Ni/C, Cu/Si, and Mo/Si

    Siberia

    Get PDF
    n/

    253 INHIBITING CALCINEURIN ACTIVITY UNDER PHYSIOLOGICAL CONDITIONS SELECTIVELY PREVENTS ARTICULAR CHONDROCYTE HYPERTROPHY

    Get PDF

    Development of thermally formed glass optics for astronomical hard x-ray telescopes

    Get PDF
    The next major observational advance in hard X-ray/soft gamma-ray astrophysics will come with the implementation of telescopes capable of focusing 10-200 keV radiation. Focusing allows high signal-to-noise imaging and spectroscopic observations of many sources in this band for the first time. The recent development of depth-graded multilayer coatings has made the design of telescopes for this bandpass practical, however the ability to manufacture inexpensive substrates with appropriate surface quality and figure to achieve sub-arcminute performance has remained an elusive goal. In this paper, we report on new, thermally-formed glass micro-sheet optics capable of meeting the requirements of the next-generation of astronomical hard X-ray telescopes

    NASA advanced aeronautics design solar powered remotely piloted vehicle

    Get PDF
    Environmental problems such as the depletion of the ozone layer and air pollution demand a change in traditional means of propulsion that is sensitive to the ecology. Solar powered propulsion is a favorable alternative that is both ecologically harmless as well as cost effective. Integration of solar energy into designs ranging from futuristic vehicles to heating is beneficial to society. The design and construction of a Multi-Purpose Remotely Piloted Vehicle (MPRPV) seeks to verify the feasibility of utilizing solar propulsion as a primary fuel source. This task has been a year long effort by a group of ten students, divided into five teams, each dealing with different aspects of the design. The aircraft was designed to take-off, climb to the design altitude, fly in a sustained figure-eight flight path, and cruise for approximately one hour. This mission requires flight at Reynolds numbers between 150,000 and 200,000 and demands special considerations in the aerodynamic design in order to achieve flight in this regime. Optimal performance requires a light weight configuration with both structural integrity and maximum power availability. The structure design and choice of solar cells for the propulsion was governed by the weight, efficiency, and cost considerations. The final design is a MPRPV weighting 35 N which cruises 7 m/s at the design altitude of 50 m. The configuration includes a wing composed of balsa and foam NACA 6409 airfoil sections and carbon fiber spars, a tail of similar construction, and a truss structure fuselage. The propulsion system consists of 98 10 percent efficient solar cells donated by Mobil Solar, a NiCad battery for energy storage, and a folding propeller regulated by a lightweight and efficient control system. The airfoils and propeller chosen for the design were research and tested during the design process

    Assessing hand osteoarthritis using digital photographs in a community-dwelling population: reliability and associations with radiographic and clinical features

    Get PDF
    Purpose: An atlas for grading hand osteoarthritis (OA) on photographs has been shown to be reliable and associated with clinical examination and radiographic features in a population of older adults (aged ≥69 years) from the AGES-Reykjavik study. The objective of this research was to determine if this atlas was reliable and to assess its association with radiographic and clinical features in a different younger community-dwelling population.Methods: Participants were community-dwelling older adults (≥50 years) in North Staffordshire, UK with self-reported hand pain or hand problems in the last year who attended a research clinic. High quality photographs taken at a set distance in a standardised position were graded for the presence of hand OA using an established atlas. Hand radiographs were graded for OA using the Kellgren Lawrence grading system and the presence of clinical features (nodes, bony enlargement, deformity) was determined on physical examination by trained assessors.Results: Following exclusions 558 participants (mean age 64 years, 62% female) were included in the analyses. Overall reliability for scoring each joint and joint group was good (mean intra-rater ICC =0.79, mean inter-rater ICC =0.71). For each joint and joint group photographic hand OA was positively associated with grade of radiographic OA (rho 0.19-0.57, p<0.001) and the number of clinical features present on an examination (rho 0.36-0.59, p<0.001). At the person level, individuals with higher global photographic hand OA scores had higher summed K&L scores and had higher percentages meeting the ACR clinical hand OA criteria.Conclusions: This photographic scoring system for hand OA has been shown to be reliable and associated with both radiographic and clinical features in a different and younger community-dwelling population to that in which it was developed. This method of data collection offers researchers an feasible alternative to the physical examination and maybe of particular use to large studies and those spread over a wide geographic areas

    Evaluation and optimization of multilayer desigs for astronomical x-ray telescopes using a field-of-view- and energy-dependent figure of merit

    Get PDF
    The three most important quantities used to assess the performance of astronomical x-ray telescope optics are the on-axis collecting area, the field of view, and the half-power diameter. The first two quantities depend on the mirror packing arrangement and the multilayer coating design. In order to optimize the coating design, we have developed a figure-of-merit (FOM) that accounts for the coating response over a specified range of energies and off-axis angles. We present an example where we have used this FOM to optimize a specific coating design for the High Energy Focusing Telescope (HEFT) and to understand tradeoffs between performance and coating thickness

    Multi-Resolution Analysis and Fractional Quantum Hall Effect: an Equivalence Result

    Get PDF
    In this paper we prove that any multi-resolution analysis of \Lc^2(\R) produces, for some values of the filling factor, a single-electron wave function of the lowest Landau level (LLL) which, together with its (magnetic) translated, gives rise to an orthonormal set in the LLL. We also give the inverse construction. Moreover, we extend this procedure to the higher Landau levels and we discuss the analogies and the differences between this procedure and the one previously proposed by J.-P. Antoine and the author.Comment: Submitted to Journal Mathematical Physisc

    Design of a soft gamma-ray focusing telescope for the study of nuclear lines

    Get PDF
    We have studied the design of astronomical multilayer telescopes optimized for performance from 5 to 200 keV. This region of the spectrum contains important nuclear lines that are observable in supernovae and their remnants. The study of these lines can help to differentiate currently competing theories of supernova explosion. Our telescope design will enable us to measure the spectral lines of isotopes such as Ni-56 in Type Ia supernovae and Ti-44 in core-collapse remnants, as well as to observe active galactic nuclei at gamma-ray energies. We considered the performances of multilayers of various material pairs, including W/Si, Pt/C and Ni93V7/Si, as employed in conical-approximation Wolter I optics. We experimented with dividing the energy band of interest into several sections, and optimizing different groups of mirror shells within a single telescope for each smaller energy band. Different material pairs are also used for different energy bands, in order to obtain a higher overall performance. We also consider the significance of the energy bandwidth on the effectiveness of Joensen's parametrization of the multilayer thickness profile, and on the mirror performance within the band

    Knowledge transfer in university-industry research partnerships: a review

    Get PDF
    This paper identifies practices that can facilitate knowledge transfer in university-industry (U-I) research partnerships by systematically reviewing extant literature. We aim to contribute to the theoretical development in the field of academic engagement and propose that knowledge transfer provides a valuable perspective. We started our review with identifying barriers and facilitators of knowledge transfer. Extant literature identified knowledge differences and differences in goals resulting from different institutional cultures as important barriers to knowledge transfer. They result in ambiguity, problems with knowledge absorption and difficulties with the application of knowledge. Trust, communication, the use of intermediaries and experience are found as facilitators for knowledge transfer that help to resolve the identified barriers. Our analysis offers practical advice for the management of academic engagement. Finally, we identified questions for future research based on inconsistencies in extant research and open questions we identified in our analysis
    corecore