3,341 research outputs found
Ecological and Behavioural Correlates of Intracellular Buffering Capacity in the Muscles of Antarctic Fishes
Five species of antarctic fishes can be arranged in order of increasing anaerobic capacity of the white muscles for burst swimming: Rhigophila dearborni (Zoarcidae), icefish (Channichthyidae), Dissostichus mawsoni, Trematomus centronotus, and Pagothenia borchgrevinki (Nototheniidae). This order reflects in-creasing dependence on anaerobic work done during short bursts of speed during prey capture or predator avoidance. Buffer capacity (beta) for white muscle was lower than that of behaviourally equivalent fish from lower latitudes and beta is itself temperature-dependent
Electromagnetic response functions of few-nucleon systems
Inclusive electromagnetic reactions in few-nucleon systems are studied basing
on accurate three- and four-body calculations. The longitudinal 4He(e,e')
response function obtained at q\le 600 MeV/c completely agrees with experiment.
The exact 4He spectral function obtained in a semirealistic potential model is
presented, and the accuracy of the quasielastic response calculated with its
help is assessed, as well as the accuracy of some simpler approximations for
the response. The photodisintegration cross section of 3He obtained with the
realistic AV14 NN force plus UrbanaVIII NNN force agrees with experiment. It is
shown that this cross section is very sensitive to underlying nuclear dynamics
in the E_\gamma\simeq 70-100 MeV region. In particular, the NNN nuclear force
clearly manifests itself in this region.Comment: 10 pages, Latex, style file is included, 7 ps figures, to appear in
Proc. of the 2nd Int. Conf. on Perspectives in Hadronic Physics, ITCP,
Triest, May 1999, World Sci., Singapor
Inhibition of activin/nodal signalling is necessary for pancreatic differentiation of human pluripotent stem cells
Peer reviewedPublisher PD
Critical Josephson Current in a Model Pb/YBa_2Cu_3O_7 Junction
In this article we consider a simple model for a c--axis
Pb/YBa_2Cu_3O_{7-\delta} Josephson junction. The observation of a nonzero
current in such a junction by Sun et al. [A. G. Sun, D. A. Gajewski, M. B.
Maple, R. C. Dynes, Phys. Rev. Lett. 72, 2267 (1994)] has been taken as
evidence against d--wave superconductivity in YBa_2Cu_3O_{7-\delta}. We
suggest, however, that the pairing interaction in the CuO_2 planes may well be
d--wave but that the CuO chains destroy the tetragonal symmetry of the system.
We examine two ways in which this happens. In a simple model of an incoherent
junction, the chains distort the superconducting condensate away from
d_{x^2-y^2} symmetry. In a specular junction the chains destroy the tetragonal
symmetry of the tunneling matrix element. In either case, the loss of
tetragonal symmetry results in a finite Josephson current. Our calculated
values of the critical current for specular junctions are in good agreement
with the results of Sun and co-workers.Comment: Latex File, 21 pages, 6 figures in uuencoded postscript, In Press
(Phys. Rev. B
Neurology
Contains reports on eight research projects.United States Air Force (AF33(616)-7588, AF49(638)-1130)National Science Foundation (Grant G-16526)United States Army Chemical Corps (DA-18-108-405-Cml-942)United States Public Health Service (B-3055, B-3090)United States Navy, Office of Naval Research (Contract Nonr-1841(70)
The high-pressure phase of boron, {\gamma}-B28: disputes and conclusions of 5 years after discovery
{\gamma}-B28 is a recently established high-pressure phase of boron. Its
structure consists of icosahedral B12 clusters and B2 dumbbells in a NaCl-type
arrangement (B2){\delta}+(B12){\delta}- and displays a significant charge
transfer {\delta}~0.5- 0.6. The discovery of this phase proved essential for
the understanding and construction of the phase diagram of boron. {\gamma}-B28
was first experimentally obtained as a pure boron allotrope in early 2004 and
its structure was discovered in 2006. This paper reviews recent results and in
particular deals with the contentious issues related to the equation of state,
hardness, putative isostructural phase transformation at ~40 GPa, and debates
on the nature of chemical bonding in this phase. Our analysis confirms that (a)
calculations based on density functional theory give an accurate description of
its equation of state, (b) the reported isostructural phase transformation in
{\gamma}-B28 is an artifact rather than a fact, (c) the best estimate of
hardness of this phase is 50 GPa, (d) chemical bonding in this phase has a
significant degree of ionicity. Apart from presenting an overview of previous
results within a consistent view grounded in experiment, thermodynamics and
quantum mechanics, we present new results on Bader charges in {\gamma}-B28
using different levels of quantum-mechanical theory (GGA, exact exchange, and
HSE06 hybrid functional), and show that the earlier conclusion about
significant degree of partial ionicity in this phase is very robust
The Extrachromosomal EAST Protein of Drosophila Can Associate with Polytene Chromosomes and Regulate Gene Expression
The EAST protein of Drosophila is a component of an expandable extrachromosomal domain of the nucleus. To better understand its function, we studied the dynamics and localization of GFP-tagged EAST. In live larval salivary glands, EAST-GFP is highly mobile and localizes to the extrachromosomal nucleoplasm. When these cells are permeabilized, EAST-GFP rapidly associated with polytene chromosomes. The affinity to chromatin increases and mobility decreases with decreasing salt concentration. Deleting the C-terminal residues 1535 to 2301 of EAST strongly reduces the affinity to polytene chromosomes. The bulk of EAST-GFP co-localizes with heterochromatin and is absent from transcriptionally active chromosomal regions. The predominantly chromosomal localization of EAST-GFP can be detected in non-detergent treated salivary glands of pupae as they undergo apoptosis, however not in earlier stages of development. Consistent with this chromosomal pattern of localization, genetic evidence indicates a role for EAST in the repression of gene expression, since a lethal east mutation is allelic to the viable mutation suppressor of white-spotted. We propose that EAST acts as an ion sensor that modulates gene expression in response to changing intracellular ion concentrations
Pion interferometry in Au+Au collisions at = 200 GeV
We present a systematic analysis of two-pion interferometry in Au+Au
collisions at = 200 GeV using the STAR detector at RHIC. We
extract the HBT radii and study their multiplicity, transverse momentum, and
azimuthal angle dependence. The Gaussianess of the correlation function is
studied. Estimates of the geometrical and dynamical structure of the freeze-out
source are extracted by fits with blast wave parameterizations. The expansion
of the source and its relation with the initial energy density distribution is
studied.Comment: 21 pages, 30 figures. As published in Physics Review
To respond or not to respond - a personal perspective of intestinal tolerance
For many years, the intestine was one of the poor relations of the immunology world, being a realm inhabited mostly by specialists and those interested in unusual phenomena. However, this has changed dramatically in recent years with the realization of how important the microbiota is in shaping immune function throughout the body, and almost every major immunology institution now includes the intestine as an area of interest. One of the most important aspects of the intestinal immune system is how it discriminates carefully between harmless and harmful antigens, in particular, its ability to generate active tolerance to materials such as commensal bacteria and food proteins. This phenomenon has been recognized for more than 100 years, and it is essential for preventing inflammatory disease in the intestine, but its basis remains enigmatic. Here, I discuss the progress that has been made in understanding oral tolerance during my 40 years in the field and highlight the topics that will be the focus of future research
Photon and neutral pion production in Au+Au collisions at sqrt(s_{NN}) = 130 GeV
We report the first inclusive photon measurements about mid-rapidity
(|y|<0.5) from Au+Au collisions at sqrt(s_{NN}) = 130 GeV at RHIC. Photon pair
conversions were reconstructed from electron and positron tracks measured with
the Time Projection Chamber (TPC) of the STAR experiment. With this method, an
energy resolution of Delta(E)/E = 2% at 0.5 GeV has been achieved.
Reconstructed photons have also been used to measure the transverse momentum
(pt) spectra of pi0 mesons about mid-rapidity (|y| photon
photon decay channel. The fractional contribution of the pi0 -> photon photon
decay to the inclusive photon spectrum decreases by 20% +/- 5% between pt =
1.65 GeV/c and pt = 2.4 GeV/c in the most central events, indicating that
relative to pi0 -> photon photon decay the contribution of other photon sources
is substantially increasing.Comment: 13 pages, 14 figures, submitted to Phys. Rev.
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