96 research outputs found
Performances techniques et économiques de 2 troupeaux ovins expérimentaux conduits en Agriculture Biologique (AB).
Deux troupeaux ovins allaitants en AB ont été comparés en ferme expérimentale, menés selon 2 conduites de la reproduction : 3 agnelages en 2 ans (système accéléré) ou une mise bas par an (système herbager). Leurs performances techniques et économiques ont été analysées et comparées à celles d’élevages privés. En système accéléré, la productivité numérique est légèrement supérieure (6 % : 161 vs 152 en moyenne sur 3 ans) mais, même lorsque l’écart est élevé (en 2002 : 193 vs 152), la marge par brebis est peu supérieure (90€ vs 86) du fait de coûts de production élevés. En effet, les concentrés utilisés atteignent 178 kg/brebis (+58 %) avec un prix 60 % plus élevé qu’en conventionnel. Par ailleurs, les résultats de ce système sont irréguliers. Le système herbager, moins intensif pour l’animal, est l’illustration d’un compromis entre niveau des performances zootechniques élevé et maîtrise des charges d’alimentation avec maximisation de l’utilisation des ressources fourragères
Controlling reproduction in organic sheep breeding: the influence of breeding factors on the effectiveness of the ram effect
The ram effect, which is a natural method for the control of reproduction in sheep, is an alternative to hormone treatments that are banned on organic farms. The ram effect induces a combination of ovulation and oestrus in ewes that is acyclic and conducive to artificial insemination. The proportion of acyclic females with induced ovulation and their subsequent fertility at the first oestrus is variable. The control of some breeding factors that have been studied here may help to reduce this variability. The proportion of ewes induced to ovulate by rams increased as the season advanced (54% in April vs. 84% at the end of May, p<0.05) and with a longer time period between drying-off and mating: from 29% to 84% (p<0.001) for 22 and 86 days elapsed, respectively. The fertility of these ewes at the first oestrus was also higher at the end of May than in April (86% vs. 39%, p<0.01) and increased with the amount of time elapsed since drying-off (55% and 81% for 22 and 86 days, respectively; p=0.09). The time that the first oestrus occurs is later for lean ewes because they have a higher proportion of short cycles (67%) than fat ewes (41%, p<0.05)
Assessing a treatment on the basis of an individual or a group. An example: the homeopathic treatment of digestive-tract strongyles in sheep
Homeopathic treatments, widely used in organic farming, remain unevaluated. Assessment is difficult since the individuals that respond to treatment are not identified, although it is central to the concept of homeopathic treatment. Classifying lambs into those to be treated (since they have high parasitic infection rate or poor production performances) or that should remain untreated (in other words, even when treated, they will not benefit from treatment) is not simple. The identification of lambs to be treated can be based on parasitological examinations (eggs per gram of faeces), clinical (anaemia or diarrhoea)or production-related (weight gain) results. The classification of lambs was a posteriori and based on dendrograms using UPGMA (unweighted pairwise grouping on arithmetic average) and Gower’s similarity index. Parasitological, clinical and production identifiers were used for assessing the efficacy of Teucrium marum (9 CH) on digestive-tract strongyles. There was no reduction in gastro-intestinal infection in lambs with high infection rates or poor live weight gain
Realizing Envisat's potential for rain cloud studies
Owing to the highly variable nature of rain both in space and time and the difficulties in obtaining accurate in situ measurements, increasing reliance is being placed on the various types of satellite data now available. The multi-sensor payload of Envisat is of particular interest because the data are co-located and simultaneous, thus reducing some of the uncertainty found in multi-platform analyses. This paper shows variations in cloud and precipitation data derived from AATSR, RA-2 and MWR-2 measurements in an overpass of Hurricane Juan, revealing significant asymmetry in the spatial distribution. The results are discussed in the context of similar data from other tropical and sub-tropical features in the western Atlantic. The combination of data from these sensors allows us to see the effects of different drop-size distribution at varying distances from the eye and to
conclude that active microwave systems are needed for studying small-scale variations in rainfall
Role of Interleukin 17 in arthritis chronicity through survival of synoviocytes via regulation of synoviolin expression
Background:
The use of TNF inhibitors has been a major progress in the treatment of chronic inflammation. However, not all patients respond. In addition, response will be often lost when treatment is stopped. These clinical aspects indicate that other cytokines might be involved and we focus here on the role of IL-17. In addition, the chronic nature of joint inflammation may contribute to reduced response and enhanced chronicity. Therefore we studied the capacity of IL-17 to regulate synoviolin, an E3 ubiquitin ligase implicated in synovial hyperplasia in human rheumatoid arthritis (RA) FLS and in chronic reactivated streptococcal cell wall (SCW)-induced arthritis.<p></p>
Methodology/Principal Findings:
Chronic reactivated SCW-induced arthritis was examined in IL-17R deficient and wild-type mice. Synoviolin expression was analysed by real-time RT-PCR, Western Blot or immunostaining in RA FLS and tissue, and p53 assessed by Western Blot. Apoptosis was detected by annexin V/propidium iodide staining, SS DNA apoptosis ELISA kit or TUNEL staining and proliferation by PCNA staining. IL-17 receptor A (IL-17RA), IL-17 receptor C (IL-17-RC) or synoviolin inhibition were achieved by small interfering RNA (siRNA) or neutralizing antibodies. IL-17 induced sustained synoviolin expression in RA FLS. Sodium nitroprusside (SNP)-induced RA FLS apoptosis was associated with reduced synoviolin expression and was rescued by IL-17 treatment with a corresponding increase in synoviolin expression. IL-17RC or IL-17RA RNA interference increased SNP-induced apoptosis, and decreased IL-17-induced synoviolin. IL-17 rescued RA FLS from apoptosis induced by synoviolin knockdown. IL-17 and TNF had additive effects on synoviolin expression and protection against apoptosis induced by synoviolin knowndown. In IL-17R deficient mice, a decrease in arthritis severity was characterized by increased synovial apoptosis, reduced proliferation and a marked reduction in synoviolin expression. A distinct absence of synoviolin expressing germinal centres in IL-17R deficient mice contrasted with synoviolin positive B cells and Th17 cells in synovial germinal centre-like structures.<p></p>
Conclusion/Significance:
IL-17 induction of synoviolin may contribute at least in part to RA chronicity by prolonging the survival of RA FLS and immune cells in germinal centre reactions. These results extend the role of IL-17 to synovial hyperplasia.<p></p>
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Antarctic icebergs: A significant natural ocean sound source in the Southern Hemisphere
In late 2007, two massive icebergs, C19a and B15a, drifted into open water and slowly disintegrated in the southernmost Pacific Ocean. Archived acoustic records show that the high-intensity underwater sounds accompanying this breakup increased ocean noise levels at mid-to-equatorial latitudes over a period of ~1.5 years. More typically, seasonal variations in ocean noise, which are characterized by austral summer-highs and winter-lows, appear to be modulated by the annual cycle of Antarctic iceberg drift and subsequent disintegration. This seasonal pattern is observed in all three Oceans of the Southern Hemisphere. The life cycle of Antarctic icebergs affects not only marine ecosystem but also the sound environment in far-reaching areas and must be accounted for in any effort to isolate anthropogenic or climate-induced noise contributions to the ocean soundscape.Keywords: Trend, Seasonality, Antarctica, Ocean noise, Iceber
The relationship between demographic- and disease-related variables and health-related quality of life in patients with axial spondyloarthritis
Globcurrent: Sentinel-3 synergy in action
The ESA Data User Element (DUE) funded GlobCurrent project (http://www.globcurrent.org) aims to: (i) advance the quantitative estimation of ocean surface currents from satellite sensor synergy; and (ii) demonstrate impact in user-led scientific, operational and commercial applications that, in turn, will improve and strengthen the uptake of satellite measurements. Today, a synergetic approach for quantitative analysis can build on high-resolution imaging radar and spectrometer data, infrared radiometer data and radar altimeter measurements. It will further integrate Sentinel-3 in combination with Sentinel-1 SAR data. From existing and past missions, it is often demonstrated that sharp gradients in the sea surface temperature (SST) field and the ocean surface chlorophyll-a distribution are spatially correlated with the sea surface roughness anomaly fields at small spatial scales, in the sub-mesocale (1-10 km) to the mesoscale (30-80 km). At the larger mesoscale range (>50 km), information derived from radar altimeters often depict the presence of coherent structures and eddies. The variability often appears largest in regions where the intense surface current regimes (>100 - 200 km) are found. These 2-dimensional structures manifested in the satellite observations represent evidence of the upper ocean (~100-200 m) dynamics. Whereas the quasi geostrophic assumption is valid for the upper ocean dynamics at the larger scale (>100 km), possible triggering mechanisms for the expressions at the mesoscale-to-submesoscale may include spiraling tracers of inertial motion and the interaction of the wind-driven Ekman layer with the quasi-geostrophic current field. This latter, in turn, produces bands of downwelling (convergence) and upwelling (divergence) near fronts. A regular utilization of the sensor synergy approach with the combination of Sentinel-3 and Sentinel-1 will provide a highly valuable data set for further research and development to better relate the 2-dimensional surface expressions and the upper ocean dynamics
Comparison of non-radiographic axial spondyloarthritis and ankylosing spondylitis patients – baseline characteristics, treatment adherence, and development of clinical variables during three years of anti-TNF therapy in clinical practice
LLANO DE LOS JUNCOS. TEJEDA [Material gráfico]
Copia digital. Madrid : Ministerio de Educación, Cultura y Deporte, 201
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